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2023 ESC Guidelines for the management of cardiomyopathies
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Both the 2024 ACC/AHA and 2023 ESC guidelines give non-dihydropyridine calcium channel blockers a class I recommendation for patients in whom beta blockers are ineffective or not well tolerated.
“Both the 2024 ACC/AHA and 2023 ESC guidelines give non-dihydropyridine CCBs a class I recommendation for patients in whom β blockers are ineffective or not well tolerated (table 2). 1 22”
From Current management of hypertrophic cardiomyopathy (2025) · cites this paper as [1]
Section 7.1.4.1 says verapamil can be used when beta-blockers are contraindicated or ineffective, and diltiazem should be considered when beta-blockers and verapamil are not tolerated or are contraindicated. The retrieved passages do not establish a Class I recommendation for both drugs, and the diltiazem condition is narrower than the claim states. This verdict addresses only the cited ESC guideline, not the ACC/AHA guideline. (LLM, conf=0.76)
Experimental — accuracy not yet measuredCurrent ESC and ACC guidelines recommend anti-obstructive therapy (beta-blockers or verapamil) to reduce gradient and symptoms in HOCM.
“Current guidelines from the European Society of Cardiology (ESC) and the American College of Cardiology (ACC) recommend anti-obstructive therapy, i.e., beta-blockers or verapamil to reduce gradient and symptoms (6–8).”
From Discontinuation of afterload-reducing drugs decreases left ventricular outflow tract obstruction in hypertrophic obstructive cardiomyopathy (2024) · cites this paper as [8]
The 2023 ESC guidelines assigned a class 2a recommendation to use cardiac myosin inhibitors in patients with symptomatic hypertrophic cardiomyopathy with left ventricular outflow tract obstruction, in addition to beta blockers or calcium channel blockers or as monotherapy when beta blockers, calcium channel blockers, or disopyramide are not tolerated or contraindicated, before considering septal减少
“The 2023 ESC guidelines assigned a class 2a recommendation to use of CMIs in patients with symptomatic hypertrophic cardiomyopathy with LVOT obstruction, in addition to β blockers or CCBs or as monotherapy when β blockers, CCBs, or disopyramide are not tolerated or contraindicated, before considering SRT. 1”
From Current management of hypertrophic cardiomyopathy (2025) · cites this paper as [1]
US guidelines primarily take a dichotomized, algorithmic approach, whereas the European guidelines advise use of the HCM Risk-SCD calculator.
“US guidelines primarily take a dichotomized, algorithmic approach, 22 whereas the European guidelines advise use of the HCM Risk-SCD calculator”
From Current management of hypertrophic cardiomyopathy (2025) · cites this paper as [1]
The diagnosis of HCM was based on the latest ESC guidelines for the diagnosis and management of hypertrophic cardiomyopathies.
“The diagnosis of HCM was based on the latest ESC guidelines for the diagnosis and management of hypertrophic cardiomyopathies: patients with familial or genetically diagnosed HCM with wall thickness ≥13 mm in one or more left ventricular myocardial segments or patients with wall thickness ≥15 mm in the absence of any other cause of hypertrophy (7, 8).”
From Discontinuation of afterload-reducing drugs decreases left ventricular outflow tract obstruction in hypertrophic obstructive cardiomyopathy (2024) · cites this paper as [8]
Current European guidelines recommend a combined approach, using the risk score for an initial stratification, with further delineation of the need for an ICD based on presence of other clinical factors for patients with calculator estimated low (five year <4%) risk.
“current European guidelines recommend a combined approach, using the risk score for an initial stratification, with further delineation of the need for an ICD, based on presence of other clinical factors for patients with calculator estimated low (five year <4%) risk.”
From Current management of hypertrophic cardiomyopathy (2025) · cites this paper as [1]
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Metadata
- Authors
- Arbelo, E., Protonotarios, A., Gimeno, J. R., Arbustini, E., Barriales-Villa, R., Basso, C., Bezzina, C. R., Biagini, E., Blom, N. A., de Boer, R. A., De Winter, T., Elliott, P. M., Flather, M., Garcia-Pavia, P., Haugaa, K. H., Ingles, J., Jurcut, R. O., Klaassen, S., Limongelli, G., Loeys, B., Mogensen, J., Olivotto, I., Pantazis, A., Sharma, S., Van Tintelen, J. P., Ware, J. S., Kaski, J. P., ESC Scientific Document Group, Charron, P., Imazio, M., Abdelhamid, M., Aboyans, V., Arad, M., Asselbergs, F. W., Asteggiano, R., Bilinska, Z., Bonnet, D., Bundgaard, H., Cardim, N. M., Čelutkienė, J., Cikes, M., De Ferrari, G. M., Dusi, V., Falk, V., Fauchier, L., Gandjbakhch, E., Heliö, T., Koskinas, K., Kotecha, D., Landmesser, U., Lazaros, G., Lewis, B. S., Linhart, A., Løchen, M.-L., Meder, B., Mindham, R., Moon, J., Nielsen, J. C., Petersen, S., Prescott, E., Sheppard, M. N., Sinagra, G., Sitges, M., Tfelt-Hansen, J., Touyz, R., Veltrop, R., Veselka, J., Wahbi, K., Wilde, A., Zeppenfeld, K., Kichou, B., Sisakian, H., Scherr, D., Gerber, B., Džubur, A., Gospodinova, M., Planinc, I., Moustra, H. H., Zemánek, D., Jensen, M. S. K., Samir, A., Palm, K., Heliö, T., Wahbi, K., Schulze-Bahr, E., Haralambos, V., Sepp, R., Aðalsteinsdóttir, B., Ward, D., Blich, M., Sinagra, G., Poniku, A., Lunegova, O., Rudzitis, A., Kassab, R., Barysienė, J., Huijnen, S., Felice, T., Vataman, E., Pavlovic, N., Doghmi, N., Asselbergs, F. W., Kostovska, E. S., Almaas, V. M., Biernacka, E. K., Brito, D., Rosca, M., Zavatta, M., Ristic, A., Goncalvesová, E., Šinkovec, M., Cañadas-Godoy, V., Platonov, P. G., Saguner, A. M., Saadi, A. R. A., Kammoun, I., Celik, A., Nesukay, E., Abdullaev, T., Prescott, E., James, S., Arbelo, E., Baigent, C., Borger, M. A., Buccheri, S., Ibanez, B., Køber, L., Koskinas, K. C., McEvoy, J. W., Mihaylova, B., Mindham, R., Neubeck, L., Nielsen, J. C., Pasquet, A., Rakisheva, A., Rocca, B., Rossello, X., Vaartjes, I., Vrints, C., Witkowski, A., & Zeppenfeld, K.
- Affiliations
- (Task Force Co-ordinator) ( )
- (Italy)
- (Spain)
- (Netherlands)
- (Belgium)
- (United Kingdom)
- (Sweden)
- (Australia)
- (Romania)
- (Germany)
- (Denmark)
- (Chairperson) ( )
- ORCID
- Protonotarios, Alexandros
- Gimeno, Juan R
- Arbustini, Eloisa
- Barriales-Villa, Roberto
- Basso, Cristina
- Bezzina, Connie R
- Biagini, Elena
- de Boer, Rudolf A
- Elliott, Perry M
- Flather, Marcus
- Garcia-Pavia, Pablo
- Haugaa, Kristina H
- Ingles, Jodie
- Jurcut, Ruxandra Oana
- Klaassen, Sabine
- Limongelli, Giuseppe
- Loeys, Bart
- Mogensen, Jens
- Olivotto, Iacopo
- Pantazis, Antonis
- Sharma, Sanjay
- Van Tintelen, J Peter
- Ware, James S
- Kaski, Juan Pablo
- Venue
- European Heart Journal
- Publisher
- Oxford University Press (OUP)
- Published
- 2023-08-25
- Volume
- 44
- Issue
- 37
- Pages
- 3503-3626
- ISSN
- 0195-668X
- 1522-9645
- Cited by
- 2,844
- References
- 50
- Language
- en
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
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