Cited by 1,939Atrial Fibrillation Management and OutcomesAcute Ischemic Stroke ManagementCardiac electrophysiology and arrhythmias

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Prevalence, incidence and lifetime risk of atrial fibrillation: the Rotterdam study

Heeringa, Jan, van der Kuip, Deirdre A.M., Hofman, Albert, Kors, Jan A., van Herpen, Gerard, Stricker, Bruno H.Ch., Stijnen, Theo, Lip, Gregory Y.H., Witteman, Jacqueline C.M.·2006·European Heart Journal

DOI 10.1093/eurheartj/ehi825

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Abstract

AIMS: We aimed to investigate the prevalence and incidence of atrial fibrillation (AF) in a large European population-based study. METHODS AND RESULTS: The study is part of the Rotterdam study, a population-based prospective cohort study among subjects aged 55 years and above. The prevalence at baseline was assessed in 6808 participants. Incidence of AF was investigated during a mean follow-up period of 6.9 years in 6432 persons. We identified 376 prevalent and 437 incident cases. Overall prevalence was 5.5%, rising from 0.7% in the age group 55-59 years to 17.8% in those aged 85 years and above. The overall incidence rate was 9.9/1000 person-years. The incidence rate in the age group 55-59 years was 1.1/1000 person-years, rose to 20.7/1000 person-years in the age group 80-84 years and stabilized in those aged 85 years and above. Prevalence and incidence were higher in men than in women. The lifetime risk to develop AF at the age of 55 years was 23.8% in men and 22.2% in women. CONCLUSION: In this prospective study in a European population, the prevalence and incidence of AF increased with age and were higher in men than in women. The high lifetime risk to develop AF was similar to North American epidemiological data.

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Authors: Heeringa, J., van der Kuip, D. A. M., Hofman, A., Kors, J. A., van Herpen, G., Stricker, B. H. C., Stijnen, T., Lip, G. Y. H., & Witteman, J. C. M.
Affiliations: Erasmus MC (NL)
Birmingham City Hospital (GB)
Corresponding author: Heeringa, Jan
ORCID: Kors, Jan A.
Stricker, Bruno H.Ch.
Stijnen, Theo
Lip, Gregory Y.H.
Venue: European Heart Journal
Publisher: Oxford University Press (OUP)
Published: 2006-03-09
Volume: 27
Issue: 8
Pages: 949-953
ISSN: 0195-668X (ISSN-L)
1522-9645
DOI: 10.1093/eurheartj/ehi825
OpenAlex: W2148056560
Cited by: 1,939
References: 37
Citations by year: 2026: 38 · 2025: 58 · 2024: 87 · 2023: 89 · 2022: 105 · 2021: 109 · 2020: 142 · 2019: 122 · 2018: 123 · 2017: 146 · 2016: 112 · 2015: 153 · 2014: 118 · 2013: 141 · 2012: 113
FWCI: 31.18
Type: journal article
Language: en
Open access: closed
Locations: European Heart Journal (publishedVersion)
PubMed (publishedVersion)
EUR Research Repository (Erasmus University Rotterdam) (publishedVersion)
EUR Research Repository (Erasmus University Rotterdam) (submittedVersion)
HighWire Press Open Archive (submittedVersion)
Digest of the World Core Medical Journals(Cardiology)
Topics: Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Atrial Fibrillation Management and Outcomes
Health Sciences › Medicine › Clinical Neurology › Acute Ischemic Stroke Management
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac electrophysiology and arrhythmias
Keywords: atrial fibrillation, prevalence, incidence, lifetime risk, age differences, sex differences, older adults, Rotterdam Study
MeSH terms: Aged, Aged, 80 and over, Atrial Fibrillation, Epidemiologic Methods, Female, Humans, Male, Middle Aged, Netherlands, Age Distribution, Sex Distribution

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Prevalence, incidence and lifetime risk of atrial fibrillation: the Rotterdam study

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