The DOI matches its Crossref record; 141 of the 141 references it cites were found in a registry or an index.
Early and comprehensive management of atrial fibrillation: executive summary of the proceedings from the 2nd AFNET-EHRA consensus conference ‘research perspectives in AF’
Open accessAbstract
Atrial fibrillation (AF) causes important mortality and morbidity on a population-level. So far, we do not have the means to prevent AF or AF-related complications adequately. Therefore, over 70 experts on atrial fibrillation convened for the 2nd AFNET/EHRA consensus conference to suggest directions for research to improve management of AF patients (Supplementary Data). The group defined three main areas in need for research in AF: 1. better understanding of the mechanisms of AF; 2. Improving rhythm control monitoring and management; and 3. comprehensive cardiovascular risk management in AF patients. The group put forward the hypothesis that successful therapy of AF and its associated complications will require comprehensive therapy. This applies e.g. to the “old” debate of “rate versus rhythm control”, since rhythm control is generally added to underlying (continued) rate control therapy, but also to the emerging debate of “antiarrhythmic drugs versus catheter ablation”, of which both may be needed in most patients to maintain sinus rhythm, but also to therapy of conditions that predispose to AF and contribute to cardiovascular complications such as stroke, cognitive decline, heart failure, and acute coronary syndromes. We call for research initiatives aiming at a better understanding of the different causes of AF and its complications, and at development and validation of mechanism-based therapies. The future of AF therapy may require a combination of management of underlying and concomitant conditions, early and comprehensive rhythm control therapy, adequate control of ventricular rate and cardiac function, and continuous therapy to prevent AF-associated complications (e.g. antithrombotic therapy). The reasons for these suggestions are detailed in this paper.
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In the citing paper
“Paroxysmal AF is often missed.120”
From 2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS (2016) · cites this paper as [120]
In the citing paper
“Silent, undetected AF is common, 120,122 with severe consequences such as stroke and death.[123][124][125]”
From 2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS (2016) · cites this paper as [120]
In the citing paper
“Repeated daily ECG recordings increased the detection of silent, asymptomatic paroxysmal AF in an unselected Swedish population aged > 75 years.120,135”
From 2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS (2016) · cites this paper as [120]
In the citing paper
“Furthermore, asymptomatic recurrences of AF are common in patients with symptomatic AF. 120”
From 2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS (2016) · cites this paper as [120]
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Engdahl, J., Andersson, L., Mirskaya, M., & Rosenqvist, M. (2013) · Circulation · doi:10.1161/circulationaha.112.126656 · Cited by 233
Metadata
- Authors
- Kirchhof, P., Bax, J., Blomstrom-Lundquist, C., Calkins, H., Camm, A. J., Cappato, R., Cosio, F., Crijns, H., Diener, H.-C., Goette, A., Israel, C. W., Kuck, K.-H., Lip, G. Y. H., Nattel, S., Page, R. L., Ravens, U., Schotten, U., Steinbeck, G., Vardas, P., Waldo, A., Wegscheider, K., Willems, S., & Breithardt, G.
- Affiliations
- University of Münster (DE)
- Leiden University (NL)
- Uppsala University (SE)
- Johns Hopkins University (US)
- St George's, University of London (GB)
- Policlinico S. Matteo 6 Department of Cardiology , , Pavia ,
- Hospital Telleras 7 , Madrid ,
- Maastricht University (NL)
- University of Duisburg-Essen (DE)
- Otto-von-Guericke-Universität Magdeburg (DE)
- Goethe University Frankfurt (DE)
- General Hospital St Georg 12 Department of Cardiology , , Hamburg ,
- University of Birmingham (GB)
- Montreal Heart Institute (CA)
- University of Washington (US)
- Technische Universität Dresden (DE)
- Ludwig-Maximilians-Universität München (DE)
- University of Crete (GR)
- Case Western Reserve University (US)
- Universität Hamburg (DE)
- Corresponding author
- Kirchhof, Paulus
- ORCID
- Venue
- European Heart Journal
- Publisher
- Oxford University Press (OUP)
- Published
- 2009-06-17
- Volume
- 30
- Issue
- 24
- Pages
- 2969-2980
- ISSN
- 0195-668X (ISSN-L)
- 1522-9645
- OpenAlex
- W1970627024
- Cited by
- 202
- References
- 140
- Citations by year
- 2026: 4 · 2025: 5 · 2024: 2 · 2023: 7 · 2022: 12 · 2021: 14 · 2020: 8 · 2019: 6 · 2018: 8 · 2017: 10 · 2016: 14 · 2015: 13 · 2014: 16 · 2013: 16 · 2012: 23
- FWCI
- 14.45
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- European Heart Journal (publishedVersion)
- PubMed (publishedVersion)
- HighWire Press Open Archive (submittedVersion)
- University of Birmingham Research Portal (University of Birmingham) (submittedVersion)
- Funders
- Kompetenznetz Vorhofflimmern
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Atrial Fibrillation Management and Outcomes
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Arrhythmias and Treatments
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac pacing and defibrillation studies
- Keywords
- atrial fibrillation, atrial fibrillation management, rhythm control, rate control, antiarrhythmic drugs, catheter ablation, cardiovascular risk management, stroke prevention, antithrombotic therapy, heart failure, cognitive decline, acute coronary syndrome, mechanism-based therapy, atrial fibrillation mechanisms
- MeSH terms
- Anti-Arrhythmia Agents, Atrial Fibrillation, Fibrinolytic Agents, Humans, Patient Compliance, Risk Factors, Risk Management, Catheter Ablation, Stroke
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