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Mode of onset of ventricular fibrillation in patients with early repolarization pattern vs Brugada syndrome
Open accessAbstract
AIMS: The aim of the present study was to identify specific electrocardiogram (ECG) features that predict the development of multiple episodes of ventricular fibrillation (VF) in patients with an early repolarization (ER) pattern and to compare the mode of VF initiation with that observed in typical cases of Brugada syndrome (BrS). METHODS AND RESULTS: The mode of the onset and the coupling intervals of the premature ventricular contractions (PVCs) initiating VF episodes were analysed in patients with BrS (n = 8) or ER who experienced sudden cardiac death/syncope or repeated appropriate implantable cardioverter defibrillator shocks. Among the 11 patients with ER, 5 presented with electrical storm (ES, four or more recurrent VF episodes/day). The five ES patients displayed a dramatic but very transient accentuation of J waves across the precordial and limb leads prior to the development of ES. Ventricular fibrillation episodes were more commonly initiated by PVCs with a short-long-short (SLS) sequence in ER (42/58, 72.4%) vs. BrS patients (13/86, 15.1%, P < 0.01). Coupling intervals were significantly shorter in the ER group compared with those with BrS [328 (320, 340) ms vs. 395 (350, 404) ms, P < 0.01]. CONCLUSION: Our study provides additional evidence in support of the hypothesis that ER pattern in the ECG is not always benign. Transient augmentation of global J waves may be indicative of a highly arrhythmogenic substrate heralding multiple episodes of VF in patients with ER pattern. Ventricular tachycardia/VF initiation is more commonly associated with an SLS sequence, and PVCs display a shorter coupling interval in patients with ER pattern compared with those with BrS.
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Cites
Brugada Syndrome: Report of the Second Consensus Conference
Antzelevitch, C. N., Brugada, P., Borggrefe, M. M., Brugada, J., Brugada, R., Corrado, D., Gussak, I. B., Marec, H. L., Nademanee, K., Pérez‐Riera, A. R., et al. (2005) · Circulation · doi:10.1161/01.cir.0000152479.54298.51 · Cited by 1,807
Self-citationSudden Cardiac Arrest Associated with Early Repolarization
Haïssaguerre, M., Derval, N., Sacher, F., Jesel, L., Deisenhofer, I., de Roy, L., Pasquié, J.-L., Nogami, A., Babuty, D., Yli-Mayry, S., et al. (2008) · New England Journal of Medicine · doi:10.1056/nejmoa071968 · Cited by 1,449
Yan, G., & Antzelevitch, C. (1999) · Circulation · doi:10.1161/01.cir.100.15.1660 · Cited by 1,132
Self-citationCellular Basis for the Electrocardiographic J Wave
Yan, G., & Antzelevitch, C. (1996) · Circulation · doi:10.1161/01.cir.93.2.372 · Cited by 812
Self-citationJ-Point Elevation in Survivors of Primary Ventricular Fibrillation and Matched Control Subjects
Rosso, R., Kogan, E., Belhassen, B., Rozovski, U., Scheinman, M. M., Zeltser, D., Halkin, A., Steinvil, A., Heller, K., Glikson, M., et al. (2008) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2008.07.010 · Cited by 566
Liu, D. W., Gintant, G. A., & Antzelevitch, C. (1993) · Circulation Research · doi:10.1161/01.res.72.3.671 · Cited by 462
Self-citationTransient outward current prominent in canine ventricular epicardium but not endocardium.
Litovsky, S. H., & Antzelevitch, C. N. (1988) · Circulation Research · doi:10.1161/01.res.62.1.116 · Cited by 436
Self-citationKasanuki, H., Ohnishi, S., Ohtuka, M., Matsuda, N., Nirei, T., Isogai, R., Shoda, M., Toyoshima, Y., & Hosoda, S. (1997) · Circulation · doi:10.1161/01.cir.95.9.2277 · Cited by 419
Ionic and Cellular Basis for the Predominance of the Brugada Syndrome Phenotype in Males
Diego, J. M. D., Cordeiro, J. M., Goodrow, R. J., Fish, J. M., Zygmunt, A. C., Pérez, G. J., Scornik, F. S., & Antzelevitch, C. N. (2002) · Circulation · doi:10.1161/01.cir.0000032002.22105.7a · Cited by 393
Self-citationEarly repolarization syndrome: Clinical characteristics and possible cellular and ionic mechanisms
Gussak, I. B., & Antzelevitch, C. N. (2000) · Journal of Electrocardiology · doi:10.1054/jelc.2000.18106 · Cited by 347
Self-citationAntzelevitch, C. (2006) · Pacing and Clinical Electrophysiology · doi:10.1111/j.1540-8159.2006.00507.x · Cited by 303
Self-citationAugmentation of J Waves and Electrical Storms in Patients with Early Repolarization
Nam, G., Kim, Y., & Antzelevitch, C. N. (2008) · New England Journal of Medicine · doi:10.1056/nejmc0708182 · Cited by 291
Self-citationHaı̈ssaguerre, M., Chatel, S., Sacher, F., Weerasooriya, R., Probst, V., Loussouarn, G., Horlitz, M., LIERSCH, R., Schulze‐Bahr, E., Wilde, A. A. M., et al. (2008) · Journal of Cardiovascular Electrophysiology · doi:10.1111/j.1540-8167.2008.01326.x · Cited by 285
The normal RS-T segment elevation variant∗
Wasserburger, R. H., & Alt, W. J. (1961) · The American Journal of Cardiology · doi:10.1016/0002-9149(61)90204-1 · Cited by 256
Ikeda, T., Sakurada, H., Sakabe, K., Sakata, T., Takami, M., Tezuka, N., Nakae, T., Noro, M., Enjoji, Y., Tejima, T., et al. (2001) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(01)01197-4 · Cited by 247
Kalla, H., Yan, G., & Marinchak, R. A. (2000) · Journal of Cardiovascular Electrophysiology · doi:10.1111/j.1540-8167.2000.tb00743.x · Cited by 225
Dynamic Changes of 12‐Lead Electrocardiograms in a Patient with Brugada Syndrome
Matsuo, K., Shimizu, W., Kurita, T., Inagaki, M., Aihara, N., & Kamakura, S. (1998) · Journal of Cardiovascular Electrophysiology · doi:10.1111/j.1540-8167.1998.tb01843.x · Cited by 161
Diego, J. M. D., & Antzelevitch, C. (1993) · Circulation · doi:10.1161/01.cir.88.3.1177 · Cited by 154
Self-citationSudden death in patients without structural heart disease
WEVER, E. F. D., & de Medina, E. O. R. (2004) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2003.10.053 · Cited by 133
TAKAGI, M., Aihara, N., Takaki, H., Taguchi, A., Shimizu, W., Kurita, T., Suyama, K., & KAMAKURA, S. (2000) · Journal of Cardiovascular Electrophysiology · doi:10.1111/j.1540-8167.2000.tb00062.x · Cited by 124
Early Repolarization on Scalar Electrocardiogram
Mehta, M. C., & Jain, A. C. (1995) · The American Journal of the Medical Sciences · doi:10.1097/00000441-199506000-00001 · Cited by 123
Calloe, K., Cordeiro, J., Diego, J. D. D., Hansen, R., Grunnet, M., Olesen, S., & Antzelevitch, C. (2008) · Cardiovascular Research · doi:10.1093/cvr/cvn339 · Cited by 120
Self-citationShu, J., Zhu, T., Yang, L., Cui, C., & Yan, G. (2005) · Journal of Electrocardiology · doi:10.1016/j.jelectrocard.2005.06.006 · Cited by 113
Characterization of J wave in a patient with idiopathic ventricular fibrillation
Shinohara, T., Takahashi, N., Saikawa, T., & Yoshimatsu, H. (2006) · Heart Rhythm · doi:10.1016/j.hrthm.2006.05.016 · Cited by 112
Cellular Basis for the Repolarization Waves of the ECG
Antzelevitch, C. N. (2006) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1380.021 · Cited by 82
Self-citationBrugada syndrome with atypical ECG: downsloping ST-segment elevation in inferior leads
Pérez‐Riera, A. R., Ferreira, C., Schapachnik, E., Sanches, P. C. R., & Moffa, P. J. (2004) · Journal of Electrocardiology · doi:10.1016/j.jelectrocard.2004.01.002 · Cited by 81
Brugada Syndrome Characterized by the Appearance of J Waves
Daimon, M., Inagaki, M., 諸岡, 茂., Fukuzawa, S., Sugioka, J., Kushida, S., Tateno, K., & Ozawa, S. (2000) · Pacing and Clinical Electrophysiology · doi:10.1111/j.1540-8159.2000.tb06770.x · Cited by 26
Komiya, N., Imanishi, R., Kawano, H., Shibata, R., Moriya, M., Fukae, S., Doi, Y., Nakao, K., Seto, S., & Yano, K. (2006) · Pacing and Clinical Electrophysiology · doi:10.1111/j.1540-8159.2006.00481.x · Cited by 17
Brugada Syndrome with ST‐Segment Elevation in the Lateral Leads
van den Berg, M. P., & Wiesfeld, A. C. P. (2006) · Journal of Cardiovascular Electrophysiology · doi:10.1111/j.1540-8167.2006.00525.x · Cited by 13
Geller, J. C., Reek, S., GOETTE, A., & KLEIN, H. U. (2001) · Journal of Cardiovascular Electrophysiology · doi:10.1046/j.1540-8167.2001.01094.x · Cited by 13
Cited by
Sorted by citations
Priori, S. G., Wilde, A. A., Horie, M., Cho, Y., Behr, E. R., Berul, C., Blom, N., Brugada, J., Chiang, C.-E., Huikuri, H., et al. (2013) · Heart Rhythm · doi:10.1016/j.hrthm.2013.05.014 · Cited by 1,942
Role of the Autonomic Nervous System in Modulating Cardiac Arrhythmias
Shen, M. J., & Zipes, D. P. (2014) · Circulation Research · doi:10.1161/circresaha.113.302549 · Cited by 867
J Wave Syndromes Consensus Conference: Emerging Concepts & Gaps in Knowledge
Antzelevitch, C., Yan, G.-X., Ackerman, M., Borggrefe, M., Corrado, D., Guo, J.-H., Gussak, I., Hasdemir, C., Horie, M., Huikuri, H., et al. (2016) · Heart Rhythm · doi:10.1016/j.hrthm.2016.05.024 · Cited by 239
Self-citationPriori, S. G., Wilde, A. A. M., Horie, M., Cho, Y., Behr, E. R., Berul, C. I., Blom, N. A., Brugada, J., Chiang, C., Huikuri, H. V., et al. (2013) · EP Europace · doi:10.1093/europace/eut272 · Cited by 626
Antzelevitch, C., & Yan, G.-X. (2009) · Heart Rhythm · doi:10.1016/j.hrthm.2009.12.006 · Cited by 554
Self-citation
Metadata
- Authors
- Nam, G.-B., Ko, K.-H., Kim, J., Park, K.-M., Rhee, K.-S., Choi, K.-J., Kim, Y.-H., & Antzelevitch, C.
- Affiliations
- Asan Medical Center (KR)
- Pusan National University Hospital (KR)
- Inje University (KR)
- Jeonbuk National University Hospital (KR)
- Masonic Medical Research Laboratory (US)
- Corresponding author
- Nam, G.-B.
- Antzelevitch, C.
- Venue
- European Heart Journal
- Publisher
- Oxford University Press (OUP)
- Published
- 2009-10-29
- Volume
- 31
- Issue
- 3
- Pages
- 330-339
- ISSN
- 0195-668X (ISSN-L)
- 1522-9645
- PMC
- PMC2814221
- OpenAlex
- W2050644934
- Cited by
- 198
- References
- 30
- Citations by year
- 2026: 3 · 2025: 3 · 2024: 4 · 2023: 4 · 2022: 8 · 2021: 3 · 2020: 10 · 2019: 5 · 2018: 10 · 2017: 17 · 2016: 19 · 2015: 11 · 2014: 16 · 2013: 32 · 2012: 22
- FWCI
- 11.21
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- European Heart Journal (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- HighWire Press Open Archive (submittedVersion)
- Funders
- National Institutes of Health (HL 47678)
- National Heart, Lung, and Blood Institute (HL-47678, R01HL047678)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac electrophysiology and arrhythmias
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Arrhythmias and Treatments
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Effects of Exercise
- Keywords
- ventricular fibrillation, early repolarization, Brugada syndrome, electrical storm, J wave, premature ventricular contractions, coupling interval, sudden cardiac death, implantable cardioverter-defibrillator shocks, ventricular tachycardia
- MeSH terms
- Adult, Aged, Cardiac Pacing, Artificial, Cardiotonic Agents, Electrocardiography, Female, Humans, Isoproterenol, Male, Middle Aged, Ventricular Fibrillation, Case-Control Studies, Brugada Syndrome, Young Adult
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