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Cited by 362

The DOI matches its Crossref record; 39 of the 39 references it cites were found in a registry or an index.

Atrial fibrillation in heart failure: what should we do?

Open access
Kotecha, Dipak, Piccini, Jonathan P.·2015·European Heart Journal

Abstract

Heart failure (HF) and atrial fibrillation (AF) are two conditions that are likely to dominate the next 50 years of cardiovascular (CV) care. Both are increasingly prevalent and associated with high morbidity, mortality, and healthcare cost. They are closely inter-related with similar risk factors and shared pathophysiology. Patients with concomitant HF and AF suffer from even worse symptoms and poorer prognosis, yet evidence-based evaluation and management of this group of patients is lacking. In this review, we evaluate the common mechanisms for the development of AF in HF patients and vice versa, focusing on the evidence for potential treatment strategies. Recent data have suggested that these patients may respond differently than those with HF or AF alone. These results highlight the clear clinical need to identify and treat according to best evidence, in order to prevent adverse outcomes and reduce the huge burden that HF and AF are expected to have on global healthcare systems in the future. We propose an easy-to-use clinical mnemonic to aid the initial management of newly discovered concomitant HF and AF, the CAN-TREAT HFrEF + AF algorithm (Cardioversion if compromised; Anticoagulation unless contraindication; Normalize fluid balance; Target initial heart rate <110 b.p.m.; Renin-angiotensin-aldosterone modification; Early consideration of rhythm control; Advanced HF therapies; Treatment of other CV disease).

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Metadata

Authors
Kotecha, D., & Piccini, J. P.
Venue
European Heart Journal
Published
2015-09-28
Volume
36
Issue
46
Pages
ehv513
ISSN
  • 0195-668X (ISSN-L)
  • 1522-9645
OpenAlex
W2219147369
Cited by
362
References
39
FWCI
21.86
Type
journal article
Language
en
Open access
hybrid

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CoChat. (2026). Citation check: Atrial fibrillation in heart failure: what should we do? https://app.cochat.ai/papers/10.1093/eurheartj/ehv513
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Kotecha, D., & Piccini, J. P. (2015). Atrial fibrillation in heart failure: what should we do? European Heart Journal. https://doi.org/10.1093/eurheartj/ehv513

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Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.