The DOI matches its Crossref record; 23 of the 23 references it cites were found in a registry or an index.
Impact of treatment delay on mortality in ST-segment elevation myocardial infarction (STEMI) patients presenting with and without haemodynamic instability: results from the German prospective, multicentre FITT-STEMI trial
Open accessAbstract
Aims: The aim of this study was to investigate the effect of contact-to-balloon time on mortality in ST-segment elevation myocardial infarction (STEMI) patients with and without haemodynamic instability. Methods and results: Using data from the prospective, multicentre Feedback Intervention and Treatment Times in ST-Elevation Myocardial Infarction (FITT-STEMI) trial, we assessed the prognostic relevance of first medical contact-to-balloon time in n = 12 675 STEMI patients who used emergency medical service transportation and were treated with primary percutaneous coronary intervention (PCI). Patients were stratified by cardiogenic shock (CS) and out-of-hospital cardiac arrest (OHCA). For patients treated within 60 to 180 min from the first medical contact, we found a nearly linear relationship between contact-to-balloon times and mortality in all four STEMI groups. In CS patients with no OHCA, every 10-min treatment delay resulted in 3.31 additional deaths in 100 PCI-treated patients. This treatment delay-related increase in mortality was significantly higher as compared to the two groups of OHCA patients with shock (2.09) and without shock (1.34), as well as to haemodynamically stable patients (0.34, P < 0.0001). Conclusions: In patients with CS, the time elapsing from the first medical contact to primary PCI is a strong predictor of an adverse outcome. This patient group benefitted most from immediate PCI treatment, hence special efforts to shorten contact-to-balloon time should be applied in particular to these high-risk STEMI patients. Clinical Trial Registration: NCT00794001.
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Ibanez, B., James, S., Agewall, S., Antunes, M. J., Bucciarelli-Ducci, C., Bueno, H., Caforio, A. L. P., Crea, F., Goudevenos, J. A., Halvorsen, S., et al. (2018) · European Heart Journal · doi:10.1093/eurheartj/ehx393 · Cited by 9,728
Early Revascularization in Acute Myocardial Infarction Complicated by Cardiogenic Shock
Hochman, J. S., Sleeper, L. A., Webb, J. G., Sanborn, T. A., White, H. D., Talley, J. D., Buller, C. E., Jacobs, A. K., Slater, J. N., Col, J., et al. (1999) · New England Journal of Medicine · doi:10.1056/nejm199908263410901 · Cited by 3,131
2013 ACCF/AHA Guideline for the Management of ST-Elevation Myocardial Infarction: Executive Summary
O'Gara, P. T., Kushner, F. G., Ascheim, D. D., Casey, D. E., Chung, M. K., de Lemos, J. A., Ettinger, S. M., Fang, J. C., Fesmire, F. M., Franklin, B. A., et al. (2013) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2012.11.018 · Cited by 1,772
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Strategies for Reducing the Door-to-Balloon Time in Acute Myocardial Infarction
Bradley, E. H., Herrin, J., Wang, Y., Barton, B. A., Webster, T. R., Mattera, J. A., Roumanis, S. A., Curtis, J. P., Nallamothu, B. K., Magid, D. J., et al. (2006) · New England Journal of Medicine · doi:10.1056/nejmsa063117 · Cited by 839
McNamara, R. L., Wang, Y., Herrin, J., Curtis, J. P., Bradley, E. H., Magid, D. J., Peterson, E. D., Blaney, M., Frederick, P. D., & Krumholz, H. M. (2006) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2005.12.072 · Cited by 806
Ibanez, B., James, S. K., Agewall, S., Antunes, M. J., Bucciarelli‐Ducci, C., Bueno, H., Caforio, A. L. P., Crea, F., Goudevenos, J. A., Halvorsen, S., et al. (2018) · Open Access CRIS of the University of Bern · doi:10.7892/boris.111068 · Cited by 799
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One-Year Survival Following Early Revascularization for Cardiogenic Shock
Hochman, J. S. (2001) · JAMA · doi:10.1001/jama.285.2.190 · Cited by 679
Cited by
2018 ESC/EACTS guidelines on myocardial revascularization
Neumann, F.-J., Sousa-Uva, M., Ahlsson, A., Alfonso, F., Banning, A. P., Benedetto, U., Byrne, R. A., Collet, J.-P., Falk, V., Head, S. J., et al. (2019) · European Heart Journal · doi:10.1093/eurheartj/ehy394 · Cited by 7,167
2018 ESC/EACTS Guidelines on myocardial revascularization
Neumann, F.-J., Sousa-Uva, M., Ahlsson, A., Alfonso, F., Banning, A. P., Benedetto, U., Byrne, R. A., Collet, J.-P., Falk, V., Head, S. J., et al. (2019) · EuroIntervention · doi:10.4244/eijy19m01_01 · Cited by 1,259
2018 ESC/EACTS Guidelines on myocardial revascularization
Sousa-Uva, M., Neumann, F.-J., Ahlsson, A., Alfonso, F., Banning, A. P., Benedetto, U., Byrne, R. A., Collet, J.-P., Falk, V., Head, S. J., et al. (2019) · European Journal of Cardio-Thoracic Surgery · doi:10.1093/ejcts/ezy289 · Cited by 989
Rao, S. V., O’Donoghue, M. L., Ruel, M., Rab, T., Tamis-Holland, J. E., Alexander, J. H., Baber, U., Baker, H., Cohen, M. G., Cruz-Ruiz, M., et al. (2025) · Circulation · doi:10.1161/cir.0000000000001309 · Cited by 625
Early prediction of circulatory failure in the intensive care unit using machine learning
Hyland, S. L., Faltys, M., Hüser, M., Lyu, X., Gumbsch, T., Esteban, C., Bock, C., Horn, M., Moor, M., Rieck, B., et al. (2020) · Nature Medicine · doi:10.1038/s41591-020-0789-4 · Cited by 477
Metadata
- Authors
- Scholz, K. H., Maier, S. K. G., Maier, L. S., Lengenfelder, B., Jacobshagen, C., Jung, J., Fleischmann, C., Werner, G. S., Olbrich, H. G., Ott, R., Mudra, H., Seidl, K., Schulze, P. C., Weiss, C., Haimerl, J., Friede, T., & Meyer, T.
- Venue
- European Heart Journal
- Publisher
- Oxford University Press (OUP)
- Published
- 2018-02-14
- Volume
- 39
- Issue
- 13
- Pages
- 1065-1074
- ISSN
- 0195-668X (ISSN-L)
- 1522-9645
- OpenAlex
- W2793495719
- Cited by
- 375
- References
- 23
- FWCI
- 32.51
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Scholz, K. H., Maier, S. K. G., Maier, L. S., Lengenfelder, B., Jacobshagen, C., Jung, J., Fleischmann, C., Werner, G. S., Olbrich, H. G., Ott, R., Mudra, H., Seidl, K., Schulze, P. C., Weiss, C., Haimerl, J., Friede, T., & Meyer, T. (2018). Impact of treatment delay on mortality in ST-segment elevation myocardial infarction (STEMI) patients presenting with and without haemodynamic instability: results from the German prospective, multicentre FITT-STEMI trial. European Heart Journal. https://doi.org/10.1093/eurheartj/ehy004
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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