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Cited by 237Cardiovascular Function and Risk FactorsHemodynamic Monitoring and TherapyCardiac pacing and defibrillation studies

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Invasive left ventricle pressure–volume analysis: overview and practical clinical implications

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Bastos, Marcelo B, Burkhoff, Daniel, Maly, Jiri, Daemen, Joost, den Uil, Corstiaan A, Ameloot, Koen, Lenzen, Mattie, Mahfoud, Felix, Zijlstra, Felix, Schreuder, Jan J, Van Mieghem, Nicolas M·2020·European Heart Journal
DOI 10.1093/eurheartj/ehz552PMC PMC7084193
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Abstract

Ventricular pressure–volume (PV) analysis is the reference method for the study of cardiac mechanics. Advances in calibration algorithms and measuring techniques brought new perspectives for its application in different research and clinical settings. Simultaneous PV measurement in the heart chambers offers unique insights into mechanical cardiac efficiency. Beat to beat invasive PV monitoring can be instrumental in the understanding and management of heart failure, valvular heart disease, and mechanical cardiac support. This review focuses on intra cardiac left ventricular PV analysis principles, interpretation of signals, and potential clinical applications.

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  • The PV loops were characterized by two distinct filling and ejection phases separated by rapid vertical isovolumetric phases, as observed in the classic PV loop of the native ventricle.

    “Similarly, the PV loops were characterized by two distinct filling and ejection phases that are separated by rapid vertical isovolumetric phases (Fig. 4G), as it is observed in the classic PV loop of the native ventricle (15).”

    From Engineering a living cardiac pump on a chip using high-precision fabrication (2022) · cites this paper as [15]

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Metadata

Authors
Bastos, M. B., Burkhoff, D., Maly, J., Daemen, J., den Uil, C. A., Ameloot, K., Lenzen, M., Mahfoud, F., Zijlstra, F., Schreuder, J. J., & Van Mieghem, N. M.
Affiliations
  • Erasmus MC (NL)
  • Cardiovascular Research Foundation (US)
  • Department of Cardiac and Transplant Surgery , IKEM, Prague, Czech Republic
  • Universitätsklinikum des Saarlandes (DE)
  • Department of Cardiology, Thoraxcenter, Erasmus University Medical Centre , Office Nt 645, Dr Molewaterplein 40 3015 GD, Rotterdam, The Netherlands
ORCID
Venue
European Heart Journal
Publisher
Oxford University Press (OUP)
Published
2019-08-21
Volume
41
Issue
12
Pages
1286-1297
ISSN
  • 0195-668X (ISSN-L)
  • 1522-9645
DOI
10.1093/eurheartj/ehz552
PMC
PMC7084193
OpenAlex
W2969787468
Cited by
237
References
0
Citations by year
2026: 34 · 2025: 36 · 2024: 46 · 2023: 43 · 2022: 37 · 2021: 25 · 2020: 15
FWCI
3.48
Type
journal article
Language
en
Open access
Licence
Locations
  • European Heart Journal (publishedVersion, cc-by-nc)
  • PubMed Central (publishedVersion, cc-by-nc)
  • PubMed (publishedVersion)
  • EUR Research Repository (Erasmus University Rotterdam) (publishedVersion, other-oa)
  • EUR Research Repository (Erasmus University Rotterdam) (submittedVersion, other-oa)
  • RePub (Erasmus University Rotterdam) (submittedVersion, other-oa)
  • RePub (Erasmus University Rotterdam) (submittedVersion)
Topics
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Function and Risk Factors
  • Health Sciences › Medicine › Surgery › Hemodynamic Monitoring and Therapy
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac pacing and defibrillation studies
Keywords
cardiac mechanics, invasive hemodynamic monitoring, heart failure, valvular heart disease, mechanical circulatory support
MeSH terms
Cardiac Volume, Heart, Heart Failure, Heart Ventricles, Humans, Myocardial Contraction, Stroke Volume, Ventricular Function, Left, Ventricular Pressure

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