Cited by 98Cardiac pacing and defibrillation studiesCardiac Arrest and ResuscitationCardiac Health and Mental Health

The European CRT Survey: 1 year (9–15 months) follow-up results

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Bogale, Nigussie, Priori, Silvia, Cleland, John G.F., Brugada, Josep, Linde, Cecilia, Auricchio, Angelo, van Veldhuisen, Dirk J., Limbourg, Tobias +9 more·2012·European Journal of Heart Failure

Abstract

AIMS: The European CRT Survey is a joint initiative of the Heart Failure Association (HFA) and the European Heart Rhythm Association (EHRA) of the European Society of Cardiology evaluating the contemporary implantation practice of cardiac resynchronization therapy (CRT) in Europe. METHODS AND RESULTS: Patients who had a successful CRT implantation were enrolled from 141 centres in 13 countries between November 2008 and June 2009. Baseline demographics, clinical and implantation data were collected, with a follow-up of ∼1 year (9-15 months). The current report describes clinical outcomes including symptom severity, cardiovascular (CV) hospitalization, and survival. A total of 2438 patients were enrolled, and follow-up data were acquired from 2111 patients (87%). The population included important groups of patients poorly represented in randomized controlled trials, including very elderly patients and those with prior device implantation, atrial fibrillation, and/or QRS duration <120 ms. Investigators reported substantial improvement in New York Heart Association (NYHA) functional class at follow-up. Patient self-assessment indicated that 81% of the patients felt improved, 16% reported no change, and 4% reported deterioration. During follow-up, 207 (10%) patients died, 346 (16%) had a CV hospitalization, and 501 (24%) died or had CV hospitalization. Worse NYHA functional class, atrial fibrillation, ischaemic aetiology, and device type (CRT-P, i.e. CRT alone) were associated with poorer survival. Women had a better outcome, as did patients who had a CRT-D (with an implantable cardioverter defibrillator function) device. CONCLUSIONS: Outcomes including death and hospitalization in this European CRT survey were consistent with results from clinical trials of CRT. At 1 year follow-up, most patients who received a CRT device considered their symptoms improved compared with their pre-implant assessment. Although prospective, this is an observational study of successful CRT implantations, and outcomes in subgroup analyses must be interpreted with appropriate conservatism.

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  • Device therapies such as cardiac resynchronization therapy and left ventricular assist devices are associated with reduced dyspnoea.

    “Device therapies such as cardiac resynchronization therapy and left ventricular assist devices are also associated with reduced dyspnoea. 58 , 59”

    From Prioritizing symptom management in the treatment of chronic heart failure (2020) · cites this paper as [58]

    The Clinical status section reports improved NYHA functional class after CRT implantation, with 81% of patients saying they felt better at follow-up. This supports an association with symptom improvement, but the paper does not report dyspnoea separately or assess left ventricular assist devices; the latter may be covered by the sentence’s other citation. (LLM, conf=0.82)

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Research works printed but not linked: 3

  1. Cleland JG, Tavazzi L, Daubert JC, Tageldien A, Freemantle N. Cardiac resynchro- nization therapy: are modern myths preventing appropriate use? J Am Coll Cardiol 2009;53:608 -611.
  2. Granger CB, Gersh BJClinical trials registries in cardiovascular disease: competi- tive or complementary? Eur Heart J 2010;31:520 -521.
  3. Yao G, Freemantle N, Calvert MJ, Bryan S, Daubert JC, Cleland JG. The long-term cost-effectiveness of cardiac resynchronization therapy with or without an implantable cardioverter-defibrillator. Eur Heart J 2007;28:42-51.

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Authors
Bogale, N., Priori, S., Cleland, J. G. F., Brugada, J., Linde, C., Auricchio, A., van Veldhuisen, D. J., Limbourg, T., Gitt, A., Gras, D., Stellbrink, C., Gasparini, M., Metra, M., Derumeaux, G., Gadler, F., Buga, L., & Dickstein, K.
Affiliations
  • Stavanger University Hospital (NO)
  • State University of New York (US)
  • University of Hull (GB)
  • Thorax Institute, Hospital Clinic, University of Barcelona , Barcelona ,
  • Karolinska University Hospital (SE)
  • Istituto Cardiocentro Ticino (CH)
  • University Medical Center Groningen , Groningen ,
  • Heidelberg University (DE)
  • Nouvelles Cliniques Nantaises (FR)
  • Klinikum Bielefeld (DE)
  • IRCCS Humanitas Research Hospital (IT)
  • University of Brescia (IT)
  • Université Claude Bernard Lyon I , Lyon ,
Corresponding author
Bogale, Nigussie
Venue
European Journal of Heart Failure
Published
2012-01-01
Volume
14
Issue
1
Pages
61-73
ISSN
  • 1388-9842 (ISSN-L)
  • 1879-0844
OpenAlex
W2146109661
Cited by
98
References
44
Citations by year
2026: 1 · 2024: 5 · 2023: 2 · 2022: 2 · 2021: 2 · 2020: 4 · 2019: 5 · 2018: 9 · 2017: 8 · 2016: 9 · 2015: 13 · 2014: 16 · 2013: 17 · 2012: 5
FWCI
8.33
Type
journal article
Language
en
Open access
Locations
  • European Journal of Heart Failure (publishedVersion)
  • PubMed (publishedVersion)
  • University of Groningen research database (University of Groningen / Centre for Information Technology) (publishedVersion)
  • NORA - Norwegian Open Research Archives (submittedVersion, other-oa)
  • ENLIGHTEN (Jurnal Bimbingan dan Konseling Islam) (submittedVersion)
  • Institutional Research Information System (Università degli Studi di Brescia) (submittedVersion)
  • Archivio Istituzionale della Ricerca - Università Vita-Salute San Raffaele (submittedVersion)
  • Zurich Open Repository and Archive (University of Zurich) (submittedVersion)
  • University of Groningen research database (University of Groningen / Centre for Information Technology) (submittedVersion)
Funders
National Institute for Health and Care Research (NF-SI-0611-10227)
Topics
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac pacing and defibrillation studies
  • Health Sciences › Medicine › Emergency Medicine › Cardiac Arrest and Resuscitation
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Health and Mental Health
Keywords
cardiac resynchronization therapy, heart failure, NYHA functional class, cardiovascular hospitalization, survival, atrial fibrillation, CRT-P, CRT-D, implantable cardioverter-defibrillator, QRS duration, sex differences, implantation outcomes
MeSH terms
Aged, Atrial Fibrillation, Data Collection, Europe, Female, Follow-Up Studies, Heart Failure, Heart Function Tests, Hospitalization, Humans, Male, Middle Aged, Outcome and Process Assessment, Health Care, Risk Factors, Severity of Illness Index, Multicenter Studies as Topic, Survival Analysis, Randomized Controlled Trials as Topic, Treatment Outcome, Risk Assessment, Cardiac Resynchronization Therapy, Cardiac Resynchronization Therapy Devices

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