Cited by 37Cardiac Arrhythmias and TreatmentsCongenital Heart Disease StudiesAtrial Fibrillation Management and Outcomes

Very long-term results of electroanatomic-guided radiofrequency ablation of atrial arrhythmias in patients with surgically corrected atrial septal defect

Scaglione, Marco, Caponi, Domenico, Ebrille, Elisa, Di Donna, Paolo, Di Clemente, Francesca, Battaglia, Alberto, Raimondo, Cristina, Appendino, Manuela +1 more·2014·EP Europace

Abstract

AIMS: Atrial tachycardias are common after repair of atrial septal defect (ASD). Although ablation has shown promising results in the short and mid-term follow-up, little data regarding the very long-term success exist. Our aim was to assess very long-term follow-up in patients who have undergone electroanatomic-guided radiofrequency (RF) ablation of late-onset atrial arrhythmias after ASD surgery. METHODS AND RESULTS: Forty-six consecutive patients with surgically repaired ASD were referred for atrial tachycardia ablation. Electrophysiological (EP) study and ablation procedure with the aid of an electroanatomic mapping (EAM) system were performed. Mean age was 49 ± 13 years (females 61%). The presenting arrhythmias were typical atrial flutter (48%), atypical atrial flutter (35%), and atrial tachycardia (17%). In 41% of patients, atrial fibrillation was also present. The EP study showed a right atrial macroreentrant circuit in all the patients. In 12 of 46 (26%), the circuit was localized in the cavo-tricuspid isthmus, whereas in the remaining 34 patients (74%) was atriotomy-dependent. Acute success was 100%. Clinical arrhythmia recurred in 24% of the patients. Nine patients underwent a second and two a third ablation procedure, reaching an overall efficacy of 87% (40 of 46) at a mean follow-up of 7.3 ± 3.8 years since the last procedure. With antiarrhythmic drugs the success rate increased to 96% (44 of 46). No complications occurred. CONCLUSION: In patients with surgically corrected ASD, EAM-guided RF ablation of late-onset macroreentrant atrial arrhythmias demonstrated a high success rate in a very long-term follow-up. Therefore, RF ablation could be considered early in the management of late-onset macroreentrant atrial tachycardias.

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Crossref · 10.1093/europace/euu076

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Authors
Scaglione, M., Caponi, D., Ebrille, E., Di Donna, P., Di Clemente, F., Battaglia, A., Raimondo, C., Appendino, M., & Gaita, F.
Affiliations
  • Azienda Sanitaria Locale di Asti (IT)
  • University of Turin (IT)
Corresponding author
Scaglione, Marco
Venue
EP Europace
Published
2014-05-19
Volume
16
Issue
12
Pages
1800-1807
ISSN
  • 1099-5129 (ISSN-L)
  • 1532-2092
OpenAlex
W2081316841
Cited by
37
References
23
Citations by year
2025: 4 · 2024: 1 · 2023: 1 · 2022: 1 · 2021: 3 · 2020: 1 · 2019: 3 · 2018: 5 · 2017: 4 · 2016: 6 · 2015: 8
FWCI
4.14
Type
journal article
Language
en
Open access
closed
Locations
  • EP Europace (publishedVersion)
  • PubMed (publishedVersion)
  • Institutional Research Information System University of Turin (University of Turin) (submittedVersion)
Topics
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Arrhythmias and Treatments
  • Health Sciences › Medicine › Epidemiology › Congenital Heart Disease Studies
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Atrial Fibrillation Management and Outcomes
Keywords
atrial septal defect, atrial tachycardia, atrial flutter, atrial fibrillation, electroanatomical mapping, radiofrequency ablation, cavotricuspid isthmus, antiarrhythmic drugs, arrhythmia recurrence
MeSH terms
Atrial Fibrillation, Atrial Flutter, Female, Heart Septal Defects, Atrial, Humans, Longitudinal Studies, Male, Middle Aged, Treatment Outcome, Catheter Ablation, Body Surface Potential Mapping, Surgery, Computer-Assisted

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