The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
THE AGE OF A NEUTRAL MUTANT PERSISTING IN A FINITE POPULATION
Open accessAbstract
Formulae for the mean and the mean square age of a neutral allele which is segregating with frequency x in a population of effective size Ne have been obtained using the diffusion equation method, for the case of 4Nev<1 where v is the mutation rate. It has been shown that the average ages of neutral alleles, even if their frequencies are relatively low, are quite old. For example, a neutral mutant whose current frequency is 10% has the expected age roughly equal to the effective population size Ne and the standard deviation 1.4Ne (in generations), assuming that this mutant has increased by random drift from a very low frequency. Also, formulae for the mean "first arrival time" of a neutral mutant to a certain frequency x have been presented. In addition, a new, approximate method has been developed which enables us to obtain the condition under which frequencies of "rare" polymorphic alleles among local populations are expected to be uniform if the alleles are selectively neutral.—It was concluded that exchange of only a few individuals on the average between adjacent colonies per generation is enough to bring about such a uniformity of frequencies.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“As predicted by classical theory (29), humans have limited genetic variation: The heterozygosity rate for single-nucleotide polymorphisms (SNPs) is ~1 in 1000 bases (30–32).”
From Genetic Mapping in Human Disease (2008) · cites this paper as [29]
Citations
Cites
THE NUMBER OF ALLELES THAT CAN BE MAINTAINED IN A FINITE POPULATION
Kimura, M., & Crow, J. F. (1964) · Genetics · doi:10.1093/genetics/49.4.725 · Cited by 2,621
Self-citationDiffusion models in population genetics
Kimura, M. (1964) · Journal of Applied Probability · doi:10.2307/3211856 · Cited by 773
Self-citationSELECTION FOR HETEROZYGOTES IN SMALL POPULATIONS
Robertson, A. (1962) · Genetics · doi:10.1093/genetics/47.9.1291 · Cited by 258
Pattern of neutral polymorphism in a geographically structured population
Kimura, M., & Maruyama, T. (1971) · Genetics Research · doi:10.1017/s0016672300012520 · Cited by 183
Self-citationDevelopment of associative overdominance through linkage disequilibrium in finite populations
Ohta, T., & Kimura, M. (1970) · Genetics Research · doi:10.1017/s0016672300002391 · Cited by 111
Self-citation
Flagged first, then by citations
Cited by
Sorted by citations
Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels
Saxena, R., Voight, B. F., Lyssenko, V., Burtt, N. P., de Bakker, P. I. W., Chen, H., Roix, J. J., Kathiresan, S., Hirschhorn, J. N., Daly, M. J., et al. (2007) · Science · doi:10.1126/science.1142358 · Cited by 2,843
Worldwide Human Relationships Inferred from Genome-Wide Patterns of Variation
Li, J. Z., Absher, D. M., Tang, H., Southwick, A. M., Casto, A. M., Ramachandran, S., Cann, H. M., Barsh, G. S., Feldman, M. W., Cavalli-Sforza, L. L., et al. (2008) · Science · doi:10.1126/science.1153717 · Cited by 1,915
Genetic Mapping in Human Disease
Altshuler, D., Daly, M. J., & Lander, E. S. (2008) · Science · doi:10.1126/science.1156409 · Cited by 1,452
Analysis of 6,515 exomes reveals the recent origin of most human protein-coding variants
Fu, W., O’Connor, T. D., Jun, G., Kang, H. M., Abecasis, G. R., Leal, S. M., Gabriel, S., Rieder, M. J., Altshuler, D., Shendure, J., et al. (2012) · Nature · doi:10.1038/nature11690 · Cited by 969
Line-of-descent and genealogical processes, and their applications in population genetics models
Tavaré, S. (1984) · Theoretical Population Biology · doi:10.1016/0040-5809(84)90027-3 · Cited by 581
Metadata
- Authors
- Kimura, M., & Ohta, T.
- Affiliations
- National Institute of Genetics (JP)
- Venue
- Genetics
- Publisher
- Oxford University Press (OUP)
- Published
- 1973-09-01
- Volume
- 75
- Issue
- 1
- Pages
- 199-212
- ISSN
- 0016-6731 (ISSN-L)
- 1943-2631
- OpenAlex
- W2144162032
- Cited by
- 241
- References
- 5
- Citations by year
- 2026: 2 · 2025: 12 · 2024: 8 · 2023: 9 · 2022: 3 · 2021: 8 · 2020: 6 · 2019: 8 · 2018: 4 · 2017: 10 · 2016: 8 · 2015: 10 · 2014: 11 · 2013: 7 · 2012: 10
- FWCI
- 3.43
- Type
- journal article
- Language
- en
- Open access
- green
- europepmc.org
- Licence
- academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model (vor)
- Locations
- Genetics (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Evolution and Genetic Dynamics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic diversity and population structure
- Physical Sciences › Mathematics › Mathematical Physics › Stochastic processes and statistical mechanics
- Keywords
- effective population size, mutation rate, genetic drift, diffusion equation, first arrival time, neutral selection
- MeSH terms
- Analysis of Variance, Gene Frequency, Genetics, Population, Mathematics, Mutation, Polymorphism, Genetic, Time Factors
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
