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THE DNA OF CAENORHABDITIS ELEGANS
Open accessAbstract
Chemical analysis and a study of renaturation kinetics show that the nematode, Caenorhabditis elegans, has a haploid DNA content of 8 x IO7 base pairs (20 times the genome of E. coli). Eighty-three percent of the DNA sequences are unique. The mean base composition is 36% GC; a small component, containing the rRNA cistrons, has a base composition of 51% GC. The haploid genome contains about 300 genes for 4s RNA, 110 for 5s RNA, and 55 for (18 + 28)S RNA.
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Cited by
Drake, J. W., Charlesworth, B., Charlesworth, D., & Crow, J. F. (1998) · Genetics · doi:10.1093/genetics/148.4.1667 · Cited by 1,932
The dauerlarva, a post-embryonic developmental variant of the nematode Caenorhabditis elegans
Cassada, R. C., & Russell, R. L. (1975) · Developmental Biology · doi:10.1016/0012-1606(75)90109-8 · Cited by 894
Serotonin and Octopamine in the Nematode Caenorhabditis elegans
Horvitz, H. R., Chalfie, M., Trent, C., Sulston, J. E., & Evans, P. D. (1982) · Science · doi:10.1126/science.6805073 · Cited by 580
Self-citationTDP-43 represses cryptic exon inclusion in the FTD-ALS gene UNC13A
Ma, X. R., Prudencio, M., Koike, Y., Vatsavayai, S. C., Kim, G., Harbinski, F., Briner, A., Rodriguez, C. M., Guo, C., Akiyama, T., et al. (2022) · Nature · doi:10.1038/s41586-022-04424-7 · Cited by 574
Dimensionality and Dynamics in the Behavior of C. elegans
Stephens, G. J., Johnson-Kerner, B., Bialek, W., & Ryu, W. S. (2008) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1000028 · Cited by 509
Metadata
- Authors
- Sulston, J. E., & Brenner, S.
- Venue
- Genetics
- Publisher
- Oxford University Press (OUP)
- Published
- 1974-05-01
- Volume
- 77
- Issue
- 1
- Pages
- 95-104
- ISSN
- 0016-6731 (ISSN-L)
- 1943-2631
- OpenAlex
- W2115708583
- Cited by
- 584
- References
- 0
- FWCI
- 17.38
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Sulston, J. E., & Brenner, S. (1974). THE DNA OF CAENORHABDITIS ELEGANS. Genetics. https://doi.org/10.1093/genetics/77.1.95
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
