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Cited by 580

The DOI matches its Crossref record; 19 of the 19 references it cites were found in a registry or an index.

Serotonin and Octopamine in the Nematode Caenorhabditis elegans

Horvitz, H. Robert, Chalfie, Martin, Trent, Carol, Sulston, John E., Evans, Peter D.·1982·Science

Abstract

The biogenic amines serotonin and octopamine are present in the nematode Caenorhabditis elegans . Serotonin, detected histochemically in whole mounts, is localized in two pharyngeal neurons that appear to be neurosecretory. Octopamine, identified radioenzymatically in crude extracts, probably is also localized in a few neurons. Exogenous serotonin and octopamine elicit specific and opposite behavioral responses in Caenorhabditis elegans , suggesting that these compounds function physiologically as antagonists.

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Crossref · 10.1126/science.6805073

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Metadata

Authors
Horvitz, H. R., Chalfie, M., Trent, C., Sulston, J. E., & Evans, P. D.
Venue
Science
Published
1982-05-28
Volume
216
Issue
4549
Pages
1012-1014
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
OpenAlex
W2092111364
Cited by
580
References
19
FWCI
1.33
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Serotonin and Octopamine in the Nematode Caenorhabditis elegans. https://app.cochat.ai/papers/10.1126/science.6805073
The paper
Horvitz, H. R., Chalfie, M., Trent, C., Sulston, J. E., & Evans, P. D. (1982). Serotonin and Octopamine in the Nematode Caenorhabditis elegans. Science. https://doi.org/10.1126/science.6805073

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.