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ESTIMATION OF AVERAGE HETEROZYGOSITY AND GENETIC DISTANCE FROM A SMALL NUMBER OF INDIVIDUALS
Abstract
The magnitudes of the systematic biases involved in sample heterozygosity and sample genetic distances are evaluated, and formulae for obtaining unbiased estimates of average heterozygosity and genetic distance are developed. It is also shown that the number of individuals to be used for estimating average heterozygosity can be very small if a large number of loci are studied and the average heterozygosity is low. The number of individuals to be used for estimating genetic distance can also be very small if the genetic distance is large and the average heterozygosity of the two species compared is low.
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Cited by
SKREDE, I., EIDESEN, P. B., PORTELA, R. P., & BROCHMANN, C. (2006) · Molecular Ecology · doi:10.1111/j.1365-294x.2006.02908.x · Cited by 2,746
Inference of population splits and mixtures from genome-wide allele frequency data
Pickrell, J. K., & Pritchard, J. K. (2012) · PLoS Genetics · doi:10.1371/journal.pgen.1002967 · Cited by 2,731
Waits, L. P., Luikart, G., & Taberlet, P. (2001) · Molecular Ecology · doi:10.1046/j.1365-294x.2001.01185.x · Cited by 1,437
Waples, R. S., & Do, C. (2010) · Evolutionary Applications · doi:10.1111/j.1752-4571.2009.00104.x · Cited by 991
Putting the ‘landscape’ in landscape genetics
Storfer, A., Murphy, M. A., Evans, J. S., Goldberg, C. S., Robinson, S., Spear, S. F., Dezzani, R., Delmelle, E., Vierling, L., & Waits, L. P. (2007) · Heredity · doi:10.1038/sj.hdy.6800917 · Cited by 938
Metadata
- Authors
- Nei, M.
- Venue
- Genetics
- Publisher
- Oxford University Press (OUP)
- Published
- 1978-07-20
- Volume
- 89
- Issue
- 3
- Pages
- 583-590
- ISSN
- 0016-6731 (ISSN-L)
- 1943-2631
- OpenAlex
- W2142644281
- Cited by
- 11,381
- References
- 0
- FWCI
- 8.86
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: ESTIMATION OF AVERAGE HETEROZYGOSITY AND GENETIC DISTANCE FROM A SMALL NUMBER OF INDIVIDUALS. https://app.cochat.ai/papers/10.1093/genetics/89.3.583
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- Nei, M. (1978). ESTIMATION OF AVERAGE HETEROZYGOSITY AND GENETIC DISTANCE FROM A SMALL NUMBER OF INDIVIDUALS. Genetics. https://doi.org/10.1093/genetics/89.3.583
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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