Inference of population splits and mixtures from genome-wide allele frequency data
Open accessAbstract
Many aspects of the historical relationships between populations in a species are reflected in genetic data. Inferring these relationships from genetic data, however, remains a challenging task. In this paper, we present a statistical model for inferring the patterns of population splits and mixtures in multiple populations. In our model, the sampled populations in a species are related to their common ancestor through a graph of ancestral populations. Using genome-wide allele frequency data and a Gaussian approximation to genetic drift, we infer the structure of this graph. We applied this method to a set of 55 human populations and a set of 82 dog breeds and wild canids. In both species, we show that a simple bifurcating tree does not fully describe the data; in contrast, we infer many migration events. While some of the migration events that we find have been detected previously, many have not. For example, in the human data, we infer that Cambodians trace approximately 16% of their ancestry to a population ancestral to other extant East Asian populations. In the dog data, we infer that both the boxer and basenji trace a considerable fraction of their ancestry (9% and 25%, respectively) to wolves subsequent to domestication and that East Asian toy breeds (the Shih Tzu and the Pekingese) result from admixture between modern toy breeds and "ancient" Asian breeds. Software implementing the model described here, called TreeMix, is available at http://treemix.googlecode.com.
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Gene flow from helmeted guinea fowl to domestic helmeted guinea fowl in Sudan was indicated in TreeMix when m = 1 in 99.9% of the bootstrap replicates.
“Gene flow from the HGF to domestic HGF in Sudan was indicated in the TreeMix (Pickrell and Pritchard 2012) when m = 1 (supplementary fig. S6, Supplementary Material online) in 99.9% of the bootstrap replicates.”
From Genomic Analyses Unveil Helmeted Guinea Fowl (<i>Numida meleagris</i>) Domestication in West Africa (2021) · cites this paper as Pickrell and Pritchard 2012
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The neighbor-joining method: a new method for reconstructing phylogenetic trees.
Saitou, N., & Nei, M. (1987) · Molecular Biology and Evolution · doi:10.1093/oxfordjournals.molbev.a040454 · Cited by 59,962 · see citing works
Inference of Population Structure Using Multilocus Genotype Data
Pritchard, J. K., Stephens, M., & Donnelly, P. (2000) · Genetics · doi:10.1093/genetics/155.2.945 · Cited by 33,871 · see citing works
Self-citationESTIMATION OF AVERAGE HETEROZYGOSITY AND GENETIC DISTANCE FROM A SMALL NUMBER OF INDIVIDUALS
Nei, M. (1978) · Genetics · doi:10.1093/genetics/89.3.583 · Cited by 11,499 · see citing works
Application of Phylogenetic Networks in Evolutionary Studies
Huson, D. H., & Bryant, D. (2005) · Molecular Biology and Evolution · doi:10.1093/molbev/msj030 · Cited by 8,751 · see citing works
Solving Least Squares Problems
Lawson, C. L., & Hanson, R. J. (1995) · doi:10.1137/1.9781611971217 · Cited by 7,103 · see citing works
Koller, D., & Friedman, N. (2009) · The MIT Press eBooks · Cited by 6,653 · see citing works
(2009) · Cited by 6,153 · see citing works
Population Structure and Eigenanalysis
Patterson, N., Price, A. L., & Reich, D. (2006) · PLoS Genetics · doi:10.1371/journal.pgen.0020190 · Cited by 5,280 · see citing works
A draft sequence of the Neandertal genome
Green, R. E., Krause, J., Briggs, A. W., Maricic, T., Stenzel, U., Kircher, M., Patterson, N., Li, H., Zhai, W., Fritz, M. H.-Y., et al. (2010) · Science · doi:10.1126/science.1188021 · Cited by 4,318 · see citing works
Mitochondrial DNA and human evolution
Cann, R. L., Stoneking, M., & Wilson, A. C. (1987) · Nature · doi:10.1038/325031a0 · Cited by 3,100 · see citing works
Wooding, S. (2004) · The American Journal of Human Genetics · doi:10.1086/383584 · Cited by 3,093 · see citing works
Genetic Structure of Human Populations
Rosenberg, N. A., Pritchard, J. K., Weber, J. L., Cann, H. M., Kídd, K. K., Анатольевич, Ж. Л., & Feldman, M. W. (2002) · Science · doi:10.1126/science.1078311 · Cited by 3,000 · see citing works
Self-citationApproximate Bayesian computation in population genetics
Beaumont, M. A., Zhang, W., & Balding, D. J. (2002) · Genetics · doi:10.1093/genetics/162.4.2025 · Cited by 2,932 · see citing works
Ancient Admixture in Human History
Patterson, N., Moorjani, P., Luo, Y., Mallick, S., Rohland, N., Zhan, Y., Genschoreck, T., Webster, T., & Reich, D. (2012) · Genetics · doi:10.1534/genetics.112.145037 · Cited by 2,848 · see citing works
Genome sequence, comparative analysis and haplotype structure of the domestic dog
members, B. S. P., Lindblad-Toh, K., Wade, C. M., Mikkelsen, T. S., Karlsson, E. K., Jaffe, D. B., Kamal, M., Clamp, M., Chang, J. L., Kulbokas, E. J., et al. (2005) · Nature · doi:10.1038/nature04338 · Cited by 2,568 · see citing works
Generating samples under a Wright–Fisher neutral model of genetic variation
Hudson, R. R. (2002) · Bioinformatics · doi:10.1093/bioinformatics/18.2.337 · Cited by 2,397 · see citing works
Phylogenetic analysis: models and estimation procedures
Winther, R. G. (2018) · Cambridge University Press eBooks · doi:10.1017/9781316276259.010 · Cited by 2,258 · see citing works
PHYLOGENETIC ANALYSIS: MODELS AND ESTIMATION PROCEDURES
Cavalli-Sforza, L. L., & Edwards, A. W. F. (1967) · Evolution · doi:10.1111/j.1558-5646.1967.tb03411.x · Cited by 2,243 · see citing works
Genetic history of an archaic hominin group from Denisova Cave in Siberia
Reich, D., Green, R. E., Kircher, M., Krause, J., Patterson, N., Durand, E. Y., Viola, B., Briggs, A. W., Stenzel, U., Johnson, P. L. F., et al. (2010) · Nature · doi:10.1038/nature09710 · Cited by 1,991 · see citing works
Worldwide Human Relationships Inferred from Genome-Wide Patterns of Variation
Li, J. Z., Absher, D. M., Tang, H., Southwick, A. M., Casto, A. M., Ramachandran, S., Cann, H. M., Barsh, G. S., Feldman, M. W., Cavalli-Sforza, L. L., et al. (2008) · Science · doi:10.1126/science.1153717 · Cited by 1,947 · see citing works
Gutenkunst, R. N., Hernandez, R. D., Williamson, S. H., & Bustamante, C. D. (2009) · PLoS Genetics · doi:10.1371/journal.pgen.1000695 · Cited by 1,906 · see citing works
Reconstructing Indian population history
Reich, D., Thangaraj, K., Patterson, N., Price, A. L., & Singh, L. (2009) · Nature · doi:10.1038/nature08365 · Cited by 1,674 · see citing works
DendroPy: a Python library for phylogenetic computing
Sukumaran, J., & Holder, M. T. (2010) · Bioinformatics · doi:10.1093/bioinformatics/btq228 · Cited by 1,637 · see citing works
Genes mirror geography within Europe
Novembre, J., Johnson, T., Bryc, K., Kutalik, Z., Boyko, A. R., Auton, A., Indap, A., King, K. S., Bergmann, S., Nelson, M. R., et al. (2008) · Nature · doi:10.1038/nature07331 · Cited by 1,479 · see citing works
Hey, J., & Nielsen, R. (2004) · Genetics · doi:10.1534/genetics.103.024182 · Cited by 1,434 · see citing works
Population genomics of domestic and wild yeasts
Liti, G., Carter, D. M., Moses, A. M., Warringer, J., Parts, L., James, S. A., Davey, R., Roberts, I. N., Burt, A., Koufopanou, V., et al. (2008) · Nature · doi:10.1038/nature07743 · Cited by 1,391 · see citing works
Testing for ancient admixture between closely related populations
Durand, E. Y., Patterson, N., Reich, D., & Slatkin, M. (2011) · Molecular Biology and Evolution · doi:10.1093/molbev/msr048 · Cited by 1,375 · see citing works
Phylogenetic Analysis: Models and Estimation Procedures
Cavalli-Sforza, L. L., & Edwards, A. W. F. (1967) · Evolution · doi:10.2307/2406616 · Cited by 1,216 · see citing works
Population growth of human Y chromosomes: a study of Y chromosome microsatellites.
Pritchard, J., Seielstad, M., Pérez-Lezaun, A., & Feldman, M. (1999) · Molecular biology and evolution · doi:10.1093/oxfordjournals.molbev.a026091 · Cited by 1,201 · see citing works
Self-citationInference of Population Structure using Dense Haplotype Data
Lawson, D. J., Hellenthal, G., Myers, S., & Falush, D. (2012) · PLoS Genetics · doi:10.1371/journal.pgen.1002453 · Cited by 1,188 · see citing works
Numerical recipes in C (2nd ed.): the art of scientific computing
Press, W. H., Teukolsky, S. A., Vetterling, W. T., & Flannery, B. P. (1992) · Cambridge University Press eBooks · Cited by 1,156 · see citing works
Beerli, P., & Felsenstein, J. (1999) · Genetics · doi:10.1093/genetics/152.2.763 · Cited by 985 · see citing works
Reconstruction of human evolution: bringing together genetic, archaeological, and linguistic data.
Cavalli-Sforza, L. L., Piazza, A., Menozzi, P., & Mountain, J. L. (1988) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.85.16.6002 · Cited by 910 · see citing works
Genotype, haplotype and copy-number variation in worldwide human populations
Jakobsson, M., Scholz, S. W., Scheet, P. A., Gibbs, J. R., Canzoniero, J. V., Fung, H., Szpiech, Z. A., Degnan, J. H., Wang, K., Guerreiro, R. J., et al. (2008) · Nature · doi:10.1038/nature06742 · Cited by 871 · see citing works
Genome-wide SNP and haplotype analyses reveal a rich history underlying dog domestication
vonHoldt, B. M., Pollinger, J. P., Lohmueller, K. E., Han, E., Parker, H. G., Quignon, P., Degenhardt, J. D., Boyko, A. R., Earl, D. A., Auton, A., et al. (2010) · Nature · doi:10.1038/nature08837 · Cited by 804 · see citing works
An aboriginal Australian genome reveals separate human dispersals into Asia
Rasmussen, M., Guo, X., Wang, Y., Lohmueller, K. E., Rasmussen, S., Albrechtsen, A., Skotte, L., Lindgreen, S., Metspalu, M., Jombart, T., et al. (2011) · Science · doi:10.1126/science.1211177 · Cited by 787 · see citing works
Using Environmental Correlations to Identify Loci Underlying Local Adaptation
Coop, G., Witonsky, D., Rienzo, A. D., & Pritchard, J. K. (2010) · Genetics · doi:10.1534/genetics.110.114819 · Cited by 701 · see citing works
Self-citationMaximum-likelihood estimation of evolutionary trees from continuous characters.
(1973) · Europe PMC (PubMed Central) · Cited by 700 · see citing works
Interpreting principal component analyses of spatial population genetic variation
Novembre, J., & Stephens, M. (2008) · Nature Genetics · doi:10.1038/ng.139 · Cited by 663 · see citing works
Denisova Admixture and the First Modern Human Dispersals into Southeast Asia and Oceania
Reich, D., Patterson, N., Kircher, M., Delfin, F., Nandineni, M. R., Pugach, I., Ko, A. M.-S., Ko, Y.-C., Jinam, T. A., Phipps, M. E., et al. (2011) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2011.09.005 · Cited by 656 · see citing works
Weir, B. S., & Hill, W. G. (2002) · Annual Review of Genetics · doi:10.1146/annurev.genet.36.050802.093940 · Cited by 650 · see citing works
Synthetic Maps of Human Gene Frequencies in Europeans
Menozzi, P., Piazza, A., & Cavalli-Sforza, L. L. (1978) · Science · doi:10.1126/science.356262 · Cited by 639 · see citing works
Calibrating a coalescent simulation of human genome sequence variation
Schaffner, S. F., Foo, C., Gabriel, S., Reich, D., Daly, M. J., & Altshuler, D. (2005) · Genome Research · doi:10.1101/gr.3709305 · Cited by 616 · see citing works
Bayesian inference of ancient human demography from individual genome sequences
Gronau, I., Hubisz, M. J., Gulko, B., Danko, C. G., & Siepel, A. C. (2011) · Nature Genetics · doi:10.1038/ng.937 · Cited by 580 · see citing works
A Genealogical Interpretation of Principal Components Analysis
McVean, G. (2009) · PLoS Genetics · doi:10.1371/journal.pgen.1000686 · Cited by 566 · see citing works
Huson, D. H., Rupp, R., & Scornavacca, C. (2010) · Cambridge University Press eBooks · doi:10.1017/cbo9780511974076 · Cited by 562 · see citing works
Sensitive detection of chromosomal segments of distinct ancestry in admixed populations
Price, A. L., Tandon, A., Patterson, N., Barnes, K. C., Rafaels, N., Ruczinski, I., Beaty, T. H., Mathias, R., Reich, D., & Myers, S. (2009) · PLoS Genetics · doi:10.1371/journal.pgen.1000519 · Cited by 539 · see citing works
A Simple Genetic Architecture Underlies Morphological Variation in Dogs
Boyko, A., Quignon, P., Li, L., Schoenebeck, J., Degenhardt, J. D., Lohmueller, K., Zhao, K., Brisbin, A., Parker, H., Vonholdt, B., et al. (2010) · PLoS Biology · doi:10.1371/journal.pbio.1000451 · Cited by 469 · see citing works
Felsenstein, J. (1981) · Evolution · doi:10.1111/j.1558-5646.1981.tb04991.x · Cited by 433 · see citing works
Genetic Structure of the Purebred Domestic Dog
Parker, H., Kim, L., Sutter, N., Carlson, S., Lorentzen, T. D., Malek, T. B., Johnson, G. S., DeFrance, H. B., Ostrander, E., & Kruglyak, L. (2004) · Science · doi:10.1126/science.1097406 · Cited by 405 · see citing works
Phylogenetic Networks: Concepts, Algorithms and Applications
Huson, D. H., Rupp, R., & Scornavacca, C. (2011) · Cited by 341 · see citing works
Genomic Ancestry of North Africans Supports Back-to-Africa Migrations
Henn, B. M., Botigué, L. R., Gravel, S., Wang, W., Brisbin, A., Byrnes, J. K., Fadhlaoui-Zid, K., Zalloua, P. A., Moreno-Estrada, A., Bertranpetit, J., et al. (2012) · PLoS Genetics · doi:10.1371/journal.pgen.1002397 · Cited by 331 · see citing works
Population Graphs: the graph theoretic shape of genetic structure
Dyer, R. J., & Nason, J. D. (2004) · Molecular Ecology · doi:10.1111/j.1365-294x.2004.02177.x · Cited by 315 · see citing works
Evolutionary relationships of human populations on a global scale.
Nei, M., & Roychoudhury, A. K. (1993) · Molecular Biology and Evolution · doi:10.1093/oxfordjournals.molbev.a040059 · Cited by 310 · see citing works
Detecting Selection in Population Trees: The Lewontin and Krakauer Test Extended
Bonhomme, M., Chevalet, C., Servin, B., Boitard, S., Abdallah, J., Blott, S. C., & SanCristobal, M. (2010) · Genetics · doi:10.1534/genetics.110.117275 · Cited by 280 · see citing works
Keinan, A., Mullikin, J. C., Patterson, N., & Reich, D. (2007) · Nature Genetics · doi:10.1038/ng2116 · Cited by 272 · see citing works
Nei, M., & Roychoudhury, A. K. (1974) · PubMed · Cited by 249 · see citing works
A new approach to estimate parameters of speciation models with application to apesPreprint
Becquet, C., & Przeworski, M. (2007) · Genome Research · doi:10.1101/gr.6409707 · Cited by 245 · see citing works
The History of African Gene Flow into Southern Europeans, Levantines, and Jews
Moorjani, P., Patterson, N. J., Hirschhorn, J. N., Keinan, A., Hao, L., Atzmon, G., Burns, E. R., D, H. O. M., Price, A. L., & Reich, D. (2011) · PLoS Genetics · doi:10.1371/journal.pgen.1001373 · Cited by 240 · see citing works
Assessing Population Differentiation and Isolation from Single-Nucleotide Polymorphism Data
Nicholson, G., Smith, A. V., Jónsson, F., Gústafsson, Ó., Stefánsson, K., & Donnelly, P. (2002) · Journal of the Royal Statistical Society Series B (Statistical Methodology) · doi:10.1111/1467-9868.00357 · Cited by 223 · see citing works
Demographic History of Oceania Inferred from Genome-wide Data
Wollstein, A., Lao, O., Becker, C., Brauer, S., Trent, R. J., Nürnberg, P., Stoneking, M., & Kayser, M. (2010) · Current Biology · doi:10.1016/j.cub.2010.10.040 · Cited by 218 · see citing works
Identifying Hybridization Events in the Presence of Coalescence via Model Selection
Kubatko, L. S. (2009) · Systematic Biology · doi:10.1093/sysbio/syp055 · Cited by 181 · see citing works
Analysis of Genomic Admixture in Uyghur and Its Implication in Mapping Strategy
Xu, S., Huang, W., Qian, J., & Li, J. (2008) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2008.01.017 · Cited by 178 · see citing works
Mitochondrial DNA and human evolution
Cann, R. L. (1996) · Oxford University Press eBooks · doi:10.1093/acprof:oso/9780198523901.003.0008 · Cited by 178 · see citing works
DeGiorgio, M., Jakobsson, M., & Rosenberg, N. A. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0903341106 · Cited by 175 · see citing works
Felsenstein, J. (1981) · Evolution · doi:10.2307/2408134 · Cited by 168 · see citing works
Analysis of evolution: Evolutionary rates, independence and treeness
Cavalli-Sforza, L. L., & Piazza, A. (1975) · Theoretical Population Biology · doi:10.1016/0040-5809(75)90029-5 · Cited by 157 · see citing works
Principal Component Analysis under Population Genetic Models of Range Expansion and Admixture
François, O., Currat, M., Ray, N., Han, E., Excoffier, L., & Novembre, J. (2010) · Molecular Biology and Evolution · doi:10.1093/molbev/msq010 · Cited by 149 · see citing works
How can we infer geography and history from gene frequencies?
Felsenstein, J. (1982) · Journal of Theoretical Biology · doi:10.1016/0022-5193(82)90152-7 · Cited by 148 · see citing works
Analytic review: some current problems of human population genetics.
Cavalli-Sforza, L. L. (1973) · PubMed · Cited by 111 · see citing works
Phylogenetic Networks: Concepts, Algorithms and Applications
Kelk, S. M. (2011) · Systematic Biology · doi:10.1093/sysbio/syr054 · Cited by 108 · see citing works
Bruette, W. A. (1921) · doi:10.5962/bhl.title.42425 · Cited by 101 · see citing works
Inferring Human Colonization History Using a Copying Model
Hellenthal, G., Auton, A., & Falush, D. (2008) · PLoS Genetics · doi:10.1371/journal.pgen.1000078 · Cited by 91 · see citing works
Perspectives on Human Population Structure at the Cusp of the Sequencing Era
Novembre, J., & Ramachandran, S. (2011) · Annual Review of Genomics and Human Genetics · doi:10.1146/annurev-genom-090810-183123 · Cited by 86 · see citing works
Bhatia, G., Patterson, N. J., Paşaniuc, B., Zaitlen, N., Genovese, G., Pollack, S. J., Mallick, S., Myers, S., Tandon, A., Spencer, C. C. A., et al. (2011) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2011.07.025 · Cited by 85 · see citing works
Nielsen, R., Mountain, J. L., Huelsenbeck, J. P., & Slatkin, M. (1998) · Evolution · doi:10.1111/j.1558-5646.1998.tb03692.x · Cited by 56 · see citing works
A Two-Stage Pruning Algorithm for Likelihood Computation for a Population Tree
RoyChoudhury, A., Felsenstein, J., & Thompson, E. A. (2008) · Genetics · doi:10.1534/genetics.107.085753 · Cited by 52 · see citing works
Evolutionary trees and admixture: phylogenetic inference when some populations are hybridized
Lathrop, M. G. (1982) · Annals of Human Genetics · doi:10.1111/j.1469-1809.1982.tb00716.x · Cited by 45 · see citing works
Reconstructing Population Histories from Single Nucleotide Polymorphism Data
Sirén, J., Marttinen, P., & Corander, J. (2010) · Molecular Biology and Evolution · doi:10.1093/molbev/msq236 · Cited by 43 · see citing works
Population genomics of domestic and wild yeastsPreprint
Carter, D. M., Liti, G., Moses, A. M., et al. (2008) · Nature Precedings · doi:10.1038/npre.2008.1988.1 · Cited by 33 · see citing works
Nielsen, R., Mountain, J. L., Huelsenbeck, J. P., et al. (1998) · Evolution · doi:10.2307/2411262 · Cited by 27 · see citing works
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Patterson, N., Moorjani, P., Luo, Y., Mallick, S., Rohland, N., Zhan, Y., Genschoreck, T., Webster, T., & Reich, D. (2012) · Genetics · doi:10.1534/genetics.112.145037 · Cited by 2,848 · see citing works
A high-coverage genome sequence from an archaic denisovan individual
Meyer, M., Kircher, M., Gansauge, M.-T., Li, H., Racimo, F., Mallick, S., Schraiber, J. G., Jay, F., Prüfer, K., de Filippo, C., et al. (2012) · Science · doi:10.1126/science.1224344 · Cited by 1,967 · see citing works
Massive migration from the steppe was a source for Indo-European languages in Europe
Haak, W., Lazaridis, I., Patterson, N., Rohland, N., Mallick, S., Llamas, B., Brandt, G., Nordenfelt, S., Harney, E., Stewardson, K., et al. (2015) · Nature · doi:10.1038/nature14317 · Cited by 1,940 · see citing works
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Raj, A., Stephens, M., & Pritchard, J. K. (2014) · Genetics · doi:10.1534/genetics.114.164350 · Cited by 1,666 · see citing works
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Lazaridis, I., Patterson, N., Mittnik, A., Renaud, G., Mallick, S., Kirsanow, K., Sudmant, P. H., Schraiber, J. G., Castellano, S., Lipson, M., et al. (2014) · Nature · doi:10.1038/nature13673 · Cited by 1,357 · see citing works
Dsuite ‐ Fast <i>D</i> ‐statistics and related admixture evidence from VCF files
Malinsky, M., Matschiner, M., & Svardal, H. (2021) · Molecular Ecology Resources · doi:10.1111/1755-0998.13265 · Cited by 992 · see citing works
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Raghavan, M., Skoglund, P., Graf, K. E., Metspalu, M., Albrechtsen, A., Moltke, I., Rasmussen, S., Stafford Jr, T. W., Orlando, L., Metspalu, E., et al. (2014) · Nature · doi:10.1038/nature12736 · Cited by 963 · see citing works
ipyrad: Interactive assembly and analysis of RADseq datasets
Eaton, D. A. R., & Overcast, I. (2019) · Bioinformatics · doi:10.1093/bioinformatics/btz966 · Cited by 883 · see citing works
Wild Mouse Gut Microbiota Promotes Host Fitness and Improves Disease Resistance
Rosshart, S. P., Vassallo, B. G., Angeletti, D., Hutchinson, D. S., Morgan, A. P., Takeda, K., Hickman, H. D., McCulloch, J. A., Badger, J. H., Ajami, N. J., et al. (2017) · Cell · doi:10.1016/j.cell.2017.09.016 · Cited by 862 · see citing works
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Hellenthal, G., Busby, G. B. J., Band, G., Wilson, J. F., Capelli, C., Falush, D., & Myers, S. (2014) · Science · doi:10.1126/science.1243518 · Cited by 798 · see citing works
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Freedman, A. H., Gronau, I., Schweizer, R. M., Ortega-Del Vecchyo, D., Han, E., Silva, P. M., Galaverni, M., Fan, Z., Marx, P., Lorente-Galdos, B., et al. (2014) · PLoS Genetics · doi:10.1371/journal.pgen.1004016 · Cited by 624 · see citing works
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Fu, Q., Meyer, M., Gao, X., Stenzel, U., Burbano, H. A., Kelso, J., & Pääbo, S. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1221359110 · Cited by 608 · see citing works
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Payseur, B. A., & Rieseberg, L. H. (2016) · Molecular Ecology · doi:10.1111/mec.13557 · Cited by 544 · see citing works
Genomic evidence for the Pleistocene and recent population history of Native Americans
Raghavan, M., Steinrücken, M., Harris, K., Schiffels, S., Rasmussen, S., DeGiorgio, M., Albrechtsen, A., Valdiosera, C., Ávila-Arcos, M. C., Malaspinas, A.-S., et al. (2015) · Science · doi:10.1126/science.aab3884 · Cited by 540 · see citing works
Inferring Phylogenetic Networks with Maximum Pseudolikelihood under Incomplete Lineage Sorting
Solís‐Lemus, C., & Ané, C. (2016) · PLoS Genetics · doi:10.1371/journal.pgen.1005896 · Cited by 526 · see citing works
Worldwide Patterns of Ancestry, Divergence, and Admixture in Domesticated Cattle
Decker, J. E., McKay, S. D., Rolf, M. M., Kim, J., Molina Alcalá, A., Sonstegard, T. S., Hanotte, O., Götherström, A., Seabury, C. M., Praharani, L., et al. (2014) · PLoS Genetics · doi:10.1371/journal.pgen.1004254 · Cited by 521 · see citing works
The prehistoric peopling of Southeast Asia
McColl, H., Racimo, F., Vinner, L., Demeter, F., Gakuhari, T., Moreno-Mayar, J. V., van Driem, G., Gram Wilken, U., Seguin-Orlando, A., de la Fuente Castro, C., et al. (2018) · Science · doi:10.1126/science.aat3628 · Cited by 517 · see citing works
Genome-Wide Scan for Adaptive Divergence and Association with Population-Specific Covariates
Gautier, M. (2015) · Genetics · doi:10.1534/genetics.115.181453 · Cited by 505 · see citing works
A population genetic signal of polygenic adaptation
Berg, J. J., & Coop, G. (2014) · PLoS Genetics · doi:10.1371/journal.pgen.1004412 · Cited by 487 · see citing works
The genetics of Mexico recapitulates Native American substructure and affects biomedical traits
Moreno-Estrada, A., Gignoux, C. R., Fernández-López, J. C., Zakharia, F., Sikora, M., Contreras, A. V., Acuña-Alonzo, V., Sandoval, K., Eng, C., Romero-Hidalgo, S., et al. (2014) · Science · doi:10.1126/science.1251688 · Cited by 478 · see citing works
Inferring admixture histories of human populations using linkage disequilibrium
Loh, P.-R., Lipson, M., Patterson, N., Moorjani, P., Pickrell, J. K., Reich, D., & Berger, B. (2013) · Genetics · doi:10.1534/genetics.112.147330 · Cited by 466 · see citing works
Self-citationAncient DNA indicates human population shifts and admixture in northern and southern China
Yang, M. A., Fan, X., Sun, B., Chen, C., Lang, J., Ko, Y., Tsang, C.-H., Chiu, H.-L., Wang, T., Bao, Q., et al. (2020) · Science · doi:10.1126/science.aba0909 · Cited by 465 · see citing works
PhyloNetworks: A Package for Phylogenetic Networks
Solís‐Lemus, C., Bastide, P., & Ané, C. (2017) · Molecular Biology and Evolution · doi:10.1093/molbev/msx235 · Cited by 457 · see citing works
Xia, E., Tong, W., Hou, Y., An, Y., Chen, L., Wu, Q., Liu, Y., Yu, J., Li, F., Li, R., et al. (2020) · Molecular Plant · doi:10.1016/j.molp.2020.04.010 · Cited by 457 · see citing works
Genomic and archaeological evidence suggest a dual origin of domestic dogs
Frantz, L., Mullin, V. E., Pionnier-Capitan, M., Lebrasseur, O., Ollivier, M., Perri, A. R., Linderholm, A. E., Mattiangeli, V., Teasdale, M. D., Dimopoulos, E. A., et al. (2016) · Science · doi:10.1126/science.aaf3161 · Cited by 449 · see citing works
Parker, H. G., Dreger, D. L., Rimbault, M., Davis, B. W., Mullen, A. B., Carpintero-Ramirez, G., & Ostrander, E. A. (2017) · Cell Reports · doi:10.1016/j.celrep.2017.03.079 · Cited by 438 · see citing works
Terminal Pleistocene Alaskan genome reveals first founding population of Native Americans
Moreno-Mayar, J. V., Potter, B. A., Vinner, L., Steinrücken, M., Rasmussen, S., Terhorst, J., Kamm, J., Albrechtsen, A., Malaspinas, A., Sikora, M., et al. (2018) · Nature · doi:10.1038/nature25173 · Cited by 423 · see citing works
Genomic insights into the peopling of the Southwest Pacific
Skoglund, P., Posth, C., Sirak, K., Spriggs, M., Valentin, F., Bedford, S., Clark, G. R., Reepmeyer, C., Petchey, F., Fernandes, D., et al. (2016) · Nature · doi:10.1038/nature19844 · Cited by 414 · see citing works
Natural selection interacts with recombination to shape the evolution of hybrid genomes
Schumer, M., Xu, C., Powell, D. L., Durvasula, A., Skov, L., Holland, C., Blazier, J. C., Sankararaman, S., Andolfatto, P., Rosenthal, G. G., et al. (2018) · Science · doi:10.1126/science.aar3684 · Cited by 412 · see citing works
Reconstructing Prehistoric African Population Structure
Skoglund, P., Thompson, J. C., Prendergast, M. E., Mittnik, A., Sirak, K. A., Hajdinjak, M., Salie, T., Rohland, N., Mallick, S., Peltzer, A., et al. (2017) · Cell · doi:10.1016/j.cell.2017.08.049 · Cited by 410 · see citing works
OptM : estimating the optimal number of migration edges on population trees using Treemix
Fitak, R. R. (2021) · Biology Methods and Protocols · doi:10.1093/biomethods/bpab017 · Cited by 404 · see citing works
Chen, N., Cai, Y., Chen, Q., Li, R., Wang, K., Huang, Y., Hu, S., Huang, S., Zhang, H., Zheng, Z., et al. (2018) · Nature Communications · doi:10.1038/s41467-018-04737-0 · Cited by 403 · see citing works
Characterization of Greater Middle Eastern genetic variation for enhanced disease gene discovery
Greater Middle East Variome Consortium, Scott, E. M., Halees, A., Itan, Y., Spencer, E. G., He, Y., Azab, M. A., Gabriel, S. B., Belkadi, A., Boisson, B., et al. (2016) · Nature Genetics · doi:10.1038/ng.3592 · Cited by 376 · see citing works
Ancient genomes revisit the ancestry of domestic and Przewalski’s horses
Gaunitz, C., Fages, A., Hanghøj, K., Albrechtsen, A., Khan, N., Schubert, M., Seguin‐Orlando, A., Owens, I. J., Felkel, S., Bignon‐Lau, O., et al. (2018) · Science · doi:10.1126/science.aao3297 · Cited by 371 · see citing works
Genomic Diversity and Admixture Differs for Stone-Age Scandinavian Foragers and Farmers
Skoglund, P., Malmström, H., Omrak, A., Raghavan, M., Valdiosera, C. E., Günther, T., Hall, P. N., Tambets, K., Parik, J., Sjögren, K.-G., et al. (2014) · Science · doi:10.1126/science.1253448 · Cited by 369 · see citing works
Early human dispersals within the Americas
Moreno-Mayar, J. V., Vinner, L., Damgaard, P. D. B., Castro, C. D. L. F., Chan, J., Spence, J. P., Allentoft, M. E., Vimala, T., Racimo, F., Pinotti, T., et al. (2018) · Science · doi:10.1126/science.aav2621 · Cited by 365 · see citing works
High-depth African genomes inform human migration and health
Choudhury, A., Aron, S., Botigué, L. R., Sengupta, D., Botha, G., Bensellak, T., Wells, G., Kumuthini, J., Shriner, D., Fakim, Y. J., et al. (2020) · Nature · doi:10.1038/s41586-020-2859-7 · Cited by 355 · see citing works
Wållberg, A., Fan, H., Wellhagen, G. J., Dahle, B., Kawata, M., Haddad, N. J., Simões, Z. L. P., Allsopp, M. H., Kandemi̇r, İ., la Rúa, P. D., et al. (2014) · Nature Genetics · doi:10.1038/ng.3077 · Cited by 354 · see citing works
Inferring Phylogenetic Networks Using PhyloNet
Wen, D., Yu, Y., Zhu, J., & Nakhleh, L. K. (2018) · Systematic Biology · doi:10.1093/sysbio/syy015 · Cited by 352 · see citing works
Out of southern East Asia: the natural history of domestic dogs across the world
Wang, G., Zhai, W., Yang, H., Wang, L., Li, Z., Yan-hu, L., Fan, R., Yin, T., Zhu, C., Poyarkov, A. D., et al. (2015) · Cell Research · doi:10.1038/cr.2015.147 · Cited by 350 · see citing works
Million-year-old DNA sheds light on the genomic history of mammoths
van der Valk, T., Pečnerová, P., Díez-del-Molino, D., Bergström, A., Oppenheimer, J., Hartmann, S., Xenikoudakis, G., Thomas, J. A., Dehasque, M., Sağlıcan, E., et al. (2021) · Nature · doi:10.1038/s41586-021-03224-9 · Cited by 345 · see citing works
Fariello, M. I., Boitard, S., Naya, H., SanCristobal, M., & Servin, B. (2013) · Genetics · doi:10.1534/genetics.112.147231 · Cited by 343 · see citing works
Frantz, L., Schraiber, J. G., Madsen, O., Megens, H., Cagan, A., Bosse, M., Paudel, Y., Crooijmans, R. P. M. A., Larson, G., & Groenen, M. A. M. (2015) · Nature Genetics · doi:10.1038/ng.3394 · Cited by 342 · see citing works
The genetic prehistory of southern Africa
Pickrell, J. K., Patterson, N. J., Barbieri, C., Berthold, F., Gerlach, L., Güldemann, T., Kure, B., Mpoloka, S. W., Nakagawa, H., Naumann, C., et al. (2012) · Nature Communications · doi:10.1038/ncomms2140 · Cited by 342 · see citing works
Self-citationYang, J. H., Li, W., Lv, F., He, S., Tian, S., Peng, W., Sun, Y., Zhao, Y., Tu, X.-L., Zhang, M., et al. (2016) · Molecular Biology and Evolution · doi:10.1093/molbev/msw129 · Cited by 342 · see citing works
Convergent genomic signatures of domestication in sheep and goats
Alberto, F. J., Boyer, F., Orozco-terWengel, P., Streeter, I., Servin, B., de Villemereuil, P., Benjelloun, B., Librado, P., Biscarini, F., Colli, L., et al. (2018) · Nature Communications · doi:10.1038/s41467-018-03206-y · Cited by 339 · see citing works
Adaptive introgression underlies polymorphic seasonal camouflage in snowshoe hares
Jones, M. R., Mills, L. S., Alves, P. C., Callahan, C. M., Alves, J. M., Lafferty, D. J. R., Jiggins, F. M., Jensen, J. D., Melo‐Ferreira, J., & Good, J. M. (2018) · Science · doi:10.1126/science.aar5273 · Cited by 331 · see citing works
A beginner's guide to low‐coverage whole genome sequencing for population genomics
Lou, R. N., Jacobs, A., Wilder, A. P., & Therkildsen, N. O. (2021) · Molecular Ecology · doi:10.1111/mec.16077 · Cited by 331 · see citing works
The genetic prehistory of the New World Arctic
Raghavan, M., DeGiorgio, M., Albrechtsen, A., Moltke, I., Skoglund, P., Korneliussen, T. S., Grønnow, B., Appelt, M., Gulløv, H. C., Friesen, T. M., et al. (2014) · Science · doi:10.1126/science.1255832 · Cited by 329 · see citing works
Tracking Five Millennia of Horse Management with Extensive Ancient Genome Time Series
Fages, A., Hanghøj, K., Khan, N., Gaunitz, C., Seguin‐Orlando, A., Leonardi, M., Constantz, C. M., Gamba, C., Al‐Rasheid, K. A. S., Albizuri, S., et al. (2019) · Cell · doi:10.1016/j.cell.2019.03.049 · Cited by 328 · see citing works
Stable recombination hotspots in birds
Singhal, S., Leffler, E. M., Sannareddy, K., Turner, I., Venn, O., Hooper, D. M., Strand, A. I., Li, Q., Raney, B. J., Balakrishnan, C. N., et al. (2015) · Science · doi:10.1126/science.aad0843 · Cited by 327 · see citing works
Prehistoric genomes reveal the genetic foundation and cost of horse domestication
Schubert, M., Jónsson, H., Chang, D., Der Sarkissian, C., Ermini, L., Ginolhac, A., Albrechtsen, A., Dupanloup, I., Foucal, A., Petersen, B., et al. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1416991111 · Cited by 324 · see citing works
Genomic structure in Europeans dating back at least 36,200 years
Seguin-Orlando, A., Korneliussen, T. S., Sikora, M., Malaspinas, A.-S., Manica, A., Moltke, I., Albrechtsen, A., Ko, A., Margaryan, A., Moiseyev, V., et al. (2014) · Science · doi:10.1126/science.aaa0114 · Cited by 315 · see citing works
Ming, L., Yuan, L., Yi, L., Ding, G., Hasi, S., Chen, G., Jambl, T., Hedayat-Evright, N., Batmunkh, M., Бадмаевна, Г. Х., et al. (2020) · Communications Biology · doi:10.1038/s42003-019-0734-6 · Cited by 315 · see citing works
Shen, C., Du, H., Chen, Z., Lu, H., Zhu, F., Chen, H., Meng, X., Liu, Q., Liu, P., Zheng, L., et al. (2020) · Molecular Plant · doi:10.1016/j.molp.2020.07.003 · Cited by 308 · see citing works
Inferring Continuous and Discrete Population Genetic Structure Across Space
Bradburd, G. S., Coop, G., & Ralph, P. L. (2018) · Genetics · doi:10.1534/genetics.118.301333 · Cited by 306 · see citing works
Chimpanzee genomic diversity reveals ancient admixture with bonobos
de Manuel, M., Kuhlwilm, M., Frandsen, P., Sousa, V. C., Desai, T., Prado-Martinez, J., Hernández-Rodríguez, J., Dupanloup, I., Lao, Ó., Hallast, P., et al. (2016) · Science · doi:10.1126/science.aag2602 · Cited by 297 · see citing works
Reconstructing Austronesian population history in Island Southeast Asia
Lipson, M., Loh, P., Patterson, N. J., Moorjani, P., Ko, Y., Stoneking, M., Berger, B., & Reich, D. (2014) · Nature Communications · doi:10.1038/ncomms5689 · Cited by 296 · see citing works
Animal domestication in the era of ancient genomics
Frantz, L., Bradley, D. G., Larson, G., & Orlando, L. (2020) · Nature Reviews Genetics · doi:10.1038/s41576-020-0225-0 · Cited by 290 · see citing works
Dual domestications and origin of traits in grapevine evolution
Dong, Y., Duan, S., Xia, Q., Liang, Z., Xiao, D., Margaryan, K., Musayev, M., Goryslavets, S., Zdunić, G., Bert, P., et al. (2023) · Science · doi:10.1126/science.add8655 · Cited by 290 · see citing works
The genetics of monarch butterfly migration and warning colouration
Zhan, S., Zhang, W., Niitepõld, K., Hsu, J. L., Haeger, J. F., Zalucki, M. P., Altizer, S., de Roode, J. C., Reppert, S. M., & Kronforst, M. R. (2014) · Nature · doi:10.1038/nature13812 · Cited by 288 · see citing works
Admixture into and within sub-Saharan Africa
Busby, G., Band, G., Le, S. Q., Jallow, M., Bougama, E., Mangano, V. D., Amenga-Etego, L. N.-K., Enimil, A. K., Apinjoh, T. O., Ndila, C., et al. (2016) · eLife · doi:10.7554/elife.15266 · Cited by 288 · see citing works
Genome-culture coevolution promotes rapid divergence of killer whale ecotypes
Foote, A. D., Vijay, N., Ávila‐Arcos, M. C., Baird, R. W., Durban, J. W., Fumagalli, M., Gibbs, R. A., Hanson, M. B., Korneliussen, T. S., Martin, M. D., et al. (2016) · Nature Communications · doi:10.1038/ncomms11693 · Cited by 288 · see citing works
863 genomes reveal the origin and domestication of chicken
Wang, M.-S., Thakur, M., Peng, M.-S., Jiang, Y., Frantz, L. A. F., Li, M., Zhang, J.-J., Wang, S., Peters, J., Otecko, N. O., et al. (2020) · Cell Research · doi:10.1038/s41422-020-0349-y · Cited by 286 · see citing works
Understanding the origin of species with genome-scale data: modelling gene flow
Sousa, V. C., & Hey, J. (2013) · Nature Reviews Genetics · doi:10.1038/nrg3446 · Cited by 284 · see citing works
Ancient genomes link early farmers from Atapuerca in Spain to modern-day Basques
Günther, T., Valdiosera, C., Malmström, H., Ureña, I., Rodriguez-Varela, R., Sverrisdóttir, Ó. O., Daskalaki, E. A., Skoglund, P., Naidoo, T., Svensson, E. M., et al. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1509851112 · Cited by 278 · see citing works
On the limits of fitting complex models of population history to f-statistics
Maier, R., Flegontov, P., Flegontova, O., Işıldak, U., Changmai, P., & Reich, D. (2023) · eLife · doi:10.7554/elife.85492 · Cited by 274 · see citing works
The Genome Landscape of Indigenous African Cattle
Kim, J., Hanotte, O., Mwai, O. A., Dessie, T., Bashir, S., Diallo, B., Agaba, M., Kim, K., Kwak, W., Sung, S., et al. (2017) · Genome biology · doi:10.1186/s13059-017-1153-y · Cited by 271 · see citing works
Toward a new history and geography of human genes informed by ancient DNA
Pickrell, J. K., & Reich, D. (2014) · Trends in Genetics · doi:10.1016/j.tig.2014.07.007 · Cited by 271 · see citing works
Self-citationWu, D., Liang, Z., Yan, T., Xu, Y. C., Xuan, L., Tang, J., Zhou, G., Lohwasser, U., Hua, S., Wang, H., et al. (2018) · Molecular Plant · doi:10.1016/j.molp.2018.11.007 · Cited by 262 · see citing works
The future of ancient DNA: Technical advances and conceptual shifts
Hofreiter, M., Paijmans, J. L. A., Goodchild, H., Speller, C., Barlow, A., Fortes, G. G., Thomas, J. A., Ludwig, A., & Collins, M. J. (2014) · BioEssays · doi:10.1002/bies.201400160 · Cited by 260 · see citing works
Speciation and introgression between Mimulus nasutus and Mimulus guttatus
Brandvain, Y., Kenney, A. M., Flagel, L., Coop, G., & Sweigart, A. L. (2014) · PLoS Genetics · doi:10.1371/journal.pgen.1004410 · Cited by 259 · see citing works
Schoville, S. D., Chen, Y. H., Andersson, M. N., Benoit, J. B., Bhandari, A., Bowsher, J. H., Brevik, K. A., Cappelle, K., Chen, M.-J. M., Childers, A. K., et al. (2018) · Scientific Reports · doi:10.1038/s41598-018-20154-1 · Cited by 258 · see citing works
Admixture, Population Structure, and F -Statistics
Peter, B. M. (2016) · Genetics · doi:10.1534/genetics.115.183913 · Cited by 256 · see citing works
Recent History of Aedes aegypti : Vector Genomics and Epidemiology Records
Powell, J. R., Gloria‐Soria, A., & Kotsakiozi, P. (2018) · BioScience · doi:10.1093/biosci/biy119 · Cited by 255 · see citing works
Ancient Genomics of Modern Humans: The First Decade
Skoglund, P., & Mathieson, I. (2018) · Annual Review of Genomics and Human Genetics · doi:10.1146/annurev-genom-083117-021749 · Cited by 246 · see citing works
A graph-based genome and pan-genome variation of the model plant Setaria
He, Q., Tang, S., Zhi, H., Chen, J., Zhang, J., Liang, H., Alam, O., Li, H., Zhang, H., Xing, L., et al. (2023) · Nature Genetics · doi:10.1038/s41588-023-01423-w · Cited by 244 · see citing works
Admixture facilitates genetic adaptations to high altitude in Tibet
Jeong, C., Alkorta‐Aranburu, G., Basnyat, B., Neupane, M., Witonsky, D., Pritchard, J. K., Beall, C. M., & Rienzo, A. D. (2014) · Nature Communications · doi:10.1038/ncomms4281 · Cited by 237 · see citing works
Self-citation40,000-Year-Old Individual from Asia Provides Insight into Early Population Structure in Eurasia
Yang, M. A., Gao, X., Theunert, C., Tong, H., Aximu‐Petri, A., Nickel, B., Slatkin, M., Meyer, M., Pääbo, S., Kelso, J. F., et al. (2017) · Current Biology · doi:10.1016/j.cub.2017.09.030 · Cited by 237 · see citing works
Species boundaries in the human pathogen Paracoccidioides
Turissini, D. A., Gómez, O. M., Teixeira, M. D. M., McEwen, J. G., & Matute, D. R. (2017) · Fungal Genetics and Biology · doi:10.1016/j.fgb.2017.05.007 · Cited by 236 · see citing works
The deep population history of northern East Asia from the Late Pleistocene to the Holocene
Mao, X., Zhang, H., Qiao, S., Liu, Y., Chang, F., Xie, P., Zhang, M., Wang, T., Li, M., Cao, P., et al. (2021) · Cell · doi:10.1016/j.cell.2021.04.040 · Cited by 234 · see citing works
Pervasive introgression facilitated domestication and adaptation in the Bos species complex
Wu, D., Ding, X., Wang, S., Wójcik, J. M., Zhang, Y., Tokarska, M., Li, Y., Wang, M.-S., Faruque, O., Nielsen, R., et al. (2018) · Nature Ecology & Evolution · doi:10.1038/s41559-018-0562-y · Cited by 233 · see citing works
Genetic structure in village dogs reveals a Central Asian domestication origin
Shannon, L. M., Boyko, R. H., Castelhano, M. G., Corey, E. E., Hayward, J. J., McLean, C., White, M. E., Said, M. A., Anita, B. A., Ikombe, N. B., et al. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1516215112 · Cited by 229 · see citing works
Park, S. D. E., Magee, D. A., McGettigan, P., Teasdale, M. D., Edwards, C. J., Lohan, A. J., Murphy, A., Braud, M., Donoghue, M. T. A., Liu, Y., et al. (2015) · Genome biology · doi:10.1186/s13059-015-0790-2 · Cited by 228 · see citing works
Genomic Evidence for Complex Domestication History of the Cultivated Tomato in Latin America
Razifard, H., Ramos, A., Valle, A. L. D., Bodary, C., Goetz, E., Manser, E. J., Li, X., Zhang, L., Visa, S., Tieman, D. M., et al. (2019) · Molecular Biology and Evolution · doi:10.1093/molbev/msz297 · Cited by 223 · see citing works
Ancient goat genomes reveal mosaic domestication in the Fertile Crescent
Daly, K. G., Delser, P. M., Mullin, V. E., Scheu, A., Mattiangeli, V., Teasdale, M. D., Hare, A. J., Bürger, J., Verdugo, M. P., Collins, M. J., et al. (2018) · Science · doi:10.1126/science.aas9411 · Cited by 223 · see citing works
Genomic Analyses Reveal Potential Independent Adaptation to High Altitude in Tibetan Chickens
Wang, M., Li, Y., Peng, M., Zhong, L., Wang, Z., Li, Q., Tu, X.-L., Dong, Y., Zhu, C., Wang, L., et al. (2015) · Molecular Biology and Evolution · doi:10.1093/molbev/msv071 · Cited by 222 · see citing works
Ancient genomic changes associated with domestication of the horse
Librado, P., Gamba, C., Gaunitz, C., Sarkissian, C. S. I. D., Pruvost, M., Albrechtsen, A., Fages, A., Khan, N., Schubert, M., Jagannathan, V., et al. (2017) · Science · doi:10.1126/science.aam5298 · Cited by 222 · see citing works
Genomic landscape of human diversity across Madagascar
Pierron, D., Heiske, M., Razafindrazaka, H., Rakoto, I., Rabetokotany, N., Ravololomanga, B., Rakotozafy, L., Rakotomalala, M., Razafiarivony, M., Rasoarifetra, B., et al. (2017) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1704906114 · Cited by 222 · see citing works
High-dimensional asymptotics of prediction: Ridge regression and classification
Dobriban, E., & Wager, S. (2018) · The Annals of Statistics · doi:10.1214/17-aos1549 · Cited by 220 · see citing works
Speciation with gene flow in equids despite extensive chromosomal plasticity
Jónsson, H., Schubert, M., Seguin‐Orlando, A., Ginolhac, A., Petersen, L., Fumagalli, M., Albrechtsen, A., Petersen, B., Korneliussen, T. S., Vilstrup, J. T., et al. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1412627111 · Cited by 219 · see citing works
Genetic Signatures Reveal High-Altitude Adaptation in a Set of Ethiopian Populations
Huerta‐Sánchez, E., DeGiorgio, M., Pagani, L., Tarekegn, A., Ekong, R., Antão, T., Cardona, A., Montgomery, H., Cavalleri, G. L., Robbins, P. A., et al. (2013) · Molecular Biology and Evolution · doi:10.1093/molbev/mst089 · Cited by 217 · see citing works
Genome-wide data substantiate Holocene gene flow from India to Australia
Pugach, I., Delfin, F. C., Gunnarsdóttir, E. D., Kayser, M., & Stoneking, M. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1211927110 · Cited by 216 · see citing works
Assessing the performance of qpAdm: a statistical tool for studying population admixture
Harney, É., Patterson, N. J., Reich, D., & Wakeley, J. (2021) · Genetics · doi:10.1093/genetics/iyaa045 · Cited by 216 · see citing works
Eaton, D. A. R., Hipp, A. L., González‐Rodríguez, A., & Cavender-Bares, J. M. (2015) · Evolution · doi:10.1111/evo.12758 · Cited by 212 · see citing works
- Authors
- Pickrell, J. K., & Pritchard, J. K.
- Affiliations
- University of Chicago (US)
- Howard Hughes Medical Institute (US)
- Corresponding author
- Pickrell, Joseph K.
- Pritchard, Jonathan K.
- Venue
- PLoS Genetics
- Publisher
- Public Library of Science (PLoS)
- Published
- 2012-11-15
- Volume
- 8
- Issue
- 11
- Pages
- e1002967
- ISSN
- 1553-7390 (ISSN-L)
- 1553-7404
- PMC
- PMC3499260
- OpenAlex
- W2093044565
- Cited by
- 2,731
- References
- 79
- Citations by year
- 2026: 223 · 2025: 260 · 2024: 362 · 2023: 271 · 2022: 277 · 2021: 346 · 2020: 222 · 2019: 175 · 2018: 180 · 2017: 117 · 2016: 120 · 2015: 80 · 2014: 65 · 2013: 22 · 2012: 7
- FWCI
- 33.43
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- PLoS Genetics (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- arXiv (Cornell University) (submittedVersion)
- Figshare (submittedVersion, cc-by)
- Knowledge@UChicago (University of Chicago) (submittedVersion, cc-by-nc-nd)
- RePEc: Research Papers in Economics (submittedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Nature Precedings (submittedVersion)
- arXiv (Cornell University)
- University of Chicago (cc-by)
- Funders
- Howard Hughes Medical Institute
- National Institutes of Health
- National Institute of Mental Health (R01MH084703, MH084703)
- National Institute of General Medical Sciences (F32GM103098)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Forensic and Genetic Research
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic diversity and population structure
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic Associations and Epidemiology
- Keywords
- population admixture, population structure inference, migration events, dog breeds, wild canids, genetic drift, TreeMix, dog domestication, Shih Tzu, Pekingese
- MeSH terms
- Algorithms, Animals, Breeding, Dogs, Gene Frequency, Humans, Models, Genetic, Population, Wolves, Polymorphism, Single Nucleotide, Genetic Drift, Genome-Wide Association Study
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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