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The DOI matches its Crossref record; 57 of the 57 references it cites were found in a registry or an index.

Effects of a Physical Activity Intervention on Measures of Physical Performance: Results of the Lifestyle Interventions and Independence for Elders Pilot (LIFE-P) Study

The LIFE Study Investigators* [*See Appendix for List of LIFE Study Investigators·2006·The Journals of Gerontology Series A: Biological Sciences and Medical Sciences

Abstract

BACKGROUND: The Short Physical Performance Battery (SPPB), which includes walking, balance, and chair stands tests, independently predicts mobility disability and activities of daily living disability. To date, however, there is no definitive evidence from randomized controlled trials that SPPB scores can be improved. Our objective was to assess the effect of a comprehensive physical activity (PA) intervention on the SPPB and other physical performance measures. METHODS: A total of 424 sedentary persons at risk for disability (ages 70-89 years) were randomized to a moderate-intensity PA intervention or a successful aging (SA) health education intervention and were followed for an average of 1.2 years. RESULTS: The mean baseline SPPB score on a scale of 0-12, with 12 corresponding to highest performance, was 7.5. At 6 and 12 months, the PA versus SA group adjusted SPPB (+/- standard error) scores were 8.7 +/- 0.1 versus 8.0 +/- 0.1, and 8.5 +/- 0.1 versus 7.9 +/- 0.2, respectively (p < .001). The 400-meter walking speed was also significantly improved in the PA group. The PA group had a lower incidence of major mobility disability defined as incapacity to complete a 400-meter walk (hazard ratio = 0.71, 95% confidence interval = 0.44-1.20). CONCLUSIONS: A structured PA intervention improved the SPPB score and other measures of physical performance. An intervention that improves the SPPB performance may also offer benefit on more distal health outcomes, such as mobility disability.

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Show all 57 references

Research works printed but not linked: 28

  1. 2004, The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 59A, 255
  2. 2004, The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 59A, 1056
  3. 2005, The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 60A, 894
  4. 2005, The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 60A, 74
  5. 2000, The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 55A, M221
  6. 2000, The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 55A, M691
  7. 2004, The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 59A, 242
  8. 2003, The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 58A, 171
  9. 1999, The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 54A, M242
  10. Buchner, 1997, Aging (Milan, Italy), 9, 112
  11. Ettinger, 1997, JAMA, 277, 25, 10.1001/jama.1997.03540250033028 · DOI · Paper page
  12. 2006, The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 61A, 184
  13. 2005, The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 60A, 777
  14. 2004, The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 59A, 1200
  15. 2003, The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 58A, 740
  16. 2004, The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 59A, 154
  17. 2001, The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 56A, M465
  18. 2005, The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 60A, 1304
  19. 2002, The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 57A, M347
  20. 2006, The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 61A, 97
  21. 2005, The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 60A, 768
  22. 2005, The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 60A, 1425
  23. 2005, The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 60A, 307
  24. 2003, The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 58A, M846
  25. 2004, The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 59A, 1062
  26. 2006, The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 61A, 78
  27. 2004, The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 59A, 503
  28. 2001, The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 56A, M412

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Metadata

Authors
The LIFE Study Investigators* [*See Appendix for List of LIFE Study Investigators
Venue
The Journals of Gerontology Series A: Biological Sciences and Medical Sciences
Published
2006-11-01
Volume
61
Issue
11
Pages
1157-1165
ISSN
  • 1079-5006 (ISSN-L)
  • 1758-535X
OpenAlex
W1585264374
Cited by
663
References
57
FWCI
13.52
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Effects of a Physical Activity Intervention on Measures of Physical Performance: Results of the Lifestyle Interventions and Independence for Elders Pilot (LIFE-P) Study. https://app.cochat.ai/papers/10.1093/gerona/61.11.1157
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The LIFE Study Investigators* [*See Appendix for List of LIFE Study Investigators. (2006). Effects of a Physical Activity Intervention on Measures of Physical Performance: Results of the Lifestyle Interventions and Independence for Elders Pilot (LIFE-P) Study. The Journals of Gerontology Series A: Biological Sciences and Medical Sciences. https://doi.org/10.1093/gerona/61.11.1157

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