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Polypharmacy Among Adults Aged 65 Years and Older in the United States: 1988–2010
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BACKGROUND: Older adults frequently have several chronic health conditions which require multiple medications. We illustrated trends in prescription medication use over 20 years in the United States, and described characteristics of older adults using multiple medications in 2009-2010. METHODS: Participants included 13,869 adults aged 65 years and older in the National Health & Nutrition Examination Survey (1988-2010). Prescription medication use was verified by medication containers. Potentially inappropriate medications were defined by the 2003 Beers Criteria. RESULTS: Between 1988 and 2010 the median number of prescription medications used among adults aged 65 and older doubled from 2 to 4, and the proportion taking ≥5 medications tripled from 12.8% (95% confidence interval: 11.1, 14.8) to 39.0% (35.8, 42.3).These increases were driven, in part, by rising use of cardioprotective and antidepressant medications. Use of potentially inappropriate medications decreased from 28.2% (25.5, 31.0) to 15.1% (13.2, 17.3) between 1988 and 2010. Higher medication use was associated with higher prevalence of functional limitation, activities of daily living limitation, and confusion/memory problems in 2009-2010, although these associations did not remain after adjustment for covariates. In multivariable models, older age, number of chronic conditions, and annual health care visits were associated with increased odds of using both 1-4 and ≥5 medications. Additionally, body mass index, higher income-poverty ratio, former smoking, and non-black non-white race were associated with use of ≥5 medications. CONCLUSIONS: Prescription medication use increased dramatically among older adults between 1988 and 2010. Contemporary older adults on multiple medications have worse health status compared with those on less medications, and appear to be a vulnerable population.
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“and this number had tripled from that 20 years ago [3]”
From Benefits of, Barriers to, and Needs for an Artificial Intelligence–Powered Medication Information Voice Chatbot for Older Adults: Interview Study With Geriatrics Experts (2022) · cites this paper as [3]
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“One study estimated that 39% of older adults had ≥5 concurrent prescriptions”
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Stone, N. J., Robinson, J. G., Lichtenstein, A. H., Bairey Merz, C. N., Blum, C. B., Eckel, R. H., Goldberg, A. C., Gordon, D., Levy, D., Lloyd-Jones, D. M., et al. (2014) · Circulation · doi:10.1161/01.cir.0000437738.63853.7a · Cited by 7,081
Fick, D. M., Cooper, J. W., Wade, W. E., Waller, J. L., Maclean, J. R., & Beers, M. H. (2003) · Archives of Internal Medicine · doi:10.1001/archinte.163.22.2716 · Cited by 2,389
US trends in prevalence, awareness, treatment, and control of hypertension, 1988–2008
Egan, B. M. (2010) · JAMA · doi:10.1001/jama.2010.650 · Cited by 2,197
Clinical consequences of polypharmacy in elderly
Maher, R. L., Hanlon, J. T., & Hajjar, E. R. (2013) · Expert Opinion on Drug Safety · doi:10.1517/14740338.2013.827660 · Cited by 1,970
Kaufman, D. W., Kelly, J. P., Rosenberg, L., Anderson, T. E., & Mitchell, A. A. (2002) · JAMA · doi:10.1001/jama.287.3.337 · Cited by 1,845
National health and nutrition examination survey: analytic guidelines, 1999-2010.
Cl, J., Paulose‐Ram, R., Ogden, C. L., Carroll, Kruszon‐Moran, D., Dohrmann, S. M., & Curtin, L. R. (2013) · PubMed · Cited by 1,522
Polypharmacy in elderly patients
Hajjar, E. R., Cafiero, A. C., & Hanlon, J. T. (2007) · The American Journal of Geriatric Pharmacotherapy · doi:10.1016/j.amjopharm.2007.12.002 · Cited by 1,275
Smith, S. C., Jr. (2019) · Carolina Digital Repository (University of North Carolina at Chapel Hill) · doi:10.17615/ahxt-ag78 · Cited by 1,037
Anderson, I. M. (2000) · Journal of Affective Disorders · doi:10.1016/s0165-0327(99)00092-0 · Cited by 940
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Research works printed but not linked: 4
- CDC, Patterns of Prescription Drug Use in the United States, 1988–94
- Johnson, 2013, NHANES: Analytic Guidelines, 1999–2010, Vital & Health Statistics, 2
- AMDA, Choosing Wisely: Five Things Physicians and Patients Should Question
- 10.1176/appi.ps.58.5.642 · DOI · Paper page
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Items 201–300 of 569
Katsukunya, J. N., Soko, N. D., Naidoo, J., Rayner, B. L., Blom, D. J., Sinxadi, P., Chimusa, E. R., Dandara, M. T. L., Dzobo, K., Jones, E. S. W., et al. (2023) · International Journal of Hypertension · doi:10.1155/2023/9919677 · Cited by 13
Li, Q., Shang, N., Gao, Q., Guo, S., & Yang, T. (2025) · BMC Geriatrics · doi:10.1186/s12877-025-06060-y · Cited by 13
Tesfaye, W. H., Wimmer, B. C., Peterson, G. M., Castelino, R. L., Jose, M., McKercher, C., & Zaidi, S. T. R. (2018) · Current Medical Research and Opinion · doi:10.1080/03007995.2018.1560193 · Cited by 13
Pharmacoepidemiology in older people: Purposes and future directions
Laroche, M., Sirois, C., Reeve, E., Gnjidic, D., & Morin, L. (2019) · Therapies · doi:10.1016/j.therap.2018.10.006 · Cited by 13
Usmani, S. A., Reckenberg, K., Johnson, O., Stranges, P. M., Teshome, B. F., Kebodeaux, C. D., & Vouri, S. M. (2019) · Drugs & Aging · doi:10.1007/s40266-019-00674-9 · Cited by 13
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Alshehri, S. O., Alshibani, M., Magboul, G., Albandar, A. A., Nasser, R., Yaqoub, R., Alzuhayri, J., & Aljabri, A. M. (2020) · Geriatrics · doi:10.3390/geriatrics5040097 · Cited by 13
Prats, C. H., López-Pintor, E., & Lumbreras, B. (2021) · Research in Social and Administrative Pharmacy · doi:10.1016/j.sapharm.2021.06.023 · Cited by 13
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Kwakye, A. O., Kretchy, I. A., & Oppong, K. G. (2023) · Scientific African · doi:10.1016/j.sciaf.2023.e02028 · Cited by 14
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Soon, H. C., Geppetti, P., Lupi, C., & Kho, B. P. (2020) · Springer eBooks · doi:10.1007/978-3-030-59403-9_31 · Cited by 12
Yu, J., Cao, H., Li, X., Chang, Y., Li, Y., & Guo, H. (2023) · BMC Musculoskeletal Disorders · doi:10.1186/s12891-023-06166-7 · Cited by 12
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Furlan, G., Caduff‐Janosa, P., Sottosanti, L., Cappello, E., Valdiserra, G., & Tuccori, M. (2020) · Drug Safety · doi:10.1007/s40264-020-00949-w · Cited by 14
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Marques, L., & Vale, N. (2025) · Pharmaceutics · doi:10.3390/pharmaceutics17060747 · Cited by 12
Chinthalapudi, S. S., Cheeti, S., Bajpai, A., Deepika, S., Thunga, G., Rashid, M., Acharya, R. V., & Nair, S. (2021) · Current Drug Safety · doi:10.2174/1574886316666210423113916 · Cited by 11
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Killam-Worrall, L., Brand, R., Castro, J. R., Patel, D. S., Huynh, K., Lindley, B., & Palasik, B. N. (2023) · Annals of Pharmacotherapy · doi:10.1177/10600280231193080 · Cited by 11
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Mattos, M. K., Sereika, S. M., Naples, J. G., & Albert, S. M. (2016) · Drugs - Real World Outcomes · doi:10.1007/s40801-016-0080-7 · Cited by 11
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Wastesson, J. W., Fastbom, J., & Johnell, K. (2016) · Journal of the American Medical Directors Association · doi:10.1016/j.jamda.2016.07.006 · Cited by 11
Simões, P. A., Santiago, L. M., & Simões, J. A. (2020) · Archives of Medical Science · doi:10.5114/aoms.2020.93537 · Cited by 11
Gualtieri, L. N., Shaveet, E., Estime, B., & Patel, A. (2022) · Frontiers in Digital Health · doi:10.3389/fdgth.2022.999981 · Cited by 16
Kardas, P., Mair, A. R., Stewart, D. C., & Lewek, P. (2023) · Frontiers in Pharmacology · doi:10.3389/fphar.2023.1254912 · Cited by 11
Baptista, L. C. P., Jaeger, B. C., Anton, S. D., Bavry, A. A., Handberg, E. M., Gardner, A. K., Harper, S. A., Roberts, L. M., Sandesara, B. D., Carter, C. S., et al. (2019) · Journal of Clinical Medicine · doi:10.3390/jcm8020196 · Cited by 11
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Buda, V. O., Prelipcean, A., Cristescu, C., Roja, A., Dalleur, O., Andor, M., Danciu, C., Ledeţi, A., Dehelean, C. A., & Cretu, O. M. (2021) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph18137043 · Cited by 11
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Nakao, S., Hasegawa, S., Shimada, K., Mukai, R., Tanaka, M., Matsumoto, K., Uranishi, H., Masuta, M., Ikesue, H., Hashida, T., et al. (2020) · International Journal of Medical Sciences · doi:10.7150/ijms.43789 · Cited by 11
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Sluggett, J. K., Page, A. T., Chen, E. Y. H., Ilomäki, J., Corlis, M. E., Emden, J. V., Hogan, M., Caporale, T., Angley, M. T., Hilmer, S. N., et al. (2019) · BMJ Open · doi:10.1136/bmjopen-2018-025345 · Cited by 10
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Zong, Q., Feng, Z., Wang, J., Zheng, Z., Chen, C., & Feng, D. (2023) · BMC Geriatrics · doi:10.1186/s12877-023-03968-1 · Cited by 7
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Mion, L. C., & Sandhu, S. K. (2016) · Geriatric Nursing · doi:10.1016/j.gerinurse.2016.02.006 · Cited by 7
Ie, K., Chou, E., Boyce, R. D., & Albert, S. M. (2017) · Drugs - Real World Outcomes · doi:10.1007/s40801-017-0123-8 · Cited by 7
Drumond, N., & Stegemann, S. (2019) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2019.02.012 · Cited by 7
Vidoni, E. D., Kamat, A., Gahan, W. P., Ourso, V., Woodard, K. T., Kerwin, D. R., Binder, E. F., Burns, J. M., Cullum, C. M., Hynan, L. S., et al. (2020) · Journal of Alzheimer s Disease · doi:10.3233/jad-200122 · Cited by 7
Mekonnen, G. B., & Beyna, A. T. (2020) · BioMed Research International · doi:10.1155/2020/7695692 · Cited by 7
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Rosli, N., & Teo, S. P. (2021) · Asian Journal of Gerontology and Geriatrics · doi:10.12809/ajgg-2020-411-ra · Cited by 7
Hazzouri, A. Z. A., Jawadekar, N., Grasset, L., Kaiser, P., Kezios, K., Calónico, S., Glymour, M. M., Hirsch, C. H., Arnold, A. M., Varadhan, R., et al. (2021) · The Journals of Gerontology Series A · doi:10.1093/gerona/glab220 · Cited by 7
Self-citationLam, K., Price, E. L., Garg, M., Baskin, N., Dunchak, M., Hooper, S., Fabiny, A., & Eng, J. A. (2021) · NEJM Catalyst · doi:10.1056/cat.21.0204 · Cited by 7
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Polypharmacy: A Five-Step Call to Action for Family Physicians
Tarn, D. M., & Schwartz, J. B. (2020) · Family Medicine · doi:10.22454/fammed.2020.909136 · Cited by 6
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Pepito, B. M. L., & Ross, C. F. (2024) · Journal of Food Science · doi:10.1111/1750-3841.17127 · Cited by 6
Khan, N., Chattopadhyay, K., & Leonardi‐Bee, J. (2019) · The JBI Database of Systematic Reviews and Implementation Reports · doi:10.11124/jbisrir-d-18-00001 · Cited by 6
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Boér, K., Rubovszky, G., Rokszin, G., Abonyi‐Tóth, Z., Földesi, C., & Dank, M. (2021) · OncoTargets and Therapy · doi:10.2147/ott.s309862 · Cited by 6
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Coe, A. B., Farris, K. B., Solway, E. S., Singer, D., Kirch, M., Kullgren, J. T., Malani, P., & Bynum, J. (2022) · The Journals of Gerontology Series A · doi:10.1093/gerona/glac096 · Cited by 6
Fadare, O. O., & Witry, M. J. (2023) · Pharmacy · doi:10.3390/pharmacy11020042 · Cited by 6
Franco, R., & Serrano‐Marín, J. (2023) · Exploration of Neuroprotective Therapy · doi:10.37349/ent.2023.00035 · Cited by 6
Metadata
- Authors
- Charlesworth, C. J., Smit, E., Lee, D. S. H., Alramadhan, F., & Odden, M. C.
- Affiliations
- Oregon State University (US)
- Corresponding author
- Odden, Michelle C.
- Venue
- The Journals of Gerontology Series A: Biological Sciences and Medical Sciences
- Publisher
- Oxford University Press (OUP)
- Published
- 2015-03-01
- Volume
- 70
- Issue
- 8
- Pages
- 989-995
- ISSN
- 1079-5006 (ISSN-L)
- 1758-535X
- PMC
- PMC4573668
- OpenAlex
- W2137024248
- Cited by
- 570
- References
- 29
- Citations by year
- 2026: 28 · 2025: 33 · 2024: 49 · 2023: 54 · 2022: 43 · 2021: 119 · 2020: 64 · 2019: 66 · 2018: 42 · 2017: 27 · 2016: 32 · 2015: 12
- FWCI
- 18.80
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- The Journals of Gerontology Series A (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- American Heart Association
- National Institute on Aging (K01AG039387)
- Topics
- Health Sciences › Medicine › Geriatrics and Gerontology › Pharmaceutical Practices and Patient Outcomes
- Health Sciences › Medicine › Epidemiology › Chronic Disease Management Strategies
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Opioid Use Disorder Treatment
- Keywords
- polypharmacy, older adults, prescription drug use, potentially inappropriate medications, Beers criteria, temporal trends, chronic disease, functional limitations, activities of daily living, cognitive impairment, cardioprotective drugs, antidepressants, health care utilization, sociodemographic factors
- MeSH terms
- Aged, Aged, 80 and over, Female, Humans, Male, Time Factors, United States, Polypharmacy
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