Cost-effectiveness analysis of interventions to prevent cardiovascular disease in Vietnam
Abstract
BACKGROUND: Vietnam is in the process of an epidemiological transition, with cardiovascular disease (CVD) now ranked as the leading cause of death. The burden of CVD will continue to rise unless effective interventions for addressing its underlying risk factors are put in place. OBJECTIVES: To assess the costs, health effects and cost-effectiveness of a set of personal and non-personal prevention strategies to reduce CVD in Vietnam, including mass media campaigns for reducing consumption of salt and tobacco, drugs for lowering blood pressure or cholesterol, and combined pharmacotherapy for people at varying levels of absolute risk of a cardiovascular event. METHODS: WHO-CHOICE methods and analytical models were employed, using local data to estimate the costs, effects and cost-effectiveness of 12 population and individual interventions implemented singly or in combination. Costs were measured in Vietnamese Dong for the year 2007 (discounted at a rate of 3% per year), while health effects were expressed in age-weighted and discounted disability-adjusted life years (DALYs) averted. RESULTS: A health education programme to reduce salt intake (VND 1 945 002 or US$118 per DALY averted) and individual treatment of systolic blood pressure above 160 mmHg (VND 1 281 596 or US$78 per DALY averted) were found to be the most cost-effective measures for population- and individual-based approaches, respectively. Where budget is very limited, a mass media education programme on salt intake and a combination mass media programme addressing salt intake, cholesterol and tobacco should be selected first. If more resources become available, greatest population health gains can be achieved via individual treatment of systolic blood pressure and the absolute risk approach to CVD prevention. CONCLUSIONS: Contextualization of WHO-CHOICE using local data provides health decision-makers with more sound economic evidence for policy debates on prioritizing health interventions to reduce cardiovascular diseases in Vietnam. When used, cost-effectiveness analysis could increase efficiency in allocating scare resources.
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A few trials found that blood-pressure-lowering effects of sodium restriction were similar in subjects taking or not taking anti-hypertensives.
“a few trials found that BP-lowering effects of sodium restriction were similar in subjects taking or not taking anti-hypertensives.[10][11][12][13]”
From Global Sodium Consumption and Death from Cardiovascular Causes (2014) · cites this paper as [12]
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- Authors
- Ha, D. A., & Chisholm, D.
- Affiliations
- Boston University (US)
- Corresponding author
- Ha, D. A.
- Venue
- Health Policy and Planning
- Publisher
- Oxford University Press (OUP)
- Published
- 2010-09-15
- Volume
- 26
- Issue
- 3
- Pages
- 210-222
- ISSN
- 0268-1080 (ISSN-L)
- 1460-2237
- OpenAlex
- W2146439406
- Cited by
- 65
- References
- 59
- Citations by year
- 2026: 3 · 2025: 1 · 2024: 1 · 2023: 3 · 2022: 2 · 2021: 5 · 2020: 6 · 2019: 2 · 2018: 6 · 2017: 4 · 2016: 3 · 2015: 3 · 2014: 9 · 2013: 7 · 2012: 8
- FWCI
- 12.77
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Health Policy and Planning (publishedVersion)
- PubMed (publishedVersion)
- reroDoc Digital Library (submittedVersion)
- Funders
- Atlantic Philanthropies
- Vietnam Education Foundation
- Topics
- Social Sciences › Economics, Econometrics and Finance › Economics and Econometrics › Health Systems, Economic Evaluations, Quality of Life
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Health Promotion and Cardiovascular Prevention
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Risk Factors
- Keywords
- cardiovascular disease prevention, cost-effectiveness, salt reduction, mass media health campaigns, tobacco control, blood pressure treatment, cholesterol-lowering drugs, absolute cardiovascular risk, health education, disability-adjusted life years, WHO-CHOICE, Vietnam, resource allocation
- MeSH terms
- Adult, Aged, Aged, 80 and over, Cardiovascular Diseases, Cost-Benefit Analysis, Female, Health Status Indicators, Humans, Male, Middle Aged, Primary Prevention, Vietnam, Risk Reduction Behavior
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