Opa1 deficiency in a mouse model of autosomal dominant optic atrophy impairs mitochondrial morphology, optic nerve structure and visual function

Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development

Chen, H., Detmer, S. A., Ewald, A. J., Griffin, E. E., Fraser, S. E., & Chan, D. C. (2003) · The Journal of Cell Biology · doi:10.1083/jcb.200211046 · Cited by 2,601

OPA1 Controls Apoptotic Cristae Remodeling Independently from Mitochondrial Fusion

Frezza, C., Cipolat, S., Martins de Brito, O., Micaroni, M., Beznoussenko, G. V., Rudka, T., Bartoli, D., Polishuck, R. S., Danial, N. N., De Strooper, B., et al. (2006) · Cell · doi:10.1016/j.cell.2006.06.025 · Cited by 1,673

Nuclear gene OPA1, encoding a mitochondrial dynamin-related protein, is mutated in dominant optic atrophy

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Disruption of Fusion Results in Mitochondrial Heterogeneity and Dysfunction

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OPA1, encoding a dynamin-related GTPase, is mutated in autosomal dominant optic atrophy linked to chromosome 3q28

Alexander, C., Votruba, M., Pesch, U. E. A., Thiselton, D. L., Mayer, S., Moore, A., Rodriguez, M., Kellner, U., Leo-Kottler, B., Auburger, G., et al. (2000) · Nature Genetics · doi:10.1038/79944 · Cited by 1,330

OPA1 requires mitofusin 1 to promote mitochondrial fusion

Cipolat, S., de Brito, O. M., Dal Zilio, B., & Scorrano, L. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0407043101 · Cited by 1,300

Loss of OPA1 Perturbates the Mitochondrial Inner Membrane Structure and Integrity, Leading to Cytochrome c Release and Apoptosis

Olichon, A., Baricault, L., Gas, N., Guillou, E., Valette, A., Belenguer, P., & Lenaers, G. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.c200677200 · Cited by 1,168

Roles of the mammalian mitochondrial fission and fusion mediators Fis1, Drp1, and Opa1 in apoptosis

Lee, Y.-J., Jeong, S.-Y., Karbowski, M., Smith, C. L., & Youle, R. J. (2004) · Molecular Biology of the Cell · doi:10.1091/mbc.e04-04-0294 · Cited by 1,042

Regulation of mitochondrial morphology through proteolytic cleavage of OPA1

Ishihara, N., Fujita, Y., Oka, T., & Mihara, K. (2006) · The EMBO Journal · doi:10.1038/sj.emboj.7601184 · Cited by 899

Behavioral and functional analysis of mouse phenotype: SHIRPA, a proposed protocol for comprehensive phenotype assessment

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Rhomboid-7 over-expression results in Opa1-like processing and malfunctioning mitochondria

Rahman, M., & Kylsten, P. (2011) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2011.09.047 · Cited by 14

A uvs-5 Strain Is Deficient for a Mitofusin Gene Homologue, fzo1 , Involved in Maintenance of Long Life Span in Neurospora crassa

Kurashima, K., Chae, M. S., Inoue, H., Hatakeyama, S., & Tanaka, S. (2012) · Eukaryotic Cell · doi:10.1128/ec.00226-12 · Cited by 14

Mitochondrial Dynamics: Shaping Metabolic Adaptation

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Validating the RedMIT/GFP-LC3 Mouse Model by Studying Mitophagy in Autosomal Dominant Optic Atrophy Due to the OPA1Q285STOP Mutation

Diot, A., Agnew, T., Sanderson, J., Liao, C., Carver, J. G., das Neves, R. P., Gupta, R., Guo, Y., Waters, C. T., Seto, S., et al. (2018) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2018.00103 · Cited by 14

Retinal ganglion cell death and optic nerve degeneration by genetic ablation in adult mice

Cho, J. H., Mu, X., Wang, S. W., & Klein, W. H. (2008) · Experimental Eye Research · doi:10.1016/j.exer.2008.11.021 · Cited by 14

Merging mitochondria for neuronal survival

Manfredi, G., & Beal, M. F. (2007) · Nature Medicine · doi:10.1038/nm1007-1140 · Cited by 12

De la levure aux maladies neurodégénératives

Lenaers, G., Amati‐Bonneau, P., Delettre, C., Chevrollier, A., Verny, C., Miléa, D., Procaccio, V., Bonneau, D., Hamel, C., & Reynier, P. (2010) · médecine/sciences · doi:10.1051/medsci/20102610836 · Cited by 11

The use of animal models to study cell transplantation in neuropathic hearing loss

Abbas, L., & Rivolta, M. N. (2019) · Hearing Research · doi:10.1016/j.heares.2019.03.014 · Cited by 12

Red Light Irradiation In Vivo Upregulates DJ-1 in the Retinal Ganglion Cell Layer and Protects against Axotomy-Related Dendritic Pruning

Beirne, K., Freeman, T. J., Rôżanowska, M., & Votruba, M. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22168380 · Cited by 11

Aberrant Expression of Mitochondrial SAM Transporter SLC25A26 Impairs Oocyte Maturation and Early Development in Mice

Cheng, G., Guo, S., Yin, Y., Li, Y., He, X., & Zhou, L. (2022) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2022/1681623 · Cited by 12

Tourette Syndrome Risk Genes Regulate Mitochondrial Dynamics, Structure, and Function

Clarke, R. A., Furlong, T. M., & Eapen, V. (2021) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2020.556803 · Cited by 10

SARM1 loss protects retinal ganglion cells in a mouse model of autosomal dominant optic atrophy

Ding, C., Ndiaye, P. S., Campbell, S. R., Fry, M. Y., Gong, J., Wienbar, S. R., Gibbs, W., Morquette, P., Chao, L. H., Do, M. T. H., et al. (2025) · Journal of Clinical Investigation · doi:10.1172/jci191315 · Cited by 8

A mouse model of human mitofusin-2-related lipodystrophy exhibits adipose-specific mitochondrial stress and reduced leptin secretion

Mann, J. P., Duan, X., Patel, S., Tábara, L. C., Scurria, F., Álvarez-Guaita, A., Haider, A., Luijten, I. H. N., Page, M., Protasoni, M., et al. (2023) · eLife · doi:10.7554/elife.82283 · Cited by 10

Characterisation of a novel OPA1 splice variant resulting in cryptic splice site activation and mitochondrial dysfunction

Harvey, J. P., Yu‐Wai‐Man, P., & Cheetham, M. E. (2022) · European Journal of Human Genetics · doi:10.1038/s41431-022-01102-0 · Cited by 10

In Vivo Efficacy and Safety Evaluations of Therapeutic Splicing Correction Using U1 snRNA in the Mouse Retina

Swirski, S., May, O., Ahlers, M. T., Wissinger, B., Greschner, M., Jüschke, C., & Neidhardt, J. (2023) · Cells · doi:10.3390/cells12060955 · Cited by 10

Manipulation of Mitochondrial Plasticity Changes the Metabolic Competition Between “Foe” and “Friend” During Tumor Malignant Transformation

Tian, H., Zhang, B., Li, L., Wang, G., Li, H., & Zheng, J. (2020) · Frontiers in Oncology · doi:10.3389/fonc.2020.01692 · Cited by 10

Opa1 Deficiency Promotes Development of Retinal Vascular Lesions in Diabetic Retinopathy

Kim, D., Votruba, M., & Roy, S. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22115928 · Cited by 10

C. elegans as a powerful model for neurotoxicity assessment

Barbosa, D. J., Santos, I. C., Moyisyeyenko, T., Mendes, C., & Sobral, A. F. (2025) · NeuroToxicology · doi:10.1016/j.neuro.2025.07.009 · Cited by 10

Autosomal dominant optic atrophy caused by six novel pathogenic OPA1 variants and genotype–phenotype correlation analysis

Han, J., Li, Y., You, Y., Fan, K., & Lei, B. (2022) · BMC Ophthalmology · doi:10.1186/s12886-022-02546-0 · Cited by 9

Rapidly purified ganglion cells from neonatal mouse retinas allow studies of mitochondrial morphology and autophagy

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Clinico-pathological significance of Drp1 dysregulation and its correlation to apoptosis in oral cancer patients

Ghosh, A., Chatterjee, K., Chowdhury, A. R., & Barui, A. (2020) · Mitochondrion · doi:10.1016/j.mito.2020.03.003 · Cited by 9

Mitochondrial DNA content decreases during in vitro human embryo development: insights into mitochondrial DNA variation in preimplantation embryos donated for research

Pérez-Sánchez, M., Díez‐Juan, A., Beltrán, D., Mifsud, A., Mercader, A., Vidal, C., Labarta, E., Pellicer, A., Seli, E. U., & Santos, M. J. D. L. (2020) · F&S Science · doi:10.1016/j.xfss.2020.05.001 · Cited by 8

New avenues for therapy in mitochondrial optic neuropathies

Ng, V., Trigano, M., Freeman, T. J., Varricchio, C., Kandaswamy, S., Newland, B., Brancale, A., Rôżanowska, M., & Votruba, M. (2021) · Therapeutic Advances in Rare Disease · doi:10.1177/26330040211029037 · Cited by 8

‘Mitotherapy’ for Heart Failure

Sanchis‐Gomar, F., Lippi, G., & Lucía, A. (2016) · Trends in Molecular Medicine · doi:10.1016/j.molmed.2016.02.007 · Cited by 8

Mitochondrial reactive oxygen species regulate acetyl-CoA flux between cytokine production and fatty acid synthesis in effector T cells

Wu, B., Woo, J. S., Hasiakos, S., Pan, C., Cokus, S. J., Benincá, C., Stiles, L., Sun, Z., Pellegrini, M. A., Shirihai, O. S., et al. (2025) · Cell Reports · doi:10.1016/j.celrep.2025.115430 · Cited by 10

Optic Nerve Injury Enhanced Mitochondrial Fission and Increased Mitochondrial Density without Altering the Uniform Mitochondrial Distribution in the Unmyelinated Axons of Retinal Ganglion Cells in a Mouse Model

Tsuji, T., Murase, T., Konishi, Y., & Inatani, M. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24054356 · Cited by 7

Proteomic Identification of the SLC25A46 Interactome in Transgenic Mice Expressing SLC25A46-FLAG

Perivolidi, V.-I., Violitzi, F., Ioannidou, E., Rinotas, V. E., Stamatakis, G. M., Samiotaki, M. K., Panayotou, G., & Douni, E. K. (2022) · Journal of Proteome Research · doi:10.1021/acs.jproteome.1c00728 · Cited by 6

OPA1 mutations in Japanese patients suspected to have autosomal dominant optic atrophy

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Phenotypic and functional characterization of Bst+/- mouse retina

Riazifar, H., Sun, G., Wang, X., Rupp, A. C., Vemaraju, S., Ross‐Cisneros, F. N., Lang, R. A., Sadun, A. A., Hattar, S. S., Guan, M., et al. (2015) · Disease Models & Mechanisms · doi:10.1242/dmm.018176 · Cited by 7

Formulating treatment of major psychiatric disorders: algorithm targets the dominantly affected brain cell-types

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Characterization of a novel variant in the HR1 domain of MFN2 in a patient with ataxia, optic atrophy and sensorineural hearing loss

Sharma, G., Zaman, M., Sabouny, R., Joel, M., Martino, D., Martino, D., de Koning, A. P. J., Shutt, T. E., & Shutt, T. E. (2021) · F1000Research · doi:10.12688/f1000research.53230.1 · Cited by 23

Reply: Early-onset Behr syndrome due to compound heterozygous mutations in OPA1

Yu‐Wai‐Man, P., & Chinnery, P. F. (2014) · Brain · doi:10.1093/brain/awu187 · Cited by 6

Supplementary Pharmacotherapy for the Behavioral Abnormalities Caused by Stressors in Humans, Focused on Post-Traumatic Stress Disorder (PTSD)

Fessel, J. (2023) · Journal of Clinical Medicine · doi:10.3390/jcm12041680 · Cited by 6

Mitochondrial Dynamics in Health and Disease

Marı́n-Garcı́a, J. (2012) · Springer eBooks · doi:10.1007/978-1-4614-4599-9_17 · Cited by 5

Mitochondrial Dynamics

Tamura, Y., Iijima, M., & Sesaki, H. (2010) · Elsevier eBooks · doi:10.1016/b978-0-12-374145-5.00297-7 · Cited by 7

Mitochondrial fission, integrity and completion of mitophagy require separable functions of Vps13D in Drosophila neuronsPreprint

Insolera, R., Lőrincz, P., Wishnie, A. J., Juhász, G., & Collins, C. A. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.01.21.914523 · Cited by 5

Mitochondrial Quality Control in Alzheimer’s Disease: Insights from Caenorhabditis elegans Models

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OPA1 mutations in dominant optic atrophy: domain-specific defects in mitochondrial fusion and apoptotic regulation

Zhang, K., Zhang, W., Zhang, L., Hou, X., Tian, R., Hu, Z., Yin, L., & Hu, Z. (2025) · Journal of Translational Medicine · doi:10.1186/s12967-025-06471-w · Cited by 6

TAp73 regulates mitochondrial dynamics and multiciliated cell homeostasis through an OPA1 axis

Buckley, N. A., Craxton, A., Sun, X.-M., Panatta, E., Piñon, L., Beier, S., Kalmár, L., Llodrá, J., Morone, N., Amelio, I., et al. (2024) · Cell Death and Disease · doi:10.1038/s41419-024-07130-6 · Cited by 4

A Perspective on Accelerated Aging Caused by the Genetic Deficiency of the Metabolic Protein, OPA1

Erchova, I. A., Sun, S., & Votruba, M. (2021) · Frontiers in Neurology · doi:10.3389/fneur.2021.641259 · Cited by 4

Biochemical studies of the synaptic protein otoferlin

Meese, S. (2015) · doi:10.53846/goediss-5234 · Cited by 4

Marf- and Opa1-Dependent Formation of Mitochondrial Network Structure Is Required for Cell Growth and Subsequent Meiosis in Drosophila Males

Matsuo, T., Yamanaka, M., & Inoue, Y. H. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26209991 · Cited by 4

Mitochondrial Dynamics in Blood Cancer Development and Progression

Doshi, S., & Glytsou, C. (2025) · Current Pharmacology Reports · doi:10.1007/s40495-025-00431-0 · Cited by 4

Drosophila model to clarify the pathological significance of OPA1 in autosomal dominant optic atrophy

Nitta, Y., Osaka, J., Maki, R., Hakeda‐Suzuki, S., Suzuki, E., Ueki, S., Suzuki, T., & Sugie, A. (2023) · eLife · doi:10.7554/elife.87880 · Cited by 3

The Cellular and Molecular Mechanisms of Ovarian Aging

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ROMO1 and mitochondrial complex II/SDH are required for spare respiratory capacity and glucose homeostasis in mice

Wells, L., Yang, Q., Iorio, C., Peragerasingam, M., Campbell, Z. E., Ng, A. C.-H., Reeks, C., Yee, S., & Screaton, R. A. (2026) · Diabetologia · doi:10.1007/s00125-026-06728-z · Cited by 1

Loss of Mfn1 but not Mfn2 enhances adipogenesis

Mann, J. P., Tábara, L. C., Patel, S., Pushpa, P., Álvarez-Guaita, A., Dong, L., Haider, A., Lim, K., Tandon, P., Scurria, F., et al. (2024) · PLoS ONE · doi:10.1371/journal.pone.0306243 · Cited by 5

Mitochondrial Dynamics and Neurodegeneration

Mourier, A. (2016) · Springer eBooks · doi:10.1007/978-3-319-28637-2_7 · Cited by 3

The Molecular Genetics of Oogenesis

Zhai, F., Ma, X., Yan, L., & Qiao, J. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-813570-9.00007-3 · Cited by 4

Mitochondrial Changes Associated with Demyelination: Consequences for Axonal Integrity

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Novel in vivo models of autosomal optic atrophy reveal conserved pathological changes in neuronal mitochondrial structure and function

Strachan, E. L., Dillon, E., Sullivan, M., Glennon, J. C., Peyrel, A., Sarniguet, J., Dubois, K., Delprat, B., Kennedy, B. N., & O’Sullivan, N. C. (2025) · The FASEB Journal · doi:10.1096/fj.202403271r · Cited by 2

A role for Fis1 in dendritic development

Strucinska, K., Kneis, P., Pennington, T., Cizio, K., Szybowska, P. E., Morgan, A., Weertman, J., & Lewis, T. L. (2025) · Scientific Reports · doi:10.1038/s41598-025-33557-8 · Cited by 3

Genetic background modulates phenotypic expressivity in OPA1 mutated mice, relevance to DOA pathogenesis

Atamena, D., Gurram, V., Petsophonsakul, P., Khosrobakhsh, F., Arrázola, M. S., Botella, M., Wissinger, B., Szelechowski, M., & Belenguer, P. (2023) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2023.1241222 · Cited by 2

Opa1 and MT-Nd6 mutations induce early mitochondrial changes in the retina and prelaminar optic nerve of hereditary optic neuropathy mouse models

Bureau, J., Manero, F., Baris, O. R., Bodin, A., Verny, C., Chevrollier, A., Lenaers, G., & Codron, P. (2024) · Brain Communications · doi:10.1093/braincomms/fcae404 · Cited by 2

The crossroads of Leber hereditary optic neuropathy and autosomal dominant optic Atrophy: Clinical profiles of patients with coexisting pathogenic genetic variants

Halawani, M. A., & Badeeb, N. O. (2025) · American Journal of Ophthalmology Case Reports · doi:10.1016/j.ajoc.2025.102346 · Cited by 2

The endoplasmic reticulum protein FAM134B acts as a regulator of mitochondrial morphology

Maity, S., Gupta, A. D., Kamal, I. M., Das, R., Mondal, R., Tyagi, A., Sharma, D., Chakraborty, J., Chakrabarti, S., & Chakrabarti, O. (2025) · Journal of Cell Science · doi:10.1242/jcs.263920 · Cited by 2

Modeling Mitochondrial Dysfunction in Neurodegenerative Disease

Komen, J. C., & Thorburn, D. R. (2011) · Springer eBooks · doi:10.1007/978-0-85729-701-3_12 · Cited by 2

Mitochondrial Optic Neuropathies

Carelli, V., Morgia, C. L., & Klopstock, T. (2019) · Springer eBooks · doi:10.1007/978-3-030-05517-2_8 · Cited by 2

Cell-Free Analysis of Mitochondrial Fusion by Fluorescence Microscopy

Samanas, N. B., & Hoppins, S. C. (2020) · Methods in molecular biology · doi:10.1007/978-1-0716-0676-6_10 · Cited by 2

The molecular genetics of oogenesis

Zhai, F., Ma, X., Yan, L., & Qiao, J. (2023) · Elsevier eBooks · doi:10.1016/b978-0-323-91380-5.00011-3 · Cited by 2

Mitochondria Fusion and Fission

Bénard, G., Peng, G., & Karbowski, M. (2009) · Wiley eBooks · doi:10.1002/9780470015902.a0021577 · Cited by 2

Loss of Mfn1 but not Mfn2 enhances adipogenesisPreprint

Mann, J. P., Tábara, L. C., Álvarez-Guaita, A., Dong, L., Haider, A., Lim, K., Tandon, P., Minchin, J., O’Rahilly, S., Patel, S., et al. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.11.04.515167 · Cited by 2

Disrupted energy metabolism is associated with retinal ganglion cell degeneration in autosomal dominant optic atrophy

Kang, E. Y.-C., Tseng, Y.-J., Peng, W.-H., Hung, H.-C., Lin, P.-H., Montales, K. P., Sherman, E. A., Peregrin, J., Wang, E. H.-H., Kang, C., et al. (2026) · Science Advances · doi:10.1126/sciadv.adx7815 · Cited by 3

Rhesus macaques with an OPA1 mutation demonstrate features of autosomal dominant optic atrophy

Jaggers, T. N., Ripolles‐Garcia, A., Moshiri, A., Story, B. D., Wang, J., Chen, R., Moore, L. G., Teixeira, L. B. C., Shim, J., Raposo, A. C. S., et al. (2026) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2509165123 · Cited by 1

Targeting the OPA1 pathway in Autosomal Dominant Optic Atrophy (ADOA): 25 years from gene discovery to therapeutic strategy

Alavi, M. V. (2026) · Expert Opinion on Therapeutic Targets · doi:10.1080/14728222.2026.2671678 · Cited by 1

Models of Primary Mitochondrial Diseases with Neurodegeneration

Spirito, E., Rocco, A., & Maltecca, F. (2026) · Contemporary clinical neuroscience · doi:10.1007/978-3-032-18296-8_22 · Cited by 1

The Genetics of Mitochondrial Fusion and Fission

Chan, E. Y. L., Rujiviphat, J., & McQuibban, G. A. (2011) · Springer eBooks · doi:10.1007/978-94-007-1291-1_1 · Cited by 1

Focus on optic neuropathies due to mitochondrial dysfunction: molecular bases and putative therapies

Corral‐Debrinski, M., & Sahel, J. (2008) · Expert Review of Ophthalmology · doi:10.1586/17469899.3.6.599 · Cited by 1

Role of the Mitochondrial Fission Protein Drp1 in Synaptic Damage and Neurodegeneration

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Animal Models of Mitochondrial Diseases Associated with Nuclear Gene Mutations

Averina, O. A., Kuznetsova, S. A., Permyakov, O. A., & Владимирович, С. П. (2024) · Acta Naturae · doi:10.32607/actanaturae.25442 · Cited by 2

Defects in Mitochondrial Dynamics and Mitochondrial DNA Instability

Yu‐Wai‐Man, P., Lenaers, G., & Chinnery, P. F. (2012) · Springer eBooks · doi:10.1007/978-1-4614-3722-2_9 · Cited by 1

Mitochondria and Metabolism in Right Heart Failure

Bruns, D. R., & Walker, L. A. (2018) · InTech eBooks · doi:10.5772/intechopen.70450 · Cited by 1

OPA 1 and Its Clinical Implications

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Structural and functional analysis of the neuronal mitochondrial fission factor GDAP1 and its homolog GDAP1L1

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Developmental Regulation of Mitochondrial Function in Ovine Fetal Skeletal Muscle

Davies, K. (2018) · Apollo (University of Cambridge) · doi:10.17863/cam.22845 · Cited by 1

Loss of SARM1 protects against retinal ganglion cell degeneration in Autosomal Dominant Optic AtrophyPreprint

Ding, C., Ndiaye, P. S., Campbell, S. R., Fry, M. Y., Gong, J., Wienbar, S. R., Gibbs, W. S., Morquette, P., Chao, L. H., Do, M. T. H., et al. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.09.30.615936 · Cited by 1

Sociality shapes mitochondrial adaptations supporting hypoxia tolerancePreprint

Rossi, A., Ruwolt, M., Kakouri, P., Kosten, T., Kunz, S., Puchkov, D., Reznick, J., Purfürst, B., Omerbašić, D., Mendez-Aranda, D., et al. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.09.30.615914 · Cited by 1

Fis1 is required for the development of the dendritic mitochondrial network in pyramidal cortical neuronsPreprint

Strucinska, K., Kneis, P., Pennington, T., Cizio, K., Szybowska, P. E., Morgan, A., Weertman, J., & Lewis, T. L. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.01.07.631801 · Cited by 1

Ganglion Cell Diseases

Votruba, M. (2014) · Springer eBooks · doi:10.1007/978-3-540-69466-3_48

Manifestations of Drug Toxicity on Mitochondria in the Nervous System

Reynolds, I. J. (2008) · Wiley eBooks · doi:10.1002/9780470372531.ch8

Caracterização da função e da dinâmica mitocondrial em modelo animal de disfunção cardíaca associada ao infarto do miocárdio: efeitos do treinamento físico aeróbico

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Dinámica mitocondrial y sus implicaciones en la desregulación metabólica y en la neurodegeneración

Antonio Zorzano, A., Segalés, J., Hernández‐Álvarez, M. I., & Sorianello, E. M. (2012) · Monografías de la Real Academia Nacional de Farmacia

Retinal Neuronal Remodelling in a Model of Optic Atrophy

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Characterization of SLP-2 function in T lymphocytes

Christie, D. A. (2012) · Scholarship@Western (Western University)

Analyse bio-informatique du protéome mitochondrial et du spectre des mutations de la protéine Opa1

Ferré, M. (2009) · OpenGrey (Institut de l'Information Scientifique et Technique)

Hereditary Optic Neuropathies

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Inherited dominant optic neuropathy: from clinical studies to gene function and back again

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Clinical update in optic nerve disorders

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Genotype–phenotype correlations in mitochondrial optic neuropathies

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Mechanisms and Functions of Mitochondrial Dynamics

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Functional characterization of prohibitins by conditional inactivation in the mouse

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High-throughput siRNA Screen Identifies MTX2 as a Novel Mediator of Mitochondrial Morphology

Gaetz, M. (2014) · uO Research (University of Ottawa) · doi:10.20381/ruor-4048

Mitochondrial energetic metabolism in hereditary neuropathies associated with OPA1 and MFN2 genes mutations.

Guillet, V., & REYNIER, P. (2009) · OpenGrey (Institut de l'Information Scientifique et Technique)

Mitochondrial involvement in neuronal cell death

Gray, J. J. (2014) · Digital Commons - DU (University of Denver)

Functions and Kinetics of Mitochondrial Fusion and Fission in the Axon: a Quantitative Study

Yu, Y. (2015) · KiltHub Repository · doi:10.1184/r1/6717419

MECANISMOS DE ADAPTACIÓN DE LA ACTIVIDAD MITOCONDRIAL EN RESPUESTA A ESTRÉS

Gómez, A. T. (2016) · RiuNet (Universitat Politècnica de València) · doi:10.4995/thesis/10251/64873

Mitochondrial Dynamics and Its Implications in Metabolic Dysregulation and Neurodegeneration

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The Emerging Role of Mitochondrial Dynamics in Cardiovascular Disease

Marín-García, J. (2014) · Elsevier eBooks · doi:10.1016/b978-0-12-404599-6.00015-9

Hereditary Optic Neuropathies

Mackey, D. A. (2012) · doi:10.1093/med/9780195326147.003.0039

Genetic and Genomic Approaches for Understanding Retinal Diseases

Howell, G. R., & John, S. W. M. (2009) · Neuromethods · doi:10.1007/978-1-60761-541-5_3

Characterisation of a novel model of optic atrophy

Piechota, M. J. (2009) · ORCA Online Research @Cardiff (Cardiff University)

No retinal apoptosis in mouse model of Opa1 dominant optic atrophy despite visual loss

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