The DOI matches its Crossref record; 30 of the 30 references it cites were found in a registry or an index.
HOX gene expression is altered in the endometrium of women with endometriosis
Abstract
HOXA10 and HOXA11 are homeobox genes that function as transcription factors essential to embryonic development. We have recently described a role for each of these two genes in regulating endometrial development in the adult during the course of a menstrual cycle. Both Hoxa10 and Hoxa11 are essential for implantation in the mouse and appear to play a similar role in women. To investigate the role of HOX genes in the endometrium of women with endometriosis, quantitative Northern blot analysis was performed on the endometrium of 40 normal cycling controls and 40 patients with documented endometriosis. Patients with endometriosis failed to show the expected mid-luteal rise in HOX gene expression as demonstrated in the controls. Aberrant HOX gene expression suggests that altered development of the endometrium at the molecular level may contribute to the aetiology of infertility in patients with endometriosis.
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Cites
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Homeobox genes and axial patterning
McGinnis, W., & Krumlauf, R. (1992) · Cell · doi:10.1016/0092-8674(92)90471-n · Cited by 2,674
Hox genes in vertebrate development
Krumlauf, R. (1994) · Cell · doi:10.1016/0092-8674(94)90290-9 · Cited by 2,073
Shifren, J. L. (1996) · Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.81.8.3112 · Cited by 658
Aromatase expression in endometriosis.
Noble, L. S., Simpson, E. R., Johns, A., & Bulun, S. E. (1996) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.81.1.8550748 · Cited by 566 · cited 2×
“, 1990), aromatase (Noble et al., 1996), CA-125 (McBean and Brunstead, 1993), heat shock protein (Ota et al.”
BackgroundSexually dimorphic sterility phenotypes in HoxalO-deficient mice
Satokata, I., Benson, G., & Maas, R. (1995) · Nature · doi:10.1038/374460a0 · Cited by 524
Aberrant integrin expression in the endometrium of women with endometriosis
Lessey, B. A. (1994) · Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.79.2.643 · Cited by 514
Taylor, H. S., Arici, A., Olive, D., & Igarashi, P. (1998) · Journal of Clinical Investigation · doi:10.1172/jci1057 · Cited by 484
Self-citationTaylor, H. S., Vanden Heuvel, G. B., & Igarashi, P. (1997) · Biology of Reproduction · doi:10.1095/biolreprod57.6.1338 · Cited by 463
Self-citationHoxa 11 structure, extensive antisense transcription, and function in male and female fertility
Hsieh-Li, H. M., Witte, D. P., Weinstein, M., Branford, W., Li, H., Small, K., & Potter, S. S. (1995) · Development · doi:10.1242/dev.121.5.1373 · Cited by 393
Cited by
Giudice, L. C., & Kao, L. C. (2004) · The Lancet · doi:10.1016/s0140-6736(04)17403-5 · Cited by 3,166
Pathogenesis and pathophysiology of endometriosis
Burney, R. O., & Giudice, L. C. (2012) · Fertility and Sterility · doi:10.1016/j.fertnstert.2012.06.029 · Cited by 1,590
Burney, R. O., Talbi, S., Hamilton, A. E., Vo, K. C., Nyegaard, M., Nezhat, C. R., Lessey, B. A., & Giudice, L. C. (2007) · Endocrinology · doi:10.1210/en.2006-1692 · Cited by 735
Macer, M. L., & Taylor, H. S. (2012) · Obstetrics and Gynecology Clinics of North America · doi:10.1016/j.ogc.2012.10.002 · Cited by 681
Self-citationEndometriosis and infertility: a committee opinion
(2012) · Fertility and Sterility · doi:10.1016/j.fertnstert.2012.05.031 · Cited by 633
Metadata
- Authors
- Taylor, H. S.
- Venue
- Human Reproduction
- Publisher
- Oxford University Press (OUP)
- Published
- 1999-05-01
- Volume
- 14
- Issue
- 5
- Pages
- 1328-1331
- ISSN
- 0268-1161 (ISSN-L)
- 1460-2350
- OpenAlex
- W2150404274
- Cited by
- 373
- References
- 30
- FWCI
- 9.62
- Type
- journal article
- Language
- en
- Open access
- closed
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- Taylor, H. S. (1999). HOX gene expression is altered in the endometrium of women with endometriosis. Human Reproduction. https://doi.org/10.1093/humrep/14.5.1328
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
