The DOI matches its Crossref record; 24 of the 24 references it cites were found in a registry or an index.
Anti-Mullerian hormone-based approach to controlled ovarian stimulation for assisted conception
Abstract
BACKGROUND: Individualization of controlled ovarian stimulation (COS) for assisted conception is complicated by variable ovarian response to follicle stimulating hormone. We hypothesized that anti-Müllerian hormone (AMH), a predictor of oocyte yield, may facilitate treatment strategies for women undergoing COS, to optimize safety and clinical pregnancy rates. METHODS: Prospective cohort study of 538 patients in two centres with differential COS strategies based on a centralized AMH measurement. RESULTS: AMH was associated with oocyte yield after ovarian stimulation in both centres, and a 'reduced' AMH (1 to <5 pmol/l) was associated with a reduced clinical pregnancy rate. Women with a 'normal' AMH (5 to <15 pmol/l) treated with a long GnRH-agonist protocol (both centres) showed a low incidence of excess response (0%) and poor response (0%). In women with 'high' AMH (>15 pmol/l), the antagonist protocol eliminated the need for complete cryopreservation of embryos due to excess response (P < 0.001) and showed a higher fresh cycle clinical pregnancy rate than agonist cycles [OR 4.40 (95% CI 1.95-9.93), P < 0.001]. CONCLUSIONS: The use of circulating AMH to individualize treatment strategies for COS may result in reduced clinical risk, optimized treatment burden and maintained pregnancy rates, and is worthy of prospective randomized examination.
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Cites
Weenen, C. (2004) · Molecular Human Reproduction · doi:10.1093/molehr/gah015 · Cited by 1,285
A systematic review of tests predicting ovarian reserve and IVF outcome
Broekmans, F. J., Kwee, J., Hendriks, D. J., Mol, B. W., & Lambalk, C. B. (2006) · Human Reproduction Update · doi:10.1093/humupd/dml034 · Cited by 1,258
Serum anti-Mullerian hormone levels: a novel measure of ovarian reserve
van Rooij, I. A. J. (2002) · Human Reproduction · doi:10.1093/humrep/17.12.3065 · Cited by 951
The Science behind 25 Years of Ovarian Stimulation for in Vitro Fertilization
Macklon, N. S., Stouffer, R. L., Giudice, L. C., & Fauser, B. C. J. M. (2006) · Endocrine Reviews · doi:10.1210/er.2005-0015 · Cited by 562
Broer, S. L., Mol, B. W. J., Hendriks, D., & Broekmans, F. J. M. (2009) · Fertility and Sterility · doi:10.1016/j.fertnstert.2007.12.013 · Cited by 546
Serum anti-Mullerian hormone throughout the human menstrual cycle
La Marca, A., Stabile, G., Artenisio, A. C., & Volpe, A. (2006) · Human Reproduction · doi:10.1093/humrep/del291 · Cited by 532
Nelson, S. M., Yates, R. W., & Fleming, R. (2007) · Human Reproduction · doi:10.1093/humrep/dem204 · Cited by 391
Self-citationClinical management of low ovarian response to stimulation for IVF: a systematic review
Tarlatzis, B. C. (2003) · Human Reproduction Update · doi:10.1093/humupd/dmg007 · Cited by 365
A mild treatment strategy for in-vitro fertilisation: a randomised non-inferiority trial
Heijnen, E. M., Eijkemans, M. J., De Klerk, C., Polinder, S., Beckers, N. G., Klinkert, E. R., Broekmans, F. J., Passchier, J., Te Velde, E. R., Macklon, N. S., et al. (2007) · The Lancet · doi:10.1016/s0140-6736(07)60360-2 · Cited by 349
GnRH antagonist in assisted reproduction: a Cochrane review
Al-Inany, H. (2002) · Human Reproduction · doi:10.1093/humrep/17.4.874 · Cited by 345
Cited by
The physiology and clinical utility of anti-Müllerian hormone in women
Dewailly, D., Andersen, C. Y., Balen, A., Broekmans, F., Dilaver, N., Fanchin, R., Griesinger, G., Kelsey, T. W., La Marca, A., Lambalk, C., et al. (2014) · Human Reproduction Update · doi:10.1093/humupd/dmt062 · Cited by 1,049
Self-citationLa Marca, A., & Sunkara, S. K. (2014) · Human Reproduction Update · doi:10.1093/humupd/dmt037 · Cited by 586
The endocrinology of the menstrual cycle
Barbieri, R. L. (2014) · Methods in Molecular Biology · doi:10.1007/978-1-4939-0659-8_7 · Cited by 196
Streuli, I., de Ziegler, D., Gayet, V., Santulli, P., Bijaoui, G., de Mouzon, J., & Chapron, C. (2012) · Human Reproduction · doi:10.1093/humrep/des274 · Cited by 171
Bourdon, M., Raad, J., Dahan, Y., Marcellin, L., Maignien, C., Even, M., Pocate-Cheriet, K., Lamau, M. C., Santulli, P., & Chapron, C. (2018) · PLOS ONE · doi:10.1371/journal.pone.0202399 · Cited by 42
Metadata
- Authors
- Nelson, S. M., Yates, R. W., Lyall, H., Jamieson, M., Traynor, I., Gaudoin, M., Mitchell, P., Ambrose, P., & Fleming, R.
- Venue
- Human Reproduction
- Publisher
- Oxford University Press (OUP)
- Published
- 2008-12-26
- Volume
- 24
- Issue
- 4
- Pages
- 867-875
- ISSN
- 0268-1161 (ISSN-L)
- 1460-2350
- OpenAlex
- W2161729104
- Cited by
- 339
- References
- 24
- FWCI
- 23.09
- Type
- journal article
- Language
- en
- Open access
- closed
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- Nelson, S. M., Yates, R. W., Lyall, H., Jamieson, M., Traynor, I., Gaudoin, M., Mitchell, P., Ambrose, P., & Fleming, R. (2008). Anti-Mullerian hormone-based approach to controlled ovarian stimulation for assisted conception. Human Reproduction. https://doi.org/10.1093/humrep/den480
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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