ESHRE special interest group for andrology basic semen analysis course: a continued focus on accuracy, quality, efficiency and clinical relevance
Abstract
ESHRE has been running courses for basic semen analysis since 1994 and course material has been updated regularly in response to new findings and publications. Following publication of the 5th edition of the WHO laboratory manual, entitled WHO Laboratory Manual for the Examination and Processing of Human Semen (WHO5), the Subcommittee for training of the ESHRE Special Interest Group for Andrology evaluated potential amendments to its course. In respect of the updated ESHRE course, there are eight particular areas of discourse that are reviewed (i) maintaining the four-class differential motility count allowing distinction between rapid and slow progressive sperm for assisted reproduction technology. (ii) Maintaining the four-category assessment for sperm morphology with calculation of the teratozoospermic index. (iii) Continuing to advocate the use of three categories of results: 'normal', 'borderline' and 'abnormal' with respect to the clinical interpretation of the data. (iv) Presenting clear and unequivocal methods for performing assessments e.g. morphology. (v) Correcting the inconsistencies in WHO5, some of which are actually erroneous. (vi) Reducing the requirements for substantial extra work for what are unestablished improvements in accuracy and/or precision in the final results. (vii) Presentation of logical methods of sperm preparation. (viii) Discussion of the suddenly changed limits between fertile and subfertile men.
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Sperm progressive motility is a strong predictor of fertility outcome.
“There is clinical evidence supporting sperm progressive motility being a strong predictor of fertility outcome (Barratt et al., 2011”
From Good practice in laboratory diagnostic andrology: Association of Reproductive and Clinical Scientists guidelines 2024 (2024) · cites this paper as Barratt et al., 2011
Cites
The evaluation of morphological characteristics of human spermatozoa according to stricter criteria
Menkveld, R., Stander, F. S. H., Kotze, T. J. V., Kruger, T. F., & Zyl, J. A. V. (1990) · Human Reproduction · doi:10.1093/oxfordjournals.humrep.a137150 · Cited by 677 · see citing works
Self-citationBarratt, C. L. R., McLeod, I. D., Dunphy, B. C., & Cooke, I. D. (1992) · Human Reproduction · doi:10.1093/oxfordjournals.humrep.a137834 · Cited by 37 · see citing works
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van den Hoven, L., van Vrouwerff, N. J., Dijkstra, I. M., Weeteling, J., Brinkman, J. W., Eliveld, J., & Wetzels, A. M. M. (2025) · Andrology · doi:10.1111/andr.13684 · Cited by 4 · see citing works
Gallagher, M. T., Roxburgh, E., Bennett, G., Parker, S., Kirkman-Brown, J. C., & Association of Reproductive and Clinical Scientists (2024) · Reproductive BioMedicine Online · doi:10.1016/j.rbmo.2024.104373 · Cited by 2 · see citing works
- Authors
- Barratt, C. L. R., Bjorndahl, L., Menkveld, R., & Mortimer, D.
- Affiliations
- University of Dundee (GB)
- Stellenbosch University (ZA)
- Corresponding author
- Barratt, C. L. R.
- Venue
- Human Reproduction
- Publisher
- Oxford University Press (OUP)
- Published
- 2011-09-28
- Volume
- 26
- Issue
- 12
- Pages
- 3207-3212
- ISSN
- 0268-1161 (ISSN-L)
- 1460-2350
- OpenAlex
- W2099950831
- Cited by
- 127
- References
- 2
- Citations by year
- 2026: 6 · 2025: 8 · 2024: 9 · 2023: 10 · 2022: 19 · 2021: 12 · 2020: 12 · 2019: 11 · 2018: 7 · 2017: 4 · 2016: 4 · 2015: 5 · 2014: 4 · 2013: 9 · 2012: 6
- FWCI
- 6.81
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Human Reproduction (publishedVersion)
- PubMed (publishedVersion)
- Discovery Research Portal (University of Dundee) (publishedVersion)
- SUNScholar (Stellenbosch University) (submittedVersion)
- Topics
- Health Sciences › Medicine › Reproductive Medicine › Sperm and Testicular Function
- Health Sciences › Medicine › Reproductive Medicine › Reproductive Health and Technologies
- Health Sciences › Health Professions › General Health Professions › Male Reproductive Health Studies
- Keywords
- semen analysis, sperm morphology assessment, sperm preparation, male fertility, subfertile men, assisted reproduction
- MeSH terms
- Education, Continuing, Humans, Male, Public Opinion, Semen, World Health Organization, Andrology, Semen Analysis, Reproductive Health
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