The DOI matches its Crossref record; 184 of the 184 references it cites were found in a registry or an index.
Contemporary genetic technologies and female reproduction
Open accessAbstract
† Genetics of disorders of the female reproductive system Endometriosis † Predictors of oocyte quality and successful embryo development Cumulus gene expression profiling 'Omics' technologies for embryo assessment † Conclusions background: The Fifth Evian Annual Reproduction (EVAR) Workshop Meeting discussed knowledge regarding contemporary genetics in female reproduction.methods: Specialist reproductive medicine clinicians and geneticists delivered presentations based on published literature and current research.The content of this report is based on the expert presentations and subsequent group discussions that took place during this Workshop.results: Numerous ovarian genes with a role in infertility have been identified.Future challenges for genetic screening of patients, such as those with polycystic ovary syndrome, primary ovarian insufficiency or endometriosis, include the identification of high-throughput strategies and how to apply these findings to infertile patients.The identification of high-quality embryos in IVF using objective technologies remains a high priority in order to facilitate single-embryo transfer.Gene expression profiling of cumulus cells surrounding the oocyte, and proteomic and metabolomic approaches in embryo culture media may significantly improve non-invasive embryo quality assessment.conclusions: The way forward in advancing the knowledge of genes involved in reproduction was considered to be through genomewide association studies involving large numbers of patients.Establishing international collaboration is required to enable the application of such technologies in sufficient numbers of patients.Key words: genes and female reproductive pathologies / embryo assessment / endometriosis / metabolomics / transcriptomics * The Fifth Evian Annual Reproduction (EVAR) Workshop Meeting (16 -17 April 2010) was organized to discuss contemporary genetic technologies and female reproduction.The content of this manuscript is based on the presentations and discussions during this EVAR Workshop Meeting.
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1 retracted
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Cited by
Integrative analysis reveals regulatory programs in endometriosis
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Metadata
- Authors
- The Evian Annual Reproduction (EVAR) Workshop Group 2010, Fauser, B. C. J. M., Diedrich, K., Bouchard, P., Dominguez, F., Matzuk, M., Franks, S., Hamamah, S., Simon, C., Devroey, P., Ezcurra, D., & Howles, C. M.
- Venue
- Human Reproduction Update
- Publisher
- Oxford University Press (OUP)
- Published
- 2011-09-06
- Volume
- 17
- Issue
- 6
- Pages
- 829-847
- ISSN
- 1355-4786 (ISSN-L)
- 1460-2369
- OpenAlex
- W2120078601
- Cited by
- 349
- References
- 184
- FWCI
- 10.29
- Type
- journal article
- Language
- en
- Open access
- bronze
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