The DOI matches its Crossref record; 10 of the 10 references it cites were found in a registry or an index.
Association of the metabolic syndrome with both vigorous and moderate physical activity
Abstract
BACKGROUND: Cross-sectional relationships between moderate and vigorous physical activity and the metabolic syndrome (MS) were examined in the Whitehall II study of civil servants (age 45-68 years). We assessed cardiovascular fitness and body mass index (BMI) as possible mediators of the observed association. METHODS: Measures of 2-hour glucose, systolic blood pressure, fasting triglycerides, waist-hip ratio, and high density lipoprotein (HDL) cholesterol were obtained in 5153 white European participants. Participants in the most adverse sex-specific quintile for three or more of these risk factors were classified as having MS. Self-reported leisure-time physical activity was categorized into separate moderate and vigorous activity classes. BMI and resting heart rate (HR) were used to estimate body fatness and cardiovascular fitness respectively. RESULTS: The odds ratios (95% CI) for having the metabolic syndrome in the top categories of vigorous and moderate activity were 0.52 (95% CI: 0.40, 0.67) and 0.78 (95% CI: 0.63, 0.96) respectively, adjusted for age, sex, smoking, alcohol intake, socioeconomic status, and other activity. Adjustment for BMI and resting HR substantially attenuated both of the above associations. CONCLUSIONS: Moderate and vigorous physical leisure-time activity are each associated with reduced risk of being classified with MS independently of age, smoking, and high alcohol intake. Both vigorous and moderate activities may be beneficial to the MS cluster of risk factors among middle-aged populations. Reduced BMI and increased cardiovascular fitness may be important mediators of this association for both intensities of activity.
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Compendium of Physical Activities: Classification of energy costs of human physical activities
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Physical Activity and the Incidence of Coronary Heart Disease
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A meta-analysis of physical activity in the prevention of coronary heart disease.
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Self-citationManson, J. E., Hu, F. B., Rich-Edwards, J. W., Colditz, G. A., Stampfer, M. J., Willett, W. C., Speizer, F. E., & Hennekens, C. H. (1999) · New England Journal of Medicine · doi:10.1056/nejm199908263410904 · Cited by 1,005
Physical fitness and activity as separate heart disease risk factors: a meta-analysis
WILLIAMS, P. T. (2001) · Medicine & Science in Sports & Exercise · doi:10.1097/00005768-200105000-00012 · Cited by 724
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Self-citationPhysical activity and cardiovascular disease: evidence for a dose response
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Cited by
Metabolic Syndrome and Insulin Resistance: Underlying Causes and Modification by Exercise Training
Roberts, C. K., Hevener, A. L., & Barnard, R. J. (2013) · Comprehensive Physiology · doi:10.1002/cphy.c110062 · Cited by 831
Exercise and the Cardiovascular System: Clinical Science and Cardiovascular Outcomes
Lavie, C. J., Arena, R., Swift, D. L., Johannsen, N. M., Sui, X., Lee, D.-C., Earnest, C. P., Church, T. S., O’Keefe, J. H., Milani, R. V., et al. (2015) · Circulation Research · doi:10.1161/circresaha.117.305205 · Cited by 782
The role of insufficient sleep and circadian misalignment in obesity
Chaput, J.-P., McHill, A. W., Cox, R. C., Broussard, J. L., Dutil, C., da Costa, B. G. G., Sampasa-Kanyinga, H., & Wright, K. P. (2023) · Nature Reviews Endocrinology · doi:10.1038/s41574-022-00747-7 · Cited by 649
Sedentary Behavior, Physical Activity, and the Metabolic Syndrome among U.S. Adults
Ford, E. S., Kohl, H. W., Mokdad, A. H., & Ajani, U. A. (2005) · Obesity Research · doi:10.1038/oby.2005.65 · Cited by 549
Physical activity in prevention and treatment of the metabolic syndrome
Lakka, T. A., & Laaksonen, D. E. (2007) · Applied Physiology, Nutrition, and Metabolism · doi:10.1139/h06-113 · Cited by 482
Metadata
- Authors
- Rennie, K., McCarthy, N., Yazdgerdi, S., Marmot, M., & Brunner, E.
- Venue
- International Journal of Epidemiology
- Publisher
- Oxford University Press (OUP)
- Published
- 2003-08
- Volume
- 32
- Issue
- 4
- Pages
- 600-606
- ISSN
- 0300-5771 (ISSN-L)
- 1464-3685
- OpenAlex
- W2096239185
- Cited by
- 319
- References
- 10
- FWCI
- 6.88
- Type
- journal article
- Language
- en
- Open access
- closed
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