The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
A Modified Polyriboinosinic-Polyribocytidylic Acid Complex That Induces Interferon in Primates
Abstract
A comlex of polyriboinosinic-polyribocytidylic acid (poly I-poly C) with poly-L-lysine and carboxymethylcellulose has been prepared. This complex is five to 10 times as resistant to hydrolysis by primate serum as the parent poly I-poly C. It has a thermal denaturation temperature about 40 C higher than that of poly I-poly C. The complex induces significant levels of serum interferon in monkeys and chimpanzees under conditions in which poly I-poly C itself induces no interferon.
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Citations
Cites
Inducers of interferon and host resistance. II. Multistranded synthetic polynucleotide complexes.
Field, A. K., Tytell, A. A., Lampson, G. P., & Hilleman, M. R. (1967) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.58.3.1004 · Cited by 708
INHIBITION OF TUMOR GROWTH BY POLYINOSINIC-POLYCYTIDYLIC ACID
Levy, H. B., Law, L. W., & Rabson, A. S. (1969) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.62.2.357 · Cited by 181
Self-citationInhibition of Biologic Activity of Poly I: Poly C by Human Plasma
Nordlund, J. J., Wolff, S., & Levy, H. B. (1970) · Experimental Biology and Medicine · doi:10.3181/00379727-133-34492 · Cited by 110
Self-citationEvaluation of an Interferon Inducer in Viral Respiratory Disease
Hill, D. A. (1972) · JAMA · doi:10.1001/jama.1972.03190350025006 · Cited by 62
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Vaccine Adjuvants: Putting Innate Immunity to Work
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Modern Subunit Vaccines: Development, Components, and Research Opportunities
Moyle, P. M., & Toth, I. (2013) · ChemMedChem · doi:10.1002/cmdc.201200487 · Cited by 464
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Garland, K. M., Sheehy, T. L., & Wilson, J. T. (2022) · Chemical Reviews · doi:10.1021/acs.chemrev.1c00750 · Cited by 357
Microbial synthesis of poly(ε-lysine) and its various applications
SHIH, I., SHEN, M., & VAN, Y. (2006) · Bioresource Technology · doi:10.1016/j.biortech.2004.08.012 · Cited by 354
An Overview of Vaccine Adjuvants: Current Evidence and Future Perspectives
Facciolà, A., Visalli, G., Laganà, A., & Di Pietro, A. (2022) · Vaccines · doi:10.3390/vaccines10050819 · Cited by 316
Metadata
- Authors
- Levy, H. B., Baer, G., Baron, S., Buckler, C. E., Gibbs, C. J., Iadarola, M. J., London, W. T., & Rice, J.
- Venue
- Journal of Infectious Diseases
- Publisher
- Oxford University Press (OUP)
- Published
- 1975-10-01
- Volume
- 132
- Issue
- 4
- Pages
- 434-439
- ISSN
- 0022-1899 (ISSN-L)
- 1537-6613
- OpenAlex
- W2037260140
- Cited by
- 270
- References
- 4
- FWCI
- 3.77
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: A Modified Polyriboinosinic-Polyribocytidylic Acid Complex That Induces Interferon in Primates. https://app.cochat.ai/papers/10.1093/infdis/132.4.434
- The paper
- Levy, H. B., Baer, G., Baron, S., Buckler, C. E., Gibbs, C. J., Iadarola, M. J., London, W. T., & Rice, J. (1975). A Modified Polyriboinosinic-Polyribocytidylic Acid Complex That Induces Interferon in Primates. Journal of Infectious Diseases. https://doi.org/10.1093/infdis/132.4.434
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
