The DOI matches its Crossref record.
A Sensitive and Specific DNA Probe to Identify Enteroaggregative Escherichia coli, a Recently Discovered Diarrheal Pathogen
Abstract
The epidemiologic significance of enteroaggregative Escherichia coli (EAggEC) as a diarrheal pathogen has only recently come under study. Although EAggEC has been associated with persistent diarrhea in infants in some developing countries, additional studies are clearly needed. Until now, the only means of identifying EAggEC strains has been the cumbersome HEp-2 cell adhesion assay. The isolation and cloning of a 1-kilobase fragment from the plasmid of EAggEC strain 17-2 is described. This probe is 89% sensitive and 99% specific for EAggEC identification. Thus, this probe should greatly facilitate epidemiologic studies assessing the importance of EAggEC as a diarrheal pathogen.
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Cited by
Heterogeneity of Enteroaggregative Escherichia Coli Virulence Demonstrated
Nataro, J. P., Yikang, D., Cookson, S., Cravioto, A., Savarino, S. J., Guers, L. D., Levine, M. M., & Tacket, C. O. (1995) · Journal of Infectious Diseases · doi:10.1093/infdis/171.2.465 · Cited by 326
Self-citationNataro, J. P., Deng, Y., Maneval, D. R., German, A. L., Martin, W. C., & Levine, M. M. (1992) · Infection and Immunity · doi:10.1128/iai.60.6.2297-2304.1992 · Cited by 303
Self-citationSteiner, T. S., Lima, A. A. M., Nataro, J. P., & Guerrant, R. L. (1998) · The Journal of Infectious Diseases · doi:10.1086/513809 · Cited by 288
Okhuysen, P. C., & DuPont, H. L. (2010) · The Journal of Infectious Diseases · doi:10.1086/654895 · Cited by 112
Metadata
- Authors
- Baudry, B., Savarino, S. J., Vial, P., Kaper, J. B., & Levine, M. M.
- Venue
- Journal of Infectious Diseases
- Publisher
- Oxford University Press (OUP)
- Published
- 1990-06-01
- Volume
- 161
- Issue
- 6
- Pages
- 1249-1251
- ISSN
- 0022-1899 (ISSN-L)
- 1537-6613
- OpenAlex
- W2141066076
- Cited by
- 332
- References
- 0
- FWCI
- 8.80
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: A Sensitive and Specific DNA Probe to Identify Enteroaggregative Escherichia coli, a Recently Discovered Diarrheal Pathogen. https://app.cochat.ai/papers/10.1093/infdis/161.6.1249
- The paper
- Baudry, B., Savarino, S. J., Vial, P., Kaper, J. B., & Levine, M. M. (1990). A Sensitive and Specific DNA Probe to Identify Enteroaggregative Escherichia coli, a Recently Discovered Diarrheal Pathogen. Journal of Infectious Diseases. https://doi.org/10.1093/infdis/161.6.1249
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
