The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
T Cell Response to Mycobacterium tuberculosis
Abstract
The T cell-mediated acquired immune response to infection with Mycobacterium tuberculosis, both in humans and in experimental models in the mouse, is a complex event believed to involve a variety of T cell subsets that manifest themselves in numerous functions, including protection, delayed-type hypersensitivity, cytolysis, and the establishment of a state of memory immunity. These functions in turn involve the secretion of an array of cytokines, several of which direct cells of the monocyte/macrophage axis to contain and destroy the invading bacilli. This article reviews the development of these ideas, both from clinical experience and from basic research in animal models. In addition, the newly emerging hypothesis that the secreted or export proteins of M. tuberculosis are the key protective antigens leading to the initial expression of acquired specific resistance to this organism is examined.
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Citations
Cites
Properties of proteins MPB64, MPB70, and MPB80 of Mycobacterium bovis BCG
Harboe, M., Nagai, S., Patarroyo, M. E., Torres, M. L., Ramirez, C., & Cruz, N. (1986) · Infection and Immunity · doi:10.1128/iai.52.1.293-302.1986 · Cited by 207
Cited by
The pathology and pathogenesis of paratuberculosis in ruminants and other species
Clarke, C. J. (1997) · Journal of Comparative Pathology · doi:10.1016/s0021-9975(97)80001-1 · Cited by 502
Glucocorticoid use, other associated factors, and the risk of tuberculosis
Jick, S. S., Lieberman, E. S., Rahman, M. U., & Choi, H. K. (2006) · Arthritis Care & Research · doi:10.1002/art.21705 · Cited by 477
The temporal expression profile of Mycobacterium tuberculosis infection in mice
Talaat, A. M., Lyons, R., Howard, S. T., & Johnston, S. A. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0306023101 · Cited by 363
ESAT-6 proteins: protective antigens and virulence factors?
Brodin, P., Rosenkrands, I., Andersen, P., Cole, S. T., & Brosch, R. (2004) · Trends in Microbiology · doi:10.1016/j.tim.2004.09.007 · Cited by 312
Self-citationMycobacterium boviss Infection and Tuberculosis in Cattle
Pollock, J. M., & Neill, S. D. (2002) · The Veterinary Journal · doi:10.1053/tvjl.2001.0655 · Cited by 296
Metadata
- Authors
- Orme, I. M., Andersen, P., & Boom, W. H.
- Venue
- Journal of Infectious Diseases
- Publisher
- Oxford University Press (OUP)
- Published
- 1993-06-01
- Volume
- 167
- Issue
- 6
- Pages
- 1481-1497
- ISSN
- 0022-1899 (ISSN-L)
- 1537-6613
- OpenAlex
- W2004604338
- Cited by
- 423
- References
- 1
- FWCI
- 17.78
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: T Cell Response to Mycobacterium tuberculosis. https://app.cochat.ai/papers/10.1093/infdis/167.6.1481
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- Orme, I. M., Andersen, P., & Boom, W. H. (1993). T Cell Response to Mycobacterium tuberculosis. Journal of Infectious Diseases. https://doi.org/10.1093/infdis/167.6.1481
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
