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Influenza Vaccination of Health Care Workers in Long-Term-Care Hospitals Reduces the Mortality of Elderly Patients
Open accessAbstract
Vaccination of health care workers (HCWs) is recommended as a strategy for preventing influenza in elderly patients in long-term care. However, there have been no controlled studies to show whether this approach is effective. During the winter of 1994-1995, 1059 patients in 12 geriatric medical long-term-care sites, randomized for vaccination of HCWs, were studied. In hospitals where HCWs were offered vaccination, 653 (61%) of 1078 were vaccinated. Vaccination of HCWs was associated with reductions in total patient mortality from 17% to 10% (odds ratio [OR], 0.56; 95% confidence interval [CI], 0.40-0.80) and in influenza-like illness (OR, 0.57; 95% CI, 0.34-0.94). Vaccination of patients was not associated with significant effects on mortality (OR, 1.15; 95% CI, 0.81-1.64). Results of this study support recommendations for vaccination against influenza of HCWs in long-term geriatric care. Vaccination of frail elderly long-term-care patients may not give clinically worthwhile benefits.
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Cited by
2013 IDSA Clinical Practice Guideline for Vaccination of the Immunocompromised Host
Rubin, L. G., Levin, M. J., Ljungman, P., Davies, E. G., Avery, R., Tomblyn, M., Bousvaros, A., Dhanireddy, S., Sung, L., Keyserling, H., et al. (2014) · Clinical Infectious Diseases · doi:10.1093/cid/cit684 · Cited by 1,613
Harper, S. A., Bradley, J. S., Englund, J. A., File, T. M., Gravenstein, S., Hayden, F. G., McGeer, A. J., Neuzil, K. M., Pavia, A. T., Tapper, M. L., et al. (2009) · Clinical Infectious Diseases · doi:10.1086/598513 · Cited by 647
Complications of Viral Influenza
Rothberg, M. B., Haessler, S. D., & Brown, R. B. (2008) · The American Journal of Medicine · doi:10.1016/j.amjmed.2007.10.040 · Cited by 456
Influenza in the acute hospital setting
Salgado, C. D., Farr, B. M., Hall, K. K., & Hayden, F. G. (2002) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(02)00221-9 · Cited by 417
Infectious respiratory illnesses and their impact on healthcare workers: a review
Low, J., & Wilder-Smith, A. (2005) · Annals of the Academy of Medicine, Singapore · doi:10.47102/annals-acadmedsg.v34n1p105 · Cited by 46
Metadata
- Authors
- Potter, J., Stott, D. J., Roberts, M. A., Elder, A. G., O'Donnell, B., Knight, P. V., & Carman, W. F.
- Venue
- Journal of Infectious Diseases
- Publisher
- Oxford University Press (OUP)
- Published
- 1997-01-01
- Volume
- 175
- Issue
- 1
- Pages
- 1-6
- ISSN
- 0022-1899 (ISSN-L)
- 1537-6613
- OpenAlex
- W2321609861
- Cited by
- 660
- References
- 0
- FWCI
- 16.98
- Type
- journal article
- Language
- en
- Open access
- bronze
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- CoChat. (2026). Citation check: Influenza Vaccination of Health Care Workers in Long-Term-Care Hospitals Reduces the Mortality of Elderly Patients. https://app.cochat.ai/papers/10.1093/infdis/175.1.1
- The paper
- Potter, J., Stott, D. J., Roberts, M. A., Elder, A. G., O'Donnell, B., Knight, P. V., & Carman, W. F. (1997). Influenza Vaccination of Health Care Workers in Long-Term-Care Hospitals Reduces the Mortality of Elderly Patients. Journal of Infectious Diseases. https://doi.org/10.1093/infdis/175.1.1
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
