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Cited by 722

The DOI matches its Crossref record; 29 of the 29 references it cites were found in a registry or an index.

The increasing use of silver-based products as antimicrobial agents: a useful development or a cause for concern?

Open access
Chopra, Ian·2007·Journal of Antimicrobial Chemotherapy

Abstract

Silver first gained regulatory approval for use as an antimicrobial agent in the early 20th century, but its usage diminished with the introduction of antibiotics in the 1940s. Recently, however, topical silver has gained popularity once again, principally in the management of open wounds. This has been largely due to the spread of methicillin-resistant Staphylococcus aureus and the resultant reduction in first-line antibiotic prescribing. The increase in the use of topical silver has raised issues concerning silver resistance, together with questions about the standardization of antimicrobial testing methods for silver. Issues related to silver product testing include a failure to establish standard procedures for determining MIC values, an absence of recognized breakpoints, a lack of conformity in the way different products release silver and variations in the effects of microbiological media on silver release and the measurement of inhibitory activity. The clinical incidence of silver resistance remains low, and emergence of resistance can be minimized if the level of silver ions released from products is high and the bactericidal activity rapid.

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Crossref · 10.1093/jac/dkm006

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Metadata

Authors
Chopra, I.
Venue
Journal of Antimicrobial Chemotherapy
Published
2007-02-16
Volume
59
Issue
4
Pages
587-590
ISSN
  • 0305-7453 (ISSN-L)
  • 1460-2091
OpenAlex
W2146818200
Cited by
722
References
29
FWCI
14.12
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: The increasing use of silver-based products as antimicrobial agents: a useful development or a cause for concern? https://app.cochat.ai/papers/10.1093/jac/dkm006
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Chopra, I. (2007). The increasing use of silver-based products as antimicrobial agents: a useful development or a cause for concern? Journal of Antimicrobial Chemotherapy. https://doi.org/10.1093/jac/dkm006

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.