Optimizing clinical decision support alerts in electronic medical records: a systematic review of reported strategies adopted by hospitals
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Objective: To identify and summarize the current internal governance processes adopted by hospitals, as reported in the literature, for selecting, optimizing, and evaluating clinical decision support (CDS) alerts in order to identify effective approaches. Materials and methods: Databases (Medline, Embase, CINAHL, Scopus, Web of Science, IEEE Xplore Digital Library, CADTH, and WorldCat) were searched to identify relevant papers published from January 2010 to April 2020. All paper types published in English that reported governance processes for selecting and/or optimizing CDS alerts in hospitals were included. Results: Eight papers were included in the review. Seven papers focused specifically on medication-related CDS alerts. All papers described the use of a multidisciplinary committee to optimize alerts. Other strategies included the use of clinician feedback, alert data, literature and drug references, and a visual dashboard. Six of the 8 papers reported evaluations of their CDS alert modifications following the adoption of optimization strategies, and of these, 5 reported a reduction in alert rate. Conclusions: A multidisciplinary committee, often in combination with other approaches, was the most frequent strategy reported by hospitals to optimize their CDS alerts. Due to the limited number of published processes, variation in system changes, and evaluation results, we were unable to compare the effectiveness of different strategies, although employing multiple strategies appears to be an effective approach for reducing CDS alert numbers. We recommend hospitals report on descriptions and evaluations of governance processes to enable identification of effective strategies for optimization of CDS alerts in hospitals.
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Effective governance of CDS has been demonstrated in other institutions, resulting in the transition of alert and reminder content to other more appropriate areas in the EHR, downgrading the severity of alerts, and assessing the effect of CDS on clinician behavior and patient care.
“Effective governance of CDS has been demonstrated in other institutions, resulting in the transition of alert and reminder content to other more appropriate areas in the EHR, downgrading the severity of alerts (often leading to them no longer firing), 38 39 and assessing the effect of CDS on clinician behavior and patient care. 40 41”
From Qualitative Study of Inpatient Hospital Medicine Interruptive Alerts and Clinical Decision Support (2026) · cites this paper as [38]
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Qualitative Study of Inpatient Hospital Medicine Interruptive Alerts and Clinical Decision Support
Khan, A., & Schnipper, J. (2026) · Applied Clinical Informatics · doi:10.1055/a-2955-9555
- Authors
- Van Dort, B. A., Zheng, W. Y., Sundar, V., & Baysari, M. T.
- Affiliations
- Discipline of Biomedical Informatics and Digital Health, School of Medical Sciences, Charles Perkins Centre, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia
- The University of Sydney (AU)
- Macquarie University (AU)
- Venue
- Journal of the American Medical Informatics Association
- Publisher
- Oxford University Press (OUP)
- Published
- 2020-11-13
- Volume
- 28
- Issue
- 1
- Pages
- 177-183
- ISSN
- 1067-5027 (ISSN-L)
- 1527-974X
- PMC
- PMC7810441
- OpenAlex
- W3103574025
- Cited by
- 75
- References
- 4
- Citations by year
- 2026: 16 · 2025: 23 · 2024: 11 · 2023: 16 · 2022: 5 · 2021: 4
- FWCI
- 0.95
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Licence
- academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model (vor)
- Locations
- Journal of the American Medical Informatics Association (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- The University of Sydney
- Topics
- Health Sciences › Health Professions › Health Information Management › Electronic Health Records Systems
- Health Sciences › Medicine › Health Informatics › Artificial Intelligence in Healthcare and Education
- Health Sciences › Medicine › Surgery › Healthcare Technology and Patient Monitoring
- Keywords
- clinical decision support alerts, electronic health records, multidisciplinary committee, clinician feedback, clinical decision support
- MeSH terms
- Alert Fatigue, Health Personnel, Hospital Information Systems, Humans, Decision Support Systems, Clinical, Medical Order Entry Systems, Electronic Health Records
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