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Cited by 87Medication Adherence and ComplianceMaternal and Neonatal HealthcarePregnancy and Medication Impact

Pill Count Adherence to Prenatal Multivitamin/Mineral Supplement Use among Low-Income Women

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Jasti, Sunitha, Siega-Riz, Anna Maria, Cogswell, Mary E., Hartzema, Abraham G., Bentley, Margaret E.·2005·The Journal of Nutrition
DOI 10.1093/jn/135.5.1093
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Abstract

In the United States, the prevalence of third trimester anemia among low-income pregnant women is 29% and has not improved since the 1980s. Although low adherence has been linked to the ineffectiveness of iron supplementation programs, data regarding adherence to supplementation in low-income women are currently lacking. Hence this study was conducted to better understand the factors associated with adherence to the use of iron-containing prenatal multivitamin/mineral supplements among low-income pregnant women. Adherence to supplement use was assessed by pill counts among 244 pregnant women of 867 women who were initially randomized to receive 1 of 3 prenatal supplements. All women received care at a public prenatal clinic. Maternal characteristics associated with adherence were identified using predictive modeling. Women took 74% of supplements as prescribed. Adherence was higher among non-Hispanic white women than among non-Hispanic black women (79% vs. 72%, P </= 0.01). Interactions of ethnicity with age group, smoking status, and prior supplement use were significant. Multivariate regression analysis stratified by ethnicity revealed that among the white women education beyond high school, unmarried status, nulligravidity, and smoking were positively associated with adherence. In contrast, among the black women, supplement use 3 mo prior to current pregnancy and no loss of appetite were positively associated with adherence. Further research investigating the influence of cultural factors is necessary to better understand adherence to supplement use and the differences in adherence among ethnic groups.

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  1. [1]1. U.S. Department of Health and Human Services (2000) With under- standing and improving health and objectives for improving health. In: Healthy People 2010, 2nd ed., pp. 19-37-19-39.
  2. [36]36. Institute of Medicine, Food and Nutrition Board (1993) Iron deficiency anemia: guidelines for prevention, detection and management among U.S. chil- dren and women of childbearing age. Washington, DC: National Academy Press, 1993.

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Authors
Jasti, S., Siega-Riz, A. M., Cogswell, M. E., Hartzema, A. G., & Bentley, M. E.
Affiliations
  • Queens College, CUNY (US)
  • Centers for Disease Control and Prevention (US)
  • University of Florida Health (US)
  • University of North Carolina at Chapel Hill (US)
Corresponding author
Jasti, Sunitha
ORCID
Venue
The Journal of Nutrition
Publisher
Elsevier BV
Published
2005-05
Volume
135
Issue
5
Pages
1093-1101
ISSN
0022-3166 (ISSN-L)
DOI
10.1093/jn/135.5.1093
OpenAlex
W1945883111
Cited by
87
References
43
Citations by year
2025: 5 · 2024: 1 · 2023: 1 · 2022: 2 · 2021: 4 · 2020: 7 · 2019: 4 · 2018: 1 · 2017: 4 · 2016: 9 · 2015: 6 · 2014: 5 · 2013: 4 · 2012: 4
FWCI
2.38
Type
journal article
Language
en
Open access
Licence
Locations
  • Journal of Nutrition (publishedVersion)
  • PubMed (publishedVersion)
Funders
Centers for Disease Control and Prevention
Topics
  • Health Sciences › Medicine › Family Practice › Medication Adherence and Compliance
  • Health Sciences › Health Professions › General Health Professions › Maternal and Neonatal Healthcare
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Pregnancy and Medication Impact
Keywords
supplement adherence, pill count, low-income pregnant women, iron supplementation, third trimester anemia, ethnic differences, racial disparities, smoking, predictors of adherence
MeSH terms
Adolescent, Adult, Ethnicity, Female, Gestational Age, Humans, Iron, Minerals, Parity, Patient Compliance, Poverty, Pregnancy, Prenatal Care, United States, Vitamins, Patient Selection, Dietary Supplements

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