The DOI matches its Crossref record.
AIDS-Antiviral Sulfolipids From Cyanobacteria (Blue-Green Algae)
Abstract
A recently developed tetrazolium-based microculture assay was used to screen extracts of cultured cyanobacteria (blue-green algae) for inhibition of the cytopathic effects of the human immunodeficiency virus (HIV-1), which is implicated as a causative agent of AIDS. A number of extracts were found to be remarkably active against the AIDS virus. A new class of HIV-1-inhibitory compounds, the sulfonic acid-containing glycolipids, was discovered through the use of the microculture assay to guide the fractionation and purification process. The pure compounds were active against HIV-1 in cultured human lymphoblastoid CEM, MT-2, LDV-7, and C3-44 cell lines in the tetrazolium assay as well as in p24 viral protein and syncytium formation assays.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
Marine cyanobacteria—a prolific source of natural products
Burja, A. M., Banaigs, B., Abou-Mansour, E., Grant Burgess, J., & Wright, P. C. (2001) · Tetrahedron · doi:10.1016/s0040-4020(01)00931-0 · Cited by 841
Suganya, T., Varman, M., Masjuki, H. H., & Renganathan, S. (2016) · Renewable and Sustainable Energy Reviews · doi:10.1016/j.rser.2015.11.026 · Cited by 793
Bioactive compounds from cyanobacteria and microalgae: an overview
Singh, S., Kate, B. N., & Banerjee, U. C. (2005) · Critical Reviews in Biotechnology · doi:10.1080/07388550500248498 · Cited by 619
Microalgae in Human and Animal Nutrition
Becker, W. (2003) · Handbook of Microalgal Culture · doi:10.1002/9780470995280.ch18 · Cited by 613
Exploring the potential of microalgae for new biotechnology applications and beyond: a review
Rizwan, M., Mujtaba, G., Memon, S. A., Lee, K., & Rashid, N. (2018) · Renewable and Sustainable Energy Reviews · doi:10.1016/j.rser.2018.04.034 · Cited by 578
Metadata
- Authors
- Gustafson, K. R., Cardellina, J. H., Fuller, R. W., Weislow, O. S., Kiser, R. F., Snader, K. M., Patterson, G. M. L., & Boyd, M. R.
- Venue
- JNCI Journal of the National Cancer Institute
- Publisher
- Oxford University Press (OUP)
- Published
- 1989-08-16
- Volume
- 81
- Issue
- 16
- Pages
- 1254-1258
- ISSN
- 0027-8874 (ISSN-L)
- 1460-2105
- OpenAlex
- W2096813500
- Cited by
- 301
- References
- 0
- FWCI
- 6.01
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: AIDS-Antiviral Sulfolipids From Cyanobacteria (Blue-Green Algae). https://app.cochat.ai/papers/10.1093/jnci/81.16.1254
- The paper
- Gustafson, K. R., Cardellina, J. H., Fuller, R. W., Weislow, O. S., Kiser, R. F., Snader, K. M., Patterson, G. M. L., & Boyd, M. R. (1989). AIDS-Antiviral Sulfolipids From Cyanobacteria (Blue-Green Algae). JNCI Journal of the National Cancer Institute. https://doi.org/10.1093/jnci/81.16.1254
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
