Bioactive compounds from cyanobacteria and microalgae: an overview
Abstract
Cyanobacteria (blue-green algae) are photosynthetic prokaryotes used as food by humans. They have also been recognized as an excellent source of vitamins and proteins and as such are found in health food stores throughout the world. They are also reported to be a source of fine chemicals, renewable fuel and bioactive compounds. This potential is being realized as data from research in the areas of the physiology and chemistry of these organisms are gathered and the knowledge of cyanobacterial genetics and genetic engineering increased. Their role as antiviral, anti-tumour, antibacterial, anti-HIV and a food additive have been well established. The production of cyanobacteria in artificial and natural environments has been fully exploited. In this review the use of cyanobacteria and microalgae, production processes and biosynthesis of pigments, colorants and certain bioactive compounds are discussed in detail. The genetic manipulation of cyanobacteria and microalgae to improve their quality are also described at length.
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Cyclic or linear peptides and depsipeptides isolated from cyanobacteria are protease inhibitors used for the treatment of strokes, coronary artery occlusions and pulmonary emphysema.
“Several cyclic or linear peptides and depsipeptides isolated from cyanobacteria are protease inhibitors, used for the treatment of diseases such as strokes, coronary artery occlusions and pulmonary emphysema (Skulberg, 2004, Singh et al., 2005).”
From Microalgae Metabolites: A Rich Source for Food and Medicine (2019) · cites this paper as Singh et al., 2005
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- Authors
- Singh, S., Kate, B. N., & Banerjee, U. C.
- Affiliations
- National Institute of Pharmaceutical Education and Research (IN)
- Venue
- Critical Reviews in Biotechnology
- Publisher
- Informa UK Limited
- Published
- 2005-01
- Volume
- 25
- Issue
- 3
- Pages
- 73-95
- ISSN
- 0738-8551 (ISSN-L)
- 1549-7801
- OpenAlex
- W2093366831
- Cited by
- 619
- References
- 83
- Citations by year
- 2026: 16 · 2025: 18 · 2024: 27 · 2023: 31 · 2022: 42 · 2021: 40 · 2020: 52 · 2019: 43 · 2018: 40 · 2017: 34 · 2016: 36 · 2015: 41 · 2014: 45 · 2013: 36 · 2012: 23
- FWCI
- 0.97
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Critical Reviews in Biotechnology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Physical Sciences › Energy › Renewable Energy, Sustainability and the Environment › Algal biology and biofuel production
- Health Sciences › Medicine › Pharmacology › Microbial Natural Products and Biosynthesis
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Biotechnology › Microbial Metabolism and Applications
- Keywords
- cyanobacteria, microalgae, bioactive compounds, cyanobacterial pigments, colorants, antiviral agents, anticancer agents, antibacterial agents, anti-HIV compounds, food additives, renewable fuels
- MeSH terms
- Cyanobacteria, Biological Factors, Biological Products, Biotechnology, Eukaryota
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