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Cited by 371

The DOI matches its Crossref record; 135 of the 135 references it cites were found in a registry or an index.

Genetic and Hormonal Risk Factors in Breast Cancer

Martin, A.-M.·2000·Journal of the National Cancer Institute

Abstract

Breast cancer poses a serious public health problem, and it is hoped that identification of genetic and environmental factors that contribute to the development of breast cancer will enhance prevention efforts. Two breast cancer susceptibility genes (BRCA1 and BRCA2) have been identified, and germline mutations in these genes are thought to account for between 5% and 10% of all breast cancer cases. Current findings suggest that mutations in other highly penetrant genes may play an important role in breast cancer susceptibility, and studies aimed at the isolation of these genes are under way. In addition, common variants in a number of gene classes are thought to act as low-penetrance susceptibility alleles, and efforts to identify and characterize these variants are under way. This review discusses the genetic components of susceptibility to breast cancer from the standpoint of both human genetics and rat models.

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Metadata

Authors
Martin, A.-M.
Venue
Journal of the National Cancer Institute
Published
2000-07-19
Volume
92
Issue
14
Pages
1126-1135
ISSN
  • 0027-8874 (ISSN-L)
  • 1460-2105
OpenAlex
W2104356108
Cited by
371
References
135
FWCI
11.32
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Genetic and Hormonal Risk Factors in Breast Cancer. https://app.cochat.ai/papers/10.1093/jnci/92.14.1126
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Martin, A.-M. (2000). Genetic and Hormonal Risk Factors in Breast Cancer. Journal of the National Cancer Institute. https://doi.org/10.1093/jnci/92.14.1126

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.