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Behavioral Intervention for Cancer Treatment Side Effects
Abstract
The use of increasingly aggressive methods of cancer treatment during the last 20 years has brought clinical attention to the need for more effective management of pain, nausea, and other aversive side effects of state-of-the-art cancer therapy. One of the most promising approaches to effective management is nonpharmacologic intervention based on behavioral research and theory. The purpose of this review is to examine the effectiveness of behavioral intervention methods in the control of aversive side effects of cancer treatments. Fifty-four published studies using a variety of research designs were identified for review. Results indicated the following: 1) Behavioral intervention can effectively control anticipatory nausea and vomiting in adult and pediatric cancer patients undergoing chemotherapy; however, the evidence for the efficacy of behavioral intervention to control post-chemotherapy nausea and vomiting is less clear. 2) Behavioral intervention integrating several behavioral methods can ameliorate anxiety and distress associated with invasive medical treatments. 3) Although a variety of behavioral methods have been shown to reduce acute treatment-related pain, there is increasing evidence that these methods are not equally effective. Hypnotic-like methods, involving relaxation, suggestion, and distracting imagery, hold the greatest promise for pain management. Unfortunately, research is scant on the use of behavioral intervention to control prolonged pain associated with invasive medical procedures. It is clear that the application of behavioral theory and methods has an important place in the care of patients undergoing invasive cancer treatments.
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“Furthermore, meta-analyses [33], narrative reviews [34,35], and randomized clinical studies [36–39] all support the potential clinical utility of hypnosis with surgical patients.”
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Metadata
- Authors
- Redd, W. H., Montgomery, G. H., & DuHamel, K. N.
- Affiliations
- Icahn School of Medicine at Mount Sinai (US)
- Corresponding author
- Redd, W. H.
- Venue
- JNCI Journal of the National Cancer Institute
- Publisher
- Oxford University Press (OUP)
- Published
- 2001-06-06
- Volume
- 93
- Issue
- 11
- Pages
- 810-823
- ISSN
- 0027-8874 (ISSN-L)
- 1460-2105
- OpenAlex
- W2104277553
- Cited by
- 231
- References
- 109
- Citations by year
- 2026: 2 · 2025: 3 · 2024: 4 · 2023: 6 · 2022: 6 · 2021: 5 · 2020: 5 · 2019: 6 · 2018: 10 · 2017: 12 · 2016: 7 · 2015: 18 · 2014: 12 · 2013: 10 · 2012: 13
- FWCI
- 0.86
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- JNCI Journal of the National Cancer Institute (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Oncology › Cancer survivorship and care
- Health Sciences › Medicine › Surgery › Nausea and vomiting management
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Pediatric Pain Management Techniques
- Keywords
- behavioral interventions, cancer treatment side effects, chemotherapy-induced nausea and vomiting, anticipatory nausea and vomiting, pain management, relaxation, distraction, anxiety and distress, non-pharmacological treatment, pediatric cancer patients, invasive procedures
- MeSH terms
- Anxiety, Behavior Therapy, Humans, Nausea, Neoplasms, Pain, Relaxation Therapy, Stress, Psychological, Vomiting
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