The DOI matches its Crossref record; 24 of the 24 references it cites were found in a registry or an index.
Change in Cognitive Function After Chemotherapy: a Prospective Longitudinal Study in Breast Cancer Patients
Abstract
Some breast cancer survivors experience cognitive decline following chemotherapy. We prospectively examined changes in cognitive performance among high-risk breast cancer patients who had received high-dose chemotherapy with cyclophosphamide, thiotepa, and carboplatin (CTC group; n = 28) or standard-dose chemotherapy with 5-fluorouracil, epirubicin, and cyclophosphamide (FEC group; n = 39); stage-I breast cancer patients who had received no systemic chemotherapy (no-CT group; n = 57); and healthy control subjects (n = 60). All patients underwent neuropsychologic testing before and 6 months after treatment (12-month interval); control subjects underwent repeated testing over a 6-month interval. No differences in cognitive functioning between the four groups were observed at the first assessment. More of the CTC group than the control subjects experienced a deterioration in cognitive performance over time (25% versus 6.7%; odds ratio [OR] = 5.3, 95% confidence interval [CI] = 1.3 to 21.2, P = .02). No such difference was observed for the FEC or the no-CT groups (FEC versus control: OR = 2.2, 95% CI = 0.5 to 9.1, P = .27; no-CT versus Control: OR = 2.2, 95% CI = 0.6 to 8.0; P = .21). Some cytotoxic treatment for breast cancer affects cognition in a subset of women.
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Self-citationCognitive Function in Breast Cancer Patients Receiving Adjuvant Chemotherapy
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Cited by
Prevalence, mechanisms, and management of cancer-related cognitive impairment
Janelsins, M. C., Kesler, S. R., Ahles, T. A., & Morrow, G. R. (2014) · International Review of Psychiatry · doi:10.3109/09540261.2013.864260 · Cited by 745
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Self-citationCarreira, H., Williams, R., Müller, M., Harewood, R., Stanway, S., & Bhaskaran, K. (2018) · JNCI: Journal of the National Cancer Institute · doi:10.1093/jnci/djy177 · Cited by 416
Chemotherapy-Related Cognitive Dysfunction
Wefel, J. S., & Schagen, S. B. (2012) · Current Neurology and Neuroscience Reports · doi:10.1007/s11910-012-0264-9 · Cited by 398
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Metadata
- Authors
- Schagen, S. B., Muller, M. J., Boogerd, W., Mellenbergh, G. J., & van Dam, F. S. A. M.
- Venue
- JNCI: Journal of the National Cancer Institute
- Publisher
- Oxford University Press (OUP)
- Published
- 2006-12-06
- Volume
- 98
- Issue
- 23
- Pages
- 1742-1745
- ISSN
- 0027-8874 (ISSN-L)
- 1460-2105
- OpenAlex
- W2135750130
- Cited by
- 295
- References
- 24
- FWCI
- 13.15
- Type
- journal article
- Language
- en
- Open access
- closed
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