Cited by 1,408Cancer survivorship and careMental Health Treatment and AccessCancer-related cognitive impairment studies

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Prevalence of Depression in Patients With Cancer

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Massie, M. J.·2004·Journal of the National Cancer Institute Monographs

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Abstract

Depression is the psychiatric syndrome that has received the most attention in individuals with cancer. The study of depression has been a challenge because symptoms occur on a broad spectrum that ranges from sadness to major affective disorder and because mood change is often difficult to evaluate when a patient is confronted by repeated threats to life, is receiving cancer treatments, is fatigued, or is experiencing pain. Although many research groups have assessed depression in cancer patients since the 1960s, the reported prevalence (major depression, 0%-38%; depression spectrum syndromes, 0%-58%) varies significantly because of varying conceptualizations of depression, different criteria used to define depression, differences in methodological approaches to the measurement of depression, and different populations studied. Depression is highly associated with oropharyngeal (22%-57%), pancreatic (33%-50%), breast (1.5%-46%), and lung (11%-44%) cancers. A less high prevalence of depression is reported in patients with other cancers, such as colon (13%-25%), gynecological (12%-23%), and lymphoma (8%-19%). This report reviews the prevalence of depression in cancer patients throughout the course of cancer.

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Authors: Massie, M. J.
Affiliations: Memorial Sloan Kettering Cancer Center (US)
Corresponding author: Massie, M. J.
Venue: Journal of the National Cancer Institute Monographs
Publisher: Oxford University Press (OUP)
Published: 2004-07-01
Volume: 2004
Issue: 32
Pages: 57-71
ISSN: 1052-6773 (ISSN-L)
DOI: 10.1093/jncimonographs/lgh014
OpenAlex: W2111457041
Cited by: 1,408
References: 117
Citations by year: 2026: 34 · 2025: 33 · 2024: 35 · 2023: 62 · 2022: 102 · 2021: 74 · 2020: 65 · 2019: 79 · 2018: 62 · 2017: 63 · 2016: 82 · 2015: 76 · 2014: 81 · 2013: 119 · 2012: 104
FWCI: 2.05
Type: journal article
Language: en
Open access: bronze
doi.org
Locations: JNCI Monographs (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Oncology › Cancer survivorship and care
Health Sciences › Medicine › Psychiatry and Mental health › Mental Health Treatment and Access
Health Sciences › Medicine › Oncology › Cancer-related cognitive impairment studies
Keywords: depression, cancer patients, prevalence, major depressive disorder, oropharyngeal cancer, pancreatic cancer, breast cancer, lung cancer, cancer-related depression, mood assessment
MeSH terms: Depressive Disorder, Fatigue, Humans, Neoplasms, Pain, Risk Factors, Sex Factors, Prevalence

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