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Cited by 365

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Plant nitrate transporters: from gene function to application

Open access
Fan, Xiaorong, Naz, Misbah, Fan, Xiaoru, Xuan, Wei, Miller, Anthony J, Xu, Guohua·2017·Journal of Experimental Botany
DOI 10.1093/jxb/erx011
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Abstract

Plant nitrate transporters were first identified and functionally characterized more than 20 years ago.They are encoded at least by four gene families, NRT1 (NPF), NRT2, CLC, and SLAC1/SLAH.In this review, we overview the functions of the nitrate transporters in relation to their potential use as targets for improving crop nitrogen use efficiency.These functions include their roles in root architecture and nutrient acquisition; vacuole nitrate and protein storage; nutrient allocation from source to sink; sensing both abiotic and biotic stresses; the ionic balance of nitrate with potassium, chloride and cellular pH; and the circadian clock-regulated carbon and nitrogen balance.We provide and discuss some examples of the use of nitrate transporter genes and their regulators in improving plant growth and development, nitrogen use efficiency, and resistance to some abiotic stresses.We propose several strategies for effectively using nitrate transporters to achieve higher crop yields and nitrogen use efficiency by using gene transformation or genome editing or molecular marker-assisted breeding.

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Research works printed but not linked: 46

  1. 2016, Phenotyping two tomato genotypes with different nitrogen use efficiency, Plant Physiology and Biochemistry, 107, 21, 10.1016/j.plaphy.2016.04.021 · doi:10.1016/j.plaphy.2016.04.021
  2. 2016, Members of BTB gene family of scaffold proteins suppress nitrate uptake and nitrogen use efficiency, Plant Physiology, 171, 1523
  3. 2012, Functional assessment of the Medicago truncatula NIP/LATD protein demonstrates that it is a high-affinity nitrate transporter, Plant Physiology, 160, 906, 10.1104/pp.112.196444 · doi:10.1104/pp.112.196444
  4. 2012, A deletion in the nitrate high affinity transporter NRT2.1 alters metabolomic and transcriptomic responses to Pseudomonas syringae, Plant Signaling & Behavior, 7, 619, 10.4161/psb.20430 · doi:10.4161/psb.20430
  5. 2016, Agronomic nitrogen-use efficiency of rice can be increased by driving OsNRT2.1 expression with the OsNAR2.1 promoter, Plant Biotechnology Journal, 14, 1705, 10.1111/pbi.12531 · doi:10.1111/pbi.12531
  6. 2016, Shoot-to-root mobile transcription factor HY5 coordinates plant carbon and nitrogen acquisition, Current Biology, 26, 640, 10.1016/j.cub.2015.12.066 · doi:10.1016/j.cub.2015.12.066
  7. 2014, Proanthocyanidin oxidation of Arabidopsis seeds is altered in mutant of the high-affinity nitrate transporter NRT2.7, Journal of Experimental Botany, 65, 885, 10.1093/jxb/ert481 · doi:10.1093/jxb/ert481
  8. 2016, N availability modulates the role of NPF3.1, a gibberellin transporter, in GA-mediated phenotypes in Arabidopsis, Planta, 244, 1315, 10.1007/s00425-016-2588-1 · doi:10.1007/s00425-016-2588-1
  9. 2009, The Arabidopsis nitrate transporter NRT1.7, expressed in phloem, is responsible for source-to-sink remobilization of nitrate, The Plant Cell, 21, 2750, 10.1105/tpc.109.067603 · doi:10.1105/tpc.109.067603
  10. 2007, Comparing nitrate storage and remobilization in two rice cultivars that differ in their nitrogen use efficiency, Journal of Experimental Botany, 58, 1729, 10.1093/jxb/erm033 · doi:10.1093/jxb/erm033
  11. 2005, A comparison of nitrate transport in four different rice (Oryza sativa L.) cultivars, Science in China Series C: Life Sciences, 48, 897
  12. 2013, Altered expression of the PTR/NRT1 homologue OsPTR9 affects nitrogen utilization efficiency, growth and grain yield in rice, Plant Biotechnology Journal, 11, 446, 10.1111/pbi.12031 · doi:10.1111/pbi.12031
  13. 2016, Alleviation of proton toxicity by nitrate uptake specifically depends on nitrate transporter 1.1 in Arabidopsis, The New Phytologist, 211, 149, 10.1111/nph.13892 · doi:10.1111/nph.13892
  14. 2011, Spatial expression and regulation of rice high-affinity nitrate transporters by nitrogen and carbon status, Journal of Experimental Botany, 62, 2319, 10.1093/jxb/erq403 · doi:10.1093/jxb/erq403
  15. 2014, Targeting novel chemical and constitutive primed metabolites against Plectosphaerella cucumerina, The Plant Journal, 78, 227, 10.1111/tpj.12465 · doi:10.1111/tpj.12465
  16. 2015, Nitrate signalling: functions of a nitrate transceptor, Nature Plants, 1, 15021, 10.1038/nplants.2015.21 · doi:10.1038/nplants.2015.21
  17. 2015, Abiotic stresses downregulate key genes involved in nitrogen uptake and assimilation in Brassica juncea L, PLoS One, 10, e0143645, 10.1371/journal.pone.0143645 · doi:10.1371/journal.pone.0143645
  18. 2016, Cloning of chrysanthemum high affinity nitrate transporter family (CmNRT2) and characterization of CmNRT2.1, Scientific Reports, 6, 23462, 10.1038/srep23462 · doi:10.1038/srep23462
  19. 2016, Nitrogen use efficiency is mediated by vacuolar nitrate sequestration capacity in roots of Brassica napus, Plant Physiology, 170, 1684, 10.1104/pp.15.01377 · doi:10.1104/pp.15.01377
  20. 2011, Evidence for a nitrate-independent function of the nitrate sensor NRT1.1 in Arabidopsis thaliana, Journal of Plant Research, 124, 425, 10.1007/s10265-010-0385-7 · doi:10.1007/s10265-010-0385-7
  21. 2013, Two phloem nitrate transporters, NRT1.11 and NRT1.12, are important for redistributing xylem-borne nitrate to enhance plant growth, Plant Physiology, 163, 844, 10.1104/pp.113.226563 · doi:10.1104/pp.113.226563
  22. 2015, Knockdown of the partner protein OsNAR2.1 for high-affinity nitrate transport represses lateral root formation in a nitrate-dependent manner, Scientific Reports, 5, 18192, 10.1038/srep18192 · doi:10.1038/srep18192
  23. 2009, The bZIP transcription factors HY5 and HYH are positive regulators of the main nitrate reductase gene in Arabidopsis leaves, NIA2, but negative regulators of the nitrate uptake gene NRT1.1, Journal of Plant Physiology, 166, 2071, 10.1016/j.jplph.2009.05.010 · doi:10.1016/j.jplph.2009.05.010
  24. 2016, Plant nitrogen acquisition under low availability: regulation of uptake and root architecture, Plant & Cell Physiology, 57, 707, 10.1093/pcp/pcw052 · doi:10.1093/pcp/pcw052
  25. 1999, Molecular and functional regulation of two NO3− uptake systems by N- and C-status of Arabidopsis plants, The Plant Journal, 18, 509, 10.1046/j.1365-313X.1999.00480.x · doi:10.1046/j.1365-313x.1999.00480.x
  26. 2015, AtNPF5.5, a nitrate transporter affecting nitrogen accumulation in Arabidopsis embryo, Scientific Reports, 5, 7962, 10.1038/srep07962 · doi:10.1038/srep07962
  27. 2011, Coordinated transcriptional regulation underlying the circadian clock in Arabidopsis, Nature Cell Biology, 13, 616, 10.1038/ncb2219 · doi:10.1038/ncb2219
  28. 2015, Disruption of the rice nitrate transporter OsNPF2.2 hinders root-to-shoot nitrate transport and vascular development, Scientific Reports, 5, 9635, 10.1038/srep09635 · doi:10.1038/srep09635
  29. 2000, Cloning and functional characterization of a constitutively expressed nitrate transporter gene, OsNRT1, from rice, Plant Physiology, 122, 379, 10.1104/pp.122.2.379 · doi:10.1104/pp.122.2.379
  30. 2014, Identification and functional assay of the interaction motifs in the partner protein OsNAR2.1 of the two-component system for high-affinity nitrate transport, The New Phytologist, 204, 74, 10.1111/nph.12986 · doi:10.1111/nph.12986
  31. 2016, NAR2.1/NRT2.1 functional interaction with NO3– and H+ fluxes in high-affinity nitrate transport in maize root regions, Plant Physiology and Biochemistry, 102, 107, 10.1016/j.plaphy.2016.02.022 · doi:10.1016/j.plaphy.2016.02.022
  32. 2014, A single-pore residue renders the Arabidopsis root anion channel SLAH2 highly nitrate selective, The Plant Cell, 26, 2554, 10.1105/tpc.114.125849 · doi:10.1105/tpc.114.125849
  33. 2009, The Arabidopsis abscisic acid catabolic gene CYP707A2 plays a key role in nitrate control of seed dormancy, Plant Physiology, 149, 949, 10.1104/pp.108.126938 · doi:10.1104/pp.108.126938
  34. 2014, The primary nitrate response: a multifaceted signalling pathway, Journal of Experimental Botany, 65, 5567, 10.1093/jxb/eru245 · doi:10.1093/jxb/eru245
  35. 2011, Characterization of a dual-affinity nitrate transporter MtNRT1.3 in the model legume Medicago truncatula, Journal of Experimental Botany, 62, 5595, 10.1093/jxb/err243 · doi:10.1093/jxb/err243
  36. 2014, Auxin-mediated nitrate signalling by NRT1.1 participates in the adaptive response of Arabidopsis root architecture to the spatial heterogeneity of nitrate availability, Plant, Cell & Environment, 37, 162, 10.1111/pce.12143 · doi:10.1111/pce.12143
  37. 2009, Two anion transporters AtClCa and AtClCe fulfil interconnecting but not redundant roles in nitrate assimilation pathways, The New Phytologist, 183, 88, 10.1111/j.1469-8137.2009.02837.x · doi:10.1111/j.1469-8137.2009.02837.x
  38. 2014, Members of the NPF3 transporter subfamily encode pathogen-inducible nitrate/nitrite transporters in grapevine and Arabidopsis, Plant & Cell Physiology, 55, 162, 10.1093/pcp/pct167 · doi:10.1093/pcp/pct167
  39. 2006, A central role for the nitrate transporter NRT2.1 in the integrated morphological and physiological responses of the root system to nitrogen limitation in Arabidopsis, Plant Physiology, 140, 909, 10.1104/pp.105.075721 · doi:10.1104/pp.105.075721
  40. 2007, Nitrate efflux at the root plasma membrane: identification of an Arabidopsis excretion transporter, The Plant Cell, 19, 3760, 10.1105/tpc.106.048173 · doi:10.1105/tpc.106.048173
  41. 2015, Post-flowering nitrate uptake in wheat is controlled by N status at flowering, with a putative major role of root nitrate transporter NRT2.1, PLoS One, 10, e0120291, 10.1371/journal.pone.0120291 · doi:10.1371/journal.pone.0120291
  42. 2013, ZmPTR1, a maize peptide transporter expressed in the epithelial cells of the scutellum during germination, Plant Science, 207, 140, 10.1016/j.plantsci.2013.03.005 · doi:10.1016/j.plantsci.2013.03.005
  43. 2011, Rice OsNAR2.1 interacts with OsNRT2.1, OsNRT2.2 and OsNRT2.3a nitrate transporters to provide uptake over high and low concentration ranges, Plant, Cell & Environment, 34, 1360, 10.1111/j.1365-3040.2011.02335.x · doi:10.1111/j.1365-3040.2011.02335.x
  44. 2012, Leaching of nitrogen from calcareous soils in western Iran: a soil leaching column study, Environmental Monitoring and Assessment, 184, 7607, 10.1007/s10661-012-2522-3 · doi:10.1007/s10661-012-2522-3
  45. 2016, The Arabidopsis nitrate transporter NPF7.3/NRT1.5 is involved in lateral root development under potassium deprivation, Plant Signaling & Behavior, 11, e1176819, 10.1080/15592324.2016.1176819 · doi:10.1080/15592324.2016.1176819
  46. 1998, Cloning and functional characterization of a Brassica napus transporter that is able to transport nitrate and histidine, The Journal of Biological Chemistry, 273, 12017, 10.1074/jbc.273.20.12017 · doi:10.1074/jbc.273.20.12017

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Metadata

Authors
Fan, X., Naz, M., Fan, X., Xuan, W., Miller, A. J., & Xu, G.
Venue
Journal of Experimental Botany
Publisher
Oxford University Press (OUP)
Published
2017-02-03
Volume
68
Issue
10
Pages
2463-2475
ISSN
  • 0022-0957 (ISSN-L)
  • 1460-2431
DOI
10.1093/jxb/erx011
OpenAlex
W2585826463
Cited by
365
References
101
FWCI
24.17
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Plant nitrate transporters: from gene function to application. https://app.cochat.ai/papers/10.1093/jxb/erx011
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Fan, X., Naz, M., Fan, X., Xuan, W., Miller, A. J., & Xu, G. (2017). Plant nitrate transporters: from gene function to application. Journal of Experimental Botany. https://doi.org/10.1093/jxb/erx011

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