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The Unified Protocol for Transdiagnostic Treatment of Emotional Disorders: An Introduction
Abstract
This chapter recounts the origins of the Unified Protocol for Transdiagnostic Treatment of Emotional Disorders (UP) as it developed over a period of several decades. The rationale for developing it was derived from research emerging over this period of time that highlighted commonalities among anxiety, depressive, and related disorders, focusing on emotional disruption and dysregulation, as well as research highlighting common underlying temperamental factors associated with all these disorders. With a particular emphasis on the temperament of neuroticism, transdiagnostic constructs in emotional disorders that are fundamental aspects of neuroticism, such as increased anxiety sensitivity, decreased mindfulness, experiential avoidance, and negative appraisals and attributions, were identified and became targets for treatment. After presentation of the core elements comprising the UP, research supporting its efficacy, including a recently completed large clinical trial, is presented.
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“or they are uncontrolled trials [50-52].”
From Negative and positive affect regulation in a transdiagnostic internet-based protocol for emotional disorders: Randomized controlled trial (2021) · cites this paper as [51]
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Winhusen, T. M., Walley, A. Y., Fanucchi, L. C., Hunt, T., Lyons, M., Lofwall, M. R., Brown, J. L., Freeman, P. R., Nunes, E. V., Beers, D., et al. (2020) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2020.108325 · Cited by 135
Wright, A. G. C., Pincus, A. L., & Hopwood, C. J. (2023) · Journal of Psychopathology and Clinical Science · doi:10.1037/abn0000741 · Cited by 105
Lungu, A., Jun, J. J., Azarmanesh, O., Leykin, Y., & Chen, C. E.-J. (2020) · Journal of Medical Internet Research · doi:10.2196/18723 · Cited by 75
Southward, M. W., Sauer-Zavala, S. E., & Cheavens, J. S. (2021) · Clinical Psychology Science and Practice · doi:10.1037/cps0000003 · Cited by 69
Díaz-García, A., González-Robles, A., García-Palacios, A., Fernández-Álvarez, J., Castilla, D., Bretón, J. M., Baños, R. M., Quero, S., & Botella, C. (2021) · Journal of Medical Internet Research · doi:10.2196/21335 · Cited by 36
Metadata
- Authors
- Kennedy, K. A., & Barlow, D. H.
- ORCID
- Barlow, David H.
- Venue
- Applications of the Unified Protocol for Transdiagnostic Treatment of Emotional Disorders
- Publisher
- Oxford University Press
- Published
- 2017-08
- Pages
- 1-16
- OpenAlex
- W4243572921
- Cited by
- 46
- References
- 0
- Citations by year
- 2026: 2 · 2025: 1 · 2024: 7 · 2023: 13 · 2022: 8 · 2021: 5 · 2020: 7 · 2018: 3
- FWCI
- 11.29
- Type
- book chapter
- Language
- en
- Open access
- closed
- Locations
- Oxford University Press eBooks (publishedVersion)
- Topics
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Social Sciences › Psychology › Clinical Psychology › Personality Disorders and Psychopathology
- Social Sciences › Psychology › Clinical Psychology › Psychotherapy Techniques and Applications
- Keywords
- Unified Protocol for Transdiagnostic Treatment of Emotional Disorders, transdiagnostic treatment, emotional disorders, anxiety disorders, depression, emotional dysregulation, neuroticism, anxiety sensitivity, mindfulness, experiential avoidance, treatment efficacy
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