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Human Papillomavirus Infection of the Cervix: Relative Risk Association of 15 Common Anogenital Types
Abstract
In 1992 Lorincz et al. were the first to evaluate the clinicopathologic correlation with 11 recently identified human papillomavirus (HPV) genotypes: 31, 33, 35, 42, 43, 44, 45, 51, 52, 56, and 58. Using cervical samples from 8 studies that included specimens from 2627 women, HPV genotypes were categorized by the likelihood of association with grades of cervical neoplasia (from normal to cancer). These findings were the basis of the determination that (a) HPV causes cervical cancer, (b) detection of the cancer associated HPV genotypes could identify women at risk for cervical pre-cancer and cancer, and (c) a prophylactic HPV vaccine should include protection against (at least) HPV 16 and 18.
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Citations
Cited by
Human papillomavirus and cervical cancer
Burd, E. M. (2003) · Clinical Microbiology Reviews · doi:10.1128/cmr.16.1.1-17.2003 · Cited by 2,420
Epidemiology of Genital Human Papillomavirus Infection
Koutsky, P. (1997) · The American Journal of Medicine · doi:10.1016/s0002-9343(97)00177-0 · Cited by 1,107
Molecular biology of human papillomavirus infection and cervical cancer
Doorbar, J. (2006) · Clinical Science · doi:10.1042/cs20050369 · Cited by 1,072
The epidemiology of genital human papillomavirus infection
Trottier, H., & Franco, E. L. (2006) · Vaccine · doi:10.1016/j.vaccine.2005.09.054 · Cited by 686
Clifford, G. M., Smith, J. S., Aguado, T., & Franceschi, S. (2003) · British Journal of Cancer · doi:10.1038/sj.bjc.6601024 · Cited by 684
Metadata
- Authors
- Mills, J. M., & Stier, E. A.
- Venue
- 50 Studies Every Obstetrician-Gynecologist Should Know
- Publisher
- Oxford University Press
- Published
- 2021-01
- Pages
- 170-174
- OpenAlex
- W3128343078
- Cited by
- 756
- References
- 0
- FWCI
- 7.31
- Type
- book chapter
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Human Papillomavirus Infection of the Cervix: Relative Risk Association of 15 Common Anogenital Types. https://app.cochat.ai/papers/10.1093/med/9780190947088.003.0031
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- Mills, J. M., & Stier, E. A. (2021). Human Papillomavirus Infection of the Cervix: Relative Risk Association of 15 Common Anogenital Types. 50 Studies Every Obstetrician-Gynecologist Should Know. https://doi.org/10.1093/med/9780190947088.003.0031
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