The DOI matches its Crossref record; 55 of the 55 references it cites were found in a registry or an index.
What Is the Role of Genome Duplication in the Evolution of Complexity and Diversity?
Abstract
Gene and genome duplications provide a source of genetic material for mutation, drift, and selection to act upon, making new evolutionary opportunities possible. As a result, many have argued that genome duplication is a dominant factor in the evolution of complexity and diversity. However, a clear correlation between a genome duplication event and increased complexity and diversity is not apparent, and there are inconsistencies in the patterns of diversity invoked to support this claim. Interestingly, several estimates of genome duplication events in vertebrates are preceded by multiple extinct lineages, resulting in preduplication gaps in extant taxa. Here we argue that gen(om)e duplication could contribute to reduced risk of extinction via functional redundancy, mutational robustness, increased rates of evolution, and adaptation. The timeline for these processes to unfold would not predict immediate increases in species diversity after the duplication event. Rather, reduced probabilities of extinction would predict a latent period between a genome duplication and its effect on species diversity or complexity. In this paper, we will develop the idea that genome duplication could contribute to species diversity through reduced probability of extinction.
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Cites
Ohno, S. (1970) · doi:10.1007/978-3-642-86659-3 · Cited by 7,833
The Evolutionary Fate and Consequences of Duplicate Genes
Lynch, M., & Conery, J. S. (2000) · Science · doi:10.1126/science.290.5494.1151 · Cited by 4,988
Preservation of Duplicate Genes by Complementary, Degenerative Mutations
Force, A., Lynch, M., Pickett, F. B., Amores, A., Yan, Y.-L., & Postlethwait, J. (1999) · Genetics · doi:10.1093/genetics/151.4.1531 · Cited by 3,529
Polyploid incidence and evolution
Otto, S. P., & Whitton, J. (2000) · Annual Review of Genetics · doi:10.1146/annurev.genet.34.1.401 · Cited by 2,363
Evolution by gene duplication: An update
Zhang, J. (2003) · Trends in Ecology & Evolution · doi:10.1016/s0169-5347(03)00033-8 · Cited by 2,201
Genome evolution in polyploids
Wendel, J. F. (2000) · Plant Molecular Biology · doi:10.1023/a:1006392424384 · Cited by 1,600
Unravelling angiosperm genome evolution by phylogenetic analysis of chromosomal duplication events
Bowers, J. E., Chapman, B. A., Rong, J., & Paterson, A. H. (2003) · Nature · doi:10.1038/nature01521 · Cited by 1,599
Proof and evolutionary analysis of ancient genome duplication in the yeast Saccharomyces cerevisiae
Kellis, M., Birren, B. W., & Lander, E. S. (2004) · Nature · doi:10.1038/nature02424 · Cited by 1,522
Blanc, G., & Wolfe, K. H. (2004) · The Plant Cell · doi:10.1105/tpc.021345 · Cited by 1,233
Polyploidy: recurrent formation and genome evolution
Soltis, D. E., & Soltis, P. S. (1999) · Trends in Ecology & Evolution · doi:10.1016/s0169-5347(99)01638-9 · Cited by 1,109
Cited by
The evolutionary significance of ancient genome duplications
Van de Peer, Y., Maere, S., & Meyer, A. (2009) · Nature Reviews Genetics · doi:10.1038/nrg2600 · Cited by 1,129
Freeling, M. (2009) · Annual Review of Plant Biology · doi:10.1146/annurev.arplant.043008.092122 · Cited by 1,015
Polyploidy: an evolutionary and ecological force in stressful times
Van de Peer, Y., Ashman, T.-L., Soltis, P. S., & Soltis, D. E. (2021) · The Plant Cell · doi:10.1093/plcell/koaa015 · Cited by 732
Genome sequence and genetic diversity of the common carp, Cyprinus carpio
Xu, P., Zhang, X., Wang, X., Li, J., Liu, G., Kuang, Y., Xu, J., Zheng, X., Ren, L., Wang, G., et al. (2014) · Nature Genetics · doi:10.1038/ng.3098 · Cited by 658
Santini, F., Harmon, L. J., Carnevale, G., & Alfaro, M. E. (2009) · BMC Evolutionary Biology · doi:10.1186/1471-2148-9-194 · Cited by 317
Metadata
- Authors
- Crow, K. D.
- Venue
- Molecular Biology and Evolution
- Publisher
- Oxford University Press (OUP)
- Published
- 2006-02-22
- Volume
- 23
- Issue
- 5
- Pages
- 887-892
- ISSN
- 0737-4038 (ISSN-L)
- 1537-1719
- OpenAlex
- W2010407417
- Cited by
- 277
- References
- 55
- FWCI
- 6.88
- Type
- journal article
- Language
- en
- Open access
- closed
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
