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Origin of Primate Orphan Genes: A Comparative Genomics Approach
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New genes tend to be shorter, evolve faster, and have lower expression than well-established genes.
“Given that new genes tend to be shorter, evolve faster, and have lower expression than well-established genes (Toll-Riera et al. 2009, Zhao et al. 2024), some of the surplus short genes inferred in ab initio could potentially be true lineage-specific genes.”
From Annotation matters: the effect of structural gene annotation on orthology inference (2025) · cites this paper as Toll-Riera et al. 2009
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Self-citationA Human-Specific De Novo Protein-Coding Gene Associated with Human Brain Functions
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Annotation matters: the effect of structural gene annotation on orthology inference
Prieto-Baños, S., Nevers, Y., Altenhoff, A., Warwick Vesztrocy, A., Dessimoz, C., & Glover, N. M. (2025) · Bioinformatics · doi:10.1093/bioinformatics/btaf365 · Cited by 19
Metadata
- Authors
- Toll-Riera, M., Bosch, N., Bellora, N., Castelo, R., Armengol, L., Estivill, X., & Mar Alba, M.
- Venue
- Molecular Biology and Evolution
- Publisher
- Oxford University Press (OUP)
- Published
- 2008-12-23
- Volume
- 26
- Issue
- 3
- Pages
- 603-612
- ISSN
- 0737-4038
- 1537-1719
- Cited by
- 218
- References
- 4
- Language
- en
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