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Compilation and analysis of Escherichia coli promoter DNA sequences

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Hawley, Diane K., McClure, William R.·1983·Nucleic Acids Research

Abstract

The DNA sequence of 168 promoter regions (-50 to +10) for Escherichia coli RNA polymerase were compiled. The complete listing was divided into two groups depending upon whether or not the promoter had been defined by genetic (promoter mutations) or biochemical (5' end determination) criteria. A consensus promoter sequence based on homologies among 112 well-defined promoters was determined that was in substantial agreement with previous compilations. In addition, we have tabulated 98 promoter mutations. Nearly all of the altered base pairs in the mutants conform to the following general rule: down-mutations decrease homology and up-mutations increase homology to the consensus sequence.

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Metadata

Authors
Hawley, D. K., & McClure, W. R.
Venue
Nucleic Acids Research
Published
1983
Volume
11
Issue
8
Pages
2237-2255
ISSN
  • 0305-1048 (ISSN-L)
  • 1362-4962
OpenAlex
W2071424950
Cited by
2,204
References
0
FWCI
103.47
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Compilation and analysis of Escherichia coli promoter DNA sequences. https://app.cochat.ai/papers/10.1093/nar/11.8.2237
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Hawley, D. K., & McClure, W. R. (1983). Compilation and analysis of Escherichia coli promoter DNA sequences. Nucleic Acids Research. https://doi.org/10.1093/nar/11.8.2237

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