The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Hypervariability of simple sequences as a general source for polymorphic DNA markers
Open accessAbstract
Short simple sequence stretches occur as highly repetitive elements in all eukaryotic genomes and partially also in prokaryotes and eubacteria. They are thought to arise by slippage like events working on randomly occurring internally repetitive sequence stretches. This predicts that they should be generally hypervariable in length. I have used the polymerase chain reaction (PCR) process to show that several randomly chosen simple sequence loci with different nucleotide composition and from different species show extensive length polymorphisms. These simple sequence length polymorphisms (SSLP) may be usefully exploited for identity testing, population studies, linkage analysis and genome mapping.
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Cites
Primer-Directed Enzymatic Amplification of DNA with a Thermostable DNA Polymerase
Saiki, R. K., Gelfand, D. H., Stoffel, S., Scharf, S. J., Higuchi, R., Horn, G. T., Mullis, K. B., & Erlich, H. A. (1988) · Science · doi:10.1126/science.2448875 · Cited by 17,719
Frameshift Mutations and the Genetic Code
Streisinger, G., Okada, Y., Emrich, J., Newton, J., Tsugita, A., Terzaghi, E., & Inouye, M. (1966) · Cold Spring Harbor Symposia on Quantitative Biology · doi:10.1101/sqb.1966.031.01.014 · Cited by 1,400
Cited by
Kirschner, L. S., Carney, J. A., Pack, S. D., Taymans, S. E., Giatzakis, C., Cho, Y. S., Cho-Chung, Y. S., & Stratakis, C. A. (2000) · Nature Genetics · doi:10.1038/79238 · Cited by 1,153
Hellborg, L., & Ellegren, H. (2003) · Molecular Ecology · doi:10.1046/j.1365-294x.2003.01702.x · Cited by 788
Waugh, R., McLean, K., Flavell, A. J., Pearce, S. R., Kumar, A., Thomas, B. B. T., & Powell, W. (1997) · Molecular and General Genetics MGG · doi:10.1007/s004380050372 · Cited by 466
Contributions of PCR-Based Methods to Plant Systematics and Evolutionary Biology
Wolfe, A. D., & Liston, A. (1998) · Molecular Systematics of Plants II · doi:10.1007/978-1-4615-5419-6_2 · Cited by 411
Genetic tagging of humpback whales
Palsbøll, P. J., Allen, J., Bérube´, M., Clapham, P. J., Feddersen, T. P., Hammond, P. S., Hudson, R. R., Jørgensen, H., Katona, S., Larsen, A. H., et al. (1997) · Nature · doi:10.1038/42005 · Cited by 377
Metadata
- Authors
- Tautz, D.
- Venue
- Nucleic Acids Research
- Publisher
- Oxford University Press (OUP)
- Published
- 1989-08-25
- Volume
- 17
- Issue
- 16
- Pages
- 6463-6471
- ISSN
- 0305-1048 (ISSN-L)
- 1362-4962
- OpenAlex
- W2156843275
- Cited by
- 2,315
- References
- 2
- FWCI
- 64.72
- Type
- journal article
- Language
- en
- Open access
- bronze
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