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Cited by 13,067

The DOI matches its Crossref record.

DNA polymorphisms amplified by arbitrary primers are useful as genetic markers

Open access
Williams, John G.K., Kubelik, Anne R., Livak, Kenneth J., Rafalski, J.Antoni, Tingey, Scott V.·1990·Nucleic Acids Research
DOI 10.1093/nar/18.22.6531
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Abstract

Molecular genetic maps are commonly constructed by analyzing the segregation of restriction fragment length polymorphisms (RFLPs) among the progeny of a sexual cross. Here we describe a new DNA polymorphism assay based on the amplification of random DNA segments with single primers of arbitrary nucleotide sequence. These polymorphisms, simply detected as DNA segments which amplify from one parent but not the other, are inherited in a Mendelian fashion and can be used to construct genetic maps in a variety of species. We suggest that these polymorphisms be called RAPD markers, after Random Amplified Polymorphic DNA.

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Metadata

Authors
Williams, J. G. K., Kubelik, A. R., Livak, K. J., Rafalski, J. A., & Tingey, S. V.
Venue
Nucleic Acids Research
Publisher
Oxford University Press (OUP)
Published
1990
Volume
18
Issue
22
Pages
6531-6535
ISSN
  • 0305-1048 (ISSN-L)
  • 1362-4962
DOI
10.1093/nar/18.22.6531
OpenAlex
W2171114940
Cited by
13,067
References
0
FWCI
122.87
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: DNA polymorphisms amplified by arbitrary primers are useful as genetic markers. https://app.cochat.ai/papers/10.1093/nar/18.22.6531
The paper
Williams, J. G. K., Kubelik, A. R., Livak, K. J., Rafalski, J. A., & Tingey, S. V. (1990). DNA polymorphisms amplified by arbitrary primers are useful as genetic markers. Nucleic Acids Research. https://doi.org/10.1093/nar/18.22.6531

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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