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Pfam 3.1: 1313 multiple alignments and profile HMMs match the majority of proteins
Open accessAbstract
Pfam is a collection of multiple alignments and profile hidden Markov models of protein domain families. Release 3.1 is a major update of the Pfam database and contains 1313 families which are available on the World Wide Web in Europe at http://www.sanger.ac.uk/Software/Pfam/ and http://www.cgr.ki.se/Pfam/, and in the US at http://pfam.wustl.edu/. Over 54% of proteins in SWISS-PROT-35 and SP-TrEMBL-5 match a Pfam family. The primary changes of Pfam since release 2.1 are that we now use the more advanced version 2 of the HMMER software, which is more sensitive and provides expectation values for matches, and that it now includes proteins from both SP-TrEMBL and SWISS-PROT.
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Metadata
- Authors
- Bateman, A., Birney, E., Durbin, R., Eddy, S. R., Finn, R. D., & Sonnhammer, E. L. L.
- Venue
- Nucleic Acids Research
- Publisher
- Oxford University Press (OUP)
- Published
- 1999-01-01
- Volume
- 27
- Issue
- 1
- Pages
- 260-262
- ISSN
- 0305-1048 (ISSN-L)
- 1362-4962
- OpenAlex
- W2100018338
- Cited by
- 507
- References
- 0
- FWCI
- 28.71
- Type
- journal article
- Language
- en
- Open access
- green
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- Bateman, A., Birney, E., Durbin, R., Eddy, S. R., Finn, R. D., & Sonnhammer, E. L. L. (1999). Pfam 3.1: 1313 multiple alignments and profile HMMs match the majority of proteins. Nucleic Acids Research. https://doi.org/10.1093/nar/27.1.260
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