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The genome sequence of Bacillus cereus ATCC 10987 reveals metabolic adaptations and a large plasmid related to Bacillus anthracis pXO1

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Rasko, D. A.·2004·Nucleic Acids Research

Abstract

We sequenced the complete genome of Bacillus cereus ATCC 10987, a non-lethal dairy isolate in the same genetic subgroup as Bacillus anthracis. Comparison of the chromosomes demonstrated that B.cereus ATCC 10987 was more similar to B.anthracis Ames than B.cereus ATCC 14579, while containing a number of unique metabolic capabilities such as urease and xylose utilization and lacking the ability to utilize nitrate and nitrite. Additionally, genetic mechanisms for variation of capsule carbohydrate and flagella surface structures were identified. Bacillus cereus ATCC 10987 contains a single large plasmid (pBc10987), of approximately 208 kb, that is similar in gene content and organization to B.anthracis pXO1 but is lacking the pathogenicity-associated island containing the anthrax lethal and edema toxin complex genes. The chromosomal similarity of B.cereus ATCC 10987 to B.anthracis Ames, as well as the fact that it contains a large pXO1-like plasmid, may make it a possible model for studying B.anthracis plasmid biology and regulatory cross-talk.

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Metadata

Authors
Rasko, D. A.
Venue
Nucleic Acids Research
Published
2004-02-13
Volume
32
Issue
3
Pages
977-988
ISSN
  • 0305-1048 (ISSN-L)
  • 1362-4962
OpenAlex
W2121297340
Cited by
312
References
2
FWCI
14.10
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: The genome sequence of Bacillus cereus ATCC 10987 reveals metabolic adaptations and a large plasmid related to Bacillus anthracis pXO1. https://app.cochat.ai/papers/10.1093/nar/gkh258
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Rasko, D. A. (2004). The genome sequence of Bacillus cereus ATCC 10987 reveals metabolic adaptations and a large plasmid related to Bacillus anthracis pXO1. Nucleic Acids Research. https://doi.org/10.1093/nar/gkh258

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