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TCDB: the Transporter Classification Database for membrane transport protein analyses and information

Open access
Saier, M. H.·2006·Nucleic Acids Research

Abstract

The Transporter Classification Database (TCDB) is a web accessible, curated, relational database containing sequence, classification, structural, functional and evolutionary information about transport systems from a variety of living organisms. TCDB is a curated repository for factual information compiled from >10,000 references, encompassing approximately 3000 representative transporters and putative transporters, classified into >400 families. The transporter classification (TC) system is an International Union of Biochemistry and Molecular Biology approved system of nomenclature for transport protein classification. TCDB is freely accessible at http://www.tcdb.org. The web interface provides several different methods for accessing the data, including step-by-step access to hierarchical classification, direct search by sequence or TC number and full-text searching. The functional ontology that underlies the database structure facilitates powerful query searches that yield valuable data in a quick and easy way. The TCDB website also offers several tools specifically designed for analyzing the unique characteristics of transport proteins. TCDB not only provides curated information and a tool for classifying newly identified membrane proteins, but also serves as a genome transporter-annotation tool.

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Metadata

Authors
Saier, M. H.
Venue
Nucleic Acids Research
Published
2006-01-01
Volume
34
Issue
90001
Pages
D181-D186
ISSN
  • 0305-1048 (ISSN-L)
  • 1362-4962
OpenAlex
W2144944670
Cited by
858
References
2
FWCI
12.30
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: TCDB: the Transporter Classification Database for membrane transport protein analyses and information. https://app.cochat.ai/papers/10.1093/nar/gkj001
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Saier, M. H. (2006). TCDB: the Transporter Classification Database for membrane transport protein analyses and information. Nucleic Acids Research. https://doi.org/10.1093/nar/gkj001

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