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Cited by 1,522

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NCBI GEO: mining tens of millions of expression profiles--database and tools update

Open access
Barrett, T., Troup, D. B., Wilhite, S. E., Ledoux, P., Rudnev, D., Evangelista, C., Kim, I. F., Soboleva, A., Tomashevsky, M., Edgar, R.·2007·Nucleic Acids Research

Abstract

The Gene Expression Omnibus (GEO) repository at the National Center for Biotechnology Information (NCBI) archives and freely disseminates microarray and other forms of high-throughput data generated by the scientific community. The database has a minimum information about a microarray experiment (MIAME)-compliant infrastructure that captures fully annotated raw and processed data. Several data deposit options and formats are supported, including web forms, spreadsheets, XML and Simple Omnibus Format in Text (SOFT). In addition to data storage, a collection of user-friendly web-based interfaces and applications are available to help users effectively explore, visualize and download the thousands of experiments and tens of millions of gene expression patterns stored in GEO. This paper provides a summary of the GEO database structure and user facilities, and describes recent enhancements to database design, performance, submission format options, data query and retrieval utilities. GEO is accessible at http://www.ncbi.nlm.nih.gov/geo/

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Metadata

Authors
Barrett, T., Troup, D. B., Wilhite, S. E., Ledoux, P., Rudnev, D., Evangelista, C., Kim, I. F., Soboleva, A., Tomashevsky, M., & Edgar, R.
Venue
Nucleic Acids Research
Published
2007-01-03
Volume
35
Issue
Database
Pages
D760-D765
ISSN
  • 0305-1048 (ISSN-L)
  • 1362-4962
OpenAlex
W2154362705
Cited by
1,522
References
1
FWCI
51.45
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: NCBI GEO: mining tens of millions of expression profiles--database and tools update. https://app.cochat.ai/papers/10.1093/nar/gkl887
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Barrett, T., Troup, D. B., Wilhite, S. E., Ledoux, P., Rudnev, D., Evangelista, C., Kim, I. F., Soboleva, A., Tomashevsky, M., & Edgar, R. (2007). NCBI GEO: mining tens of millions of expression profiles--database and tools update. Nucleic Acids Research. https://doi.org/10.1093/nar/gkl887

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