Cited by 13,288Gene expression and cancer classificationBioinformatics and Genomic NetworksGenomics and Phylogenetic Studies

Gene Expression Omnibus: NCBI gene expression and hybridization array data repository

Open access
Edgar, R.·2002·Nucleic Acids Research

Abstract

The Gene Expression Omnibus (GEO) project was initiated in response to the growing demand for a public repository for high-throughput gene expression data. GEO provides a flexible and open design that facilitates submission, storage and retrieval of heterogeneous data sets from high-throughput gene expression and genomic hybridization experiments. GEO is not intended to replace in house gene expression databases that benefit from coherent data sets, and which are constructed to facilitate a particular analytic method, but rather complement these by acting as a tertiary, central data distribution hub. The three central data entities of GEO are platforms, samples and series, and were designed with gene expression and genomic hybridization experiments in mind. A platform is, essentially, a list of probes that define what set of molecules may be detected. A sample describes the set of molecules that are being probed and references a single platform used to generate its molecular abundance data. A series organizes samples into the meaningful data sets which make up an experiment. The GEO repository is publicly accessible through the World Wide Web at http://www.ncbi.nlm.nih.gov/geo.

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Registry

Crossref · 10.1093/nar/30.1.207

Cites

7 of 7 references verified0 citation errors · 0 not checkable

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Authors
Edgar, R.
Affiliations
National Institutes of Health (US)
Corresponding author
Edgar, R.
Venue
Nucleic Acids Research
Published
2002-01-01
Volume
30
Issue
1
Pages
207-210
ISSN
  • 0305-1048 (ISSN-L)
  • 1362-4962
OpenAlex
W2020541351
Cited by
13,288
References
8
Citations by year
2026: 616 · 2025: 746 · 2024: 960 · 2023: 1010 · 2022: 991 · 2021: 1102 · 2020: 991 · 2019: 820 · 2018: 689 · 2017: 668 · 2016: 658 · 2015: 649 · 2014: 638 · 2013: 570 · 2012: 510
FWCI
27.23
Type
journal article
Language
en
Open access
Locations
  • Nucleic Acids Research (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gene expression and cancer classification
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Bioinformatics and Genomic Networks
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Genomics and Phylogenetic Studies
Keywords
Gene Expression Omnibus, gene expression data, genomic hybridization, microarray data, public data repositories, data submission, data storage and retrieval, biological specimen
MeSH terms
Animals, Communication, Database Management Systems, Forecasting, Humans, National Library of Medicine (U.S.), United States, Information Storage and Retrieval, Genome, Internet, Oligonucleotide Array Sequence Analysis, Gene Expression Profiling, Databases, Genetic

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