The DOI matches its Crossref record; 48 of the 48 references it cites were found in a registry or an index.
Transgenerational changes in the genome stability and methylation in pathogen-infected plants
Open accessAbstract
Previously, we reported the generation of a virus-induced systemic signal that increased the somatic and meiotic recombination rates in tobacco mosaic virus (TMV)-infected tobacco plants. Here, we analyzed the progeny of plants that received the signal and found that these plants also have a higher frequency of rearrangements in the loci carrying the homology to LRR region of the gene of resistance to TMV (N-gene). Analysis of the stability of repetitive elements from Nicotiana tabacum loci and 5.8S ribosomal RNA loci did not show any changes. Further analysis of the changes in the progeny of infected plants revealed that they had substantially hypermethylated genomes. At the same time, loci-specific methylation analysis showed: (1) profound hypomethylation in several LRR-containing loci; (2) substantial hypermethylation of actin loci and (3) no change in methylation in the loci of repetitive elements from N. tabacum or 5.8S ribosomal RNA. Global genome hypermethylation of the progeny is believed to be part of a general protection mechanism against stress, whereas locus-specific hypomethylation is associated with a higher frequency of rearrangements. Increased recombination events combined with the specific methylation pattern induced by pathogen attack could be a sign of an adaptive response by plants.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Epigenetic programming by maternal behavior
Weaver, I. C. G., Cervoni, N., Champagne, F. A., D'Alessio, A. C., Sharma, S., Seckl, J. R., Dymov, S., Szyf, M., & Meaney, M. J. (2004) · Nature Neuroscience · doi:10.1038/nn1276 · Cited by 6,177
Frommer, M., McDonald, L. E., Millar, D. S., Collis, C. M., Watt, F., Grigg, G. W., Molloy, P. L., & Paul, C. L. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.5.1827 · Cited by 3,238
Regulatory network of gene expression in the drought and cold stress responses
Shinozaki, K., Yamaguchi-Shinozaki, K., & Seki, M. (2003) · Current Opinion in Plant Biology · doi:10.1016/s1369-5266(03)00092-x · Cited by 1,787
Whitham, S., Dinesh-Kumar, S. P., Choi, D., Hehl, R., Corr, C., & Baker, B. (1994) · Cell · doi:10.1016/0092-8674(94)90283-6 · Cited by 1,346
COBRA: a sensitive and quantitative DNA methylation assay
Xiong, Z., & Laird, P. W. (1997) · Nucleic Acids Research · doi:10.1093/nar/25.12.2532 · Cited by 1,195
Direct interaction of resistance gene and avirulence gene products confers rice blast resistance
Jia, Y., McAdams, S. A., Bryan, G. T., Hershey, H. P., & Valent, B. (2000) · The EMBO Journal · doi:10.1093/emboj/19.15.4004 · Cited by 1,151
Molecular genetic perspectives on cross-talk and specificity in abiotic stress signalling in plants
Chinnusamy, V. (2003) · Journal of Experimental Botany · doi:10.1093/jxb/erh005 · Cited by 1,127
A Polypeptide from Tomato Leaves Induces Wound-Inducible Proteinase Inhibitor Proteins
Pearce, G., Strydom, D., Johnson, S., & Ryan, C. A. (1991) · Science · doi:10.1126/science.253.5022.895 · Cited by 1,079
Signal Signature and Transcriptome Changes of Arabidopsis During Pathogen and Insect Attack
De Vos, M., Van Oosten, V. R., Van Poecke, R. M. P., Van Pelt, J. A., Pozo, M. J., Mueller, M. J., Buchala, A. J., Métraux, J.-P., Van Loon, L. C., Dicke, M., et al. (2005) · Molecular Plant-Microbe Interactions® · doi:10.1094/mpmi-18-0923 · Cited by 974
The Mechanism and Regulation of Chromosomal V(D)J Recombination
Bassing, C. H., Swat, W., & Alt, F. W. (2002) · Cell · doi:10.1016/s0092-8674(02)00675-x · Cited by 967
Cited by
Epigenetic regulation of stress responses in plants
Chinnusamy, V., & Zhu, J.-K. (2009) · Current Opinion in Plant Biology · doi:10.1016/j.pbi.2008.12.006 · Cited by 1,162
Babenko, O., Kovalchuk, I., & Metz, G. A. S. (2015) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2014.11.013 · Cited by 513
Self-citationBoyko, A., Blevins, T., Yao, Y., Golubov, A., Bilichak, A., Ilnytskyy, Y., Hollander, J., Meins, F., & Kovalchuk, I. (2010) · Zurich Open Repository and Archive (University of Zurich) · doi:10.5167/uzh-44099 · Cited by 462
Self-citationImpact of transposable elements on the organization and function of allopolyploid genomes
Parisod, C., Alix, K., Just, J., Petit, M., Sarilar, V., Mhiri, C., Ainouche, M., Chalhoub, B., & Grandbastien, M. (2010) · New Phytologist · doi:10.1111/j.1469-8137.2009.03096.x · Cited by 265
Smith, O., Clapham, A. J., Rose, P., Liu, Y., Wang, J., & Allaby, R. G. (2014) · Scientific Reports · doi:10.1038/srep05559 · Cited by 59
Metadata
- Authors
- Boyko, A., Kathiria, P., Zemp, F. J., Yao, Y., Pogribny, I., & Kovalchuk, I.
- Venue
- Nucleic Acids Research
- Publisher
- Oxford University Press (OUP)
- Published
- 2007-02-20
- Volume
- 35
- Issue
- 5
- Pages
- 1714-1725
- ISSN
- 0305-1048 (ISSN-L)
- 1362-4962
- OpenAlex
- W2077784322
- Cited by
- 317
- References
- 48
- FWCI
- 21.18
- Type
- journal article
- Language
- en
- Open access
- gold
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Transgenerational changes in the genome stability and methylation in pathogen-infected plants. https://app.cochat.ai/papers/10.1093/nar/gkm029
- The paper
- Boyko, A., Kathiria, P., Zemp, F. J., Yao, Y., Pogribny, I., & Kovalchuk, I. (2007). Transgenerational changes in the genome stability and methylation in pathogen-infected plants. Nucleic Acids Research. https://doi.org/10.1093/nar/gkm029
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
